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Journal Abstract Search

91 related items for PubMed ID: 16466667

  • 1. Selective targeting of pentoxifylline to hepatic stellate cells using a novel platinum-based linker technology.
    Gonzalo T, Talman EG, van de Ven A, Temming K, Greupink R, Beljaars L, Reker-Smit C, Meijer DK, Molema G, Poelstra K, Kok RJ.
    J Control Release; 2006 Mar 10; 111(1-2):193-203. PubMed ID: 16466667
    [Abstract] [Full Text] [Related]

  • 2. Local inhibition of liver fibrosis by specific delivery of a platelet-derived growth factor kinase inhibitor to hepatic stellate cells.
    Gonzalo T, Beljaars L, van de Bovenkamp M, Temming K, van Loenen AM, Reker-Smit C, Meijer DK, Lacombe M, Opdam F, Kéri G, Orfi L, Poelstra K, Kok RJ.
    J Pharmacol Exp Ther; 2007 Jun 10; 321(3):856-65. PubMed ID: 17369283
    [Abstract] [Full Text] [Related]

  • 3. The antiproliferative drug doxorubicin inhibits liver fibrosis in bile duct-ligated rats and can be selectively delivered to hepatic stellate cells in vivo.
    Greupink R, Bakker HI, Bouma W, Reker-Smit C, Meijer DK, Beljaars L, Poelstra K.
    J Pharmacol Exp Ther; 2006 May 10; 317(2):514-21. PubMed ID: 16439617
    [Abstract] [Full Text] [Related]

  • 4. Targeting 15d-prostaglandin J2 to hepatic stellate cells: two options evaluated.
    Hagens WI, Mattos A, Greupink R, de Jager-Krikken A, Reker-Smit C, van Loenen-Weemaes A, Gouw IA, Poelstra K, Beljaars L.
    Pharm Res; 2007 Mar 10; 24(3):566-74. PubMed ID: 17245650
    [Abstract] [Full Text] [Related]

  • 5. Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats.
    Moreno M, Gonzalo T, Kok RJ, Sancho-Bru P, van Beuge M, Swart J, Prakash J, Temming K, Fondevila C, Beljaars L, Lacombe M, van der Hoeven P, Arroyo V, Poelstra K, Brenner DA, Ginès P, Bataller R.
    Hepatology; 2010 Mar 10; 51(3):942-52. PubMed ID: 20044807
    [Abstract] [Full Text] [Related]

  • 6. Albumin modified with mannose 6-phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells.
    Beljaars L, Molema G, Weert B, Bonnema H, Olinga P, Groothuis GM, Meijer DK, Poelstra K.
    Hepatology; 1999 May 10; 29(5):1486-93. PubMed ID: 10216133
    [Abstract] [Full Text] [Related]

  • 7. Increased liver uptake and reduced hepatic stellate cell activation with a cell-specific conjugate of the Rho-kinase inhibitor Y27632.
    van Beuge MM, Prakash J, Lacombe M, Post E, Reker-Smit C, Beljaars L, Poelstra K.
    Pharm Res; 2011 Aug 10; 28(8):2045-54. PubMed ID: 21442374
    [Abstract] [Full Text] [Related]

  • 8. Pharmacokinetics of a hepatic stellate cell-targeted doxorubicin construct in bile duct-ligated rats.
    Greupink R, Reker-Smit C, Proost JH, van Loenen Weemaes AM, de Hooge M, Poelstra K, Beljaars L.
    Biochem Pharmacol; 2007 May 01; 73(9):1455-62. PubMed ID: 17239825
    [Abstract] [Full Text] [Related]

  • 9. Reduction of fibrogenesis by selective delivery of a Rho kinase inhibitor to hepatic stellate cells in mice.
    van Beuge MM, Prakash J, Lacombe M, Gosens R, Post E, Reker-Smit C, Beljaars L, Poelstra K.
    J Pharmacol Exp Ther; 2011 Jun 01; 337(3):628-35. PubMed ID: 21383021
    [Abstract] [Full Text] [Related]

  • 10. Nicotinamide induces apoptosis and reduces collagen I and pro-inflammatory cytokines expression in rat hepatic stellate cells.
    Traister A, Breitman I, Bar-Lev E, Zvibel I, Harel A, Halpern Z, Oren R.
    Scand J Gastroenterol; 2005 Oct 01; 40(10):1226-34. PubMed ID: 16165703
    [Abstract] [Full Text] [Related]

  • 11. Peptide-modified albumin carrier explored as a novel strategy for a cell-specific delivery of interferon gamma to treat liver fibrosis.
    Bansal R, Prakash J, de Ruijter M, Beljaars L, Poelstra K.
    Mol Pharm; 2011 Oct 03; 8(5):1899-909. PubMed ID: 21800888
    [Abstract] [Full Text] [Related]

  • 12. Disease-induced drug targeting using novel peptide-ligand albumins.
    Meijer DK, Beljaars L, Molema G, Poelstra K.
    J Control Release; 2001 May 14; 72(1-3):157-64. PubMed ID: 11389994
    [Abstract] [Full Text] [Related]

  • 13. Effect of fetuin, a TGFbeta antagonist and pentoxifylline, a cytokine antagonist on hepatic stellate cell function and fibrotic parameters in fibrosis.
    Verma-Gandhu M, Peterson MR, Peterson TC.
    Eur J Pharmacol; 2007 Oct 31; 572(2-3):220-7. PubMed ID: 17678645
    [Abstract] [Full Text] [Related]

  • 14. Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis.
    Beljaars L, Meijer DK, Poelstra K.
    Front Biosci; 2002 May 01; 7():e214-22. PubMed ID: 11991830
    [Abstract] [Full Text] [Related]

  • 15. Pentoxifylline inhibits growth and collagen synthesis of cultured human hepatic myofibroblast-like cells.
    Préaux AM, Mallat A, Rosenbaum J, Zafrani ES, Mavier P.
    Hepatology; 1997 Aug 01; 26(2):315-22. PubMed ID: 9252140
    [Abstract] [Full Text] [Related]

  • 16. Effects of a new bioactive lipid-based drug carrier on cultured hepatic stellate cells and liver fibrosis in bile duct-ligated rats.
    Adrian JE, Poelstra K, Scherphof GL, Meijer DK, van Loenen-Weemaes AM, Reker-Smit C, Morselt HW, Zwiers P, Kamps JA.
    J Pharmacol Exp Ther; 2007 May 01; 321(2):536-43. PubMed ID: 17314198
    [Abstract] [Full Text] [Related]

  • 17. Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell.
    Greupink R, Bakker HI, Reker-Smit C, van Loenen-Weemaes AM, Kok RJ, Meijer DK, Beljaars L, Poelstra K.
    J Hepatol; 2005 Nov 01; 43(5):884-92. PubMed ID: 16083988
    [Abstract] [Full Text] [Related]

  • 18. K⁺-channel inhibition reduces portal perfusion pressure in fibrotic rats and fibrosis associated characteristics of hepatic stellate cells.
    Freise C, Heldwein S, Erben U, Hoyer J, Köhler R, Jöhrens K, Patsenker E, Ruehl M, Seehofer D, Stickel F, Somasundaram R.
    Liver Int; 2015 Apr 01; 35(4):1244-52. PubMed ID: 25212242
    [Abstract] [Full Text] [Related]

  • 19. Cellular targeting of the apoptosis-inducing compound gliotoxin to fibrotic rat livers.
    Hagens WI, Beljaars L, Mann DA, Wright MC, Julien B, Lotersztajn S, Reker-Smit C, Poelstra K.
    J Pharmacol Exp Ther; 2008 Mar 01; 324(3):902-10. PubMed ID: 18077624
    [Abstract] [Full Text] [Related]

  • 20. A novel lipid-based drug carrier targeted to the non-parenchymal cells, including hepatic stellate cells, in the fibrotic livers of bile duct ligated rats.
    Adrian JE, Kamps JA, Scherphof GL, Meijer DK, van Loenen-Weemaes AM, Reker-Smit C, Terpstra P, Poelstra K.
    Biochim Biophys Acta; 2007 Jun 01; 1768(6):1430-9. PubMed ID: 17493581
    [Abstract] [Full Text] [Related]

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