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127 related items for PubMed ID: 16465244

  • 1. Modulation of the expression of Bcl-2 and related proteins in human leukemia cells by protein kinase C activators: relationship to effects on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis.
    Bartimole TM, Vrana JA, Freemerman AJ, Jarvis WD, Reed JC, Boise LH, Grant S.
    Cell Death Differ; 1997 May; 4(4):294-303. PubMed ID: 16465244
    [Abstract] [Full Text] [Related]

  • 2. Modulation of protein kinase C activity and calcium-sensitive isoform expression in human myeloid leukemia cells by bryostatin 1: relationship to differentiation and ara-C-induced apoptosis.
    Grant S, Turner AJ, Freemerman AJ, Wang Z, Kramer L, Jarvis WD.
    Exp Cell Res; 1996 Oct 10; 228(1):65-75. PubMed ID: 8892972
    [Abstract] [Full Text] [Related]

  • 3. Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA.
    Grant S, Jarvis WD, Swerdlow PS, Turner AJ, Traylor RS, Wallace HJ, Lin PS, Pettit GR, Gewirtz DA.
    Cancer Res; 1992 Nov 15; 52(22):6270-8. PubMed ID: 1423273
    [Abstract] [Full Text] [Related]

  • 4. Modulation of 1-[beta-D-arabinofuranosyl] cytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C.
    Grant S, Turner AJ, Bartimole TM, Nelms PA, Joe VC, Jarvis WD.
    Oncol Res; 1994 Nov 15; 6(2):87-99. PubMed ID: 7949469
    [Abstract] [Full Text] [Related]

  • 5. Enforced expression of Bcl-XS induces differentiation and sensitizes chronic myelogenous leukemia-blast crisis K562 cells to 1-beta-D-arabinofuranosylcytosine-mediated differentiation and apoptosis.
    Ray S, Bullock G, Nuñez G, Tang C, Ibrado AM, Huang Y, Bhalla K.
    Cell Growth Differ; 1996 Dec 15; 7(12):1617-23. PubMed ID: 8959329
    [Abstract] [Full Text] [Related]

  • 6. Effects of bryostatin 1 and other pharmacological activators of protein kinase C on 1-[beta-D-arabinofuranosyl]cytosine-induced apoptosis in HL-60 human promyelocytic leukemia cells.
    Jarvis WD, Povirk LF, Turner AJ, Traylor RS, Gewirtz DA, Pettit GR, Grant S.
    Biochem Pharmacol; 1994 Mar 02; 47(5):839-52. PubMed ID: 8135859
    [Abstract] [Full Text] [Related]

  • 7. Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2.
    Wang S, Vrana JA, Bartimole TM, Freemerman AJ, Jarvis WD, Kramer LB, Krystal G, Dent P, Grant S.
    Mol Pharmacol; 1997 Dec 02; 52(6):1000-9. PubMed ID: 9396780
    [Abstract] [Full Text] [Related]

  • 8. Potentiation of ara-C-induced apoptosis by the protein kinase C activator bryostatin 1 in human leukemia cells (HL-60) involves a process dependent upon c-Myc.
    Chelliah J, Freemerman AJ, Wu-Pong S, Jarvis WD, Grant S.
    Biochem Pharmacol; 1997 Sep 01; 54(5):563-73. PubMed ID: 9337072
    [Abstract] [Full Text] [Related]

  • 9. Effect of 1-beta-D-arabinofuranosylcytosine on apoptosis and differentiation in human monocytic leukemia cells (U937) expressing a c-Jun dominant-negative mutant protein (TAM67).
    Grant S, Freemerman AJ, Birrer MJ, Martin HA, Turner AJ, Szabo E, Chelliah J, Jarvis WD.
    Cell Growth Differ; 1996 May 01; 7(5):603-13. PubMed ID: 8732670
    [Abstract] [Full Text] [Related]

  • 10. Effects of bryostatin 1 and calcium ionophore (A23187) on apoptosis and differentiation in human myeloid leukemia cells (HL-60) following 1-beta-D-arabinofuranosylcytosine exposure.
    Vrana JA, Rao AS, Wang Z, Jarvis WD, Grant S.
    Int J Oncol; 1998 Apr 01; 12(4):927-34. PubMed ID: 9499457
    [Abstract] [Full Text] [Related]

  • 11. Evidence against a direct role for the induction of c-jun expression in the mediation of drug-induced apoptosis in human acute leukemia cells.
    Bullock G, Ray S, Reed J, Miyashita T, Maria Ibrado A, Huang Y, Bhalla K.
    Clin Cancer Res; 1995 May 01; 1(5):559-64. PubMed ID: 9816016
    [Abstract] [Full Text] [Related]

  • 12. Modulation of cIAP-1 by novel antitubulin agents when combined with bryostatin 1 results in increased apoptosis in the human early pre-B acute lymphoblastic leukemia cell line Reh.
    Wall NR, Mohammad RM, Nabha SM, Pettit GR, Al-Katib AM.
    Biochem Biophys Res Commun; 1999 Dec 09; 266(1):76-80. PubMed ID: 10581168
    [Abstract] [Full Text] [Related]

  • 13. Monocytic differentiation of HL-60 promyelocytic leukemia cells correlates with the induction of Bcl-xL.
    Chatterjee D, Han Z, Mendoza J, Goodglick L, Hendrickson EA, Pantazis P, Wyche JH.
    Cell Growth Differ; 1997 Oct 09; 8(10):1083-9. PubMed ID: 9342186
    [Abstract] [Full Text] [Related]

  • 14. Apoptosis-related gene expression affected by a GnRH analogue without induction of programmed cell death in LNCaP cells.
    Angelucci C, Iacopino F, Lama G, Capucci S, Zelano G, Boca M, Pistilli A, Sica G.
    Anticancer Res; 2004 Oct 09; 24(5A):2729-38. PubMed ID: 15517879
    [Abstract] [Full Text] [Related]

  • 15. Phase I trial and correlative laboratory studies of bryostatin 1 (NSC 339555) and high-dose 1-B-D-arabinofuranosylcytosine in patients with refractory acute leukemia.
    Cragg LH, Andreeff M, Feldman E, Roberts J, Murgo A, Winning M, Tombes MB, Roboz G, Kramer L, Grant S.
    Clin Cancer Res; 2002 Jul 09; 8(7):2123-33. PubMed ID: 12114412
    [Abstract] [Full Text] [Related]

  • 16. The three-substituted indolinone cyclin-dependent kinase 2 inhibitor 3-[1-(3H-imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one (SU9516) kills human leukemia cells via down-regulation of Mcl-1 through a transcriptional mechanism.
    Gao N, Kramer L, Rahmani M, Dent P, Grant S.
    Mol Pharmacol; 2006 Aug 09; 70(2):645-55. PubMed ID: 16672643
    [Abstract] [Full Text] [Related]

  • 17. Bryostatin induces changes in protein kinase C location and activity without altering c-myc gene expression in human promyelocytic leukemia cells (HL-60).
    Kraft AS, Baker VV, May WS.
    Oncogene; 1987 May 09; 1(2):111-8. PubMed ID: 3325877
    [Abstract] [Full Text] [Related]

  • 18. Potentiation of the activity of nitric oxide by the protein kinase C activator phorbol ester in human myeloid leukemic HL-60 cells: association with enhanced fragmentation of mature genomic DNA.
    Jun CD, Park SJ, Choi BM, Kwak HJ, Park YC, Kim MS, Park RK, Chung HT.
    Cell Immunol; 1997 Feb 25; 176(1):41-9. PubMed ID: 9070316
    [Abstract] [Full Text] [Related]

  • 19. Bryostatin 1 and UCN-01 potentiate 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human myeloid leukemia cells through disparate mechanisms.
    Wang S, Wang Z, Grant S.
    Mol Pharmacol; 2003 Jan 25; 63(1):232-42. PubMed ID: 12488556
    [Abstract] [Full Text] [Related]

  • 20. Effect of AS101 on bryostatin 1-mediated differentiation induction, cell cycle arrest, and modulation of drug-induced apoptosis in human myeloid leukemia cells.
    Rao AS, Freemerman AJ, Jarvis WD, Chelliah J, Bear HD, Mikkelsen R, Grant S.
    Leukemia; 1996 Jul 25; 10(7):1150-8. PubMed ID: 8683995
    [Abstract] [Full Text] [Related]

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