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187 related items for PubMed ID: 16472687

  • 1. Rational design and applications of a Rac GTPase-specific small molecule inhibitor.
    Akbar H, Cancelas J, Williams DA, Zheng J, Zheng Y.
    Methods Enzymol; 2006; 406():554-65. PubMed ID: 16472687
    [Abstract] [Full Text] [Related]

  • 2. Rational design and characterization of a Rac GTPase-specific small molecule inhibitor.
    Gao Y, Dickerson JB, Guo F, Zheng J, Zheng Y.
    Proc Natl Acad Sci U S A; 2004 May 18; 101(20):7618-23. PubMed ID: 15128949
    [Abstract] [Full Text] [Related]

  • 3. Structure-function based design of small molecule inhibitors targeting Rho family GTPases.
    Nassar N, Cancelas J, Zheng J, Williams DA, Zheng Y.
    Curr Top Med Chem; 2006 May 18; 6(11):1109-16. PubMed ID: 16842149
    [Abstract] [Full Text] [Related]

  • 4. Rho GTPases and regulation of hematopoietic stem cell localization.
    Williams DA, Zheng Y, Cancelas JA.
    Methods Enzymol; 2008 May 18; 439():365-93. PubMed ID: 18374178
    [Abstract] [Full Text] [Related]

  • 5. Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization.
    Cancelas JA, Lee AW, Prabhakar R, Stringer KF, Zheng Y, Williams DA.
    Nat Med; 2005 Aug 18; 11(8):886-91. PubMed ID: 16025125
    [Abstract] [Full Text] [Related]

  • 6. Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.
    Debreceni B, Gao Y, Guo F, Zhu K, Jia B, Zheng Y.
    J Biol Chem; 2004 Jan 30; 279(5):3777-86. PubMed ID: 14597635
    [Abstract] [Full Text] [Related]

  • 7. HGF attenuates thrombin-induced endothelial permeability by Tiam1-mediated activation of the Rac pathway and by Tiam1/Rac-dependent inhibition of the Rho pathway.
    Birukova AA, Alekseeva E, Mikaelyan A, Birukov KG.
    FASEB J; 2007 Sep 30; 21(11):2776-86. PubMed ID: 17428964
    [Abstract] [Full Text] [Related]

  • 8. [Role of the multifunctional Trio protein in the control of the Rac1 and RhoA gtpase signaling pathways].
    Bellanger JM, Zugasti O, Lazaro JB, Diriong S, Lamb N, Sardet C, Debant A.
    C R Seances Soc Biol Fil; 1998 Sep 30; 192(2):367-74. PubMed ID: 9759378
    [Abstract] [Full Text] [Related]

  • 9. Growth factor induced activation of Rho and Rac GTPases and actin cytoskeletal reorganization in human lens epithelial cells.
    Maddala R, Reddy VN, Epstein DL, Rao V.
    Mol Vis; 2003 Jul 17; 9():329-36. PubMed ID: 12876554
    [Abstract] [Full Text] [Related]

  • 10. G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.
    Niu J, Profirovic J, Pan H, Vaiskunaite R, Voyno-Yasenetskaya T.
    Circ Res; 2003 Oct 31; 93(9):848-56. PubMed ID: 14512443
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of Rac activity alleviates lipopolysaccharide-induced acute pulmonary injury in mice.
    Yao HY, Chen L, Xu C, Wang J, Chen J, Xie QM, Wu X, Yan XF.
    Biochim Biophys Acta; 2011 Jul 31; 1810(7):666-74. PubMed ID: 21511011
    [Abstract] [Full Text] [Related]

  • 12. P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophils.
    Dong X, Mo Z, Bokoch G, Guo C, Li Z, Wu D.
    Curr Biol; 2005 Oct 25; 15(20):1874-9. PubMed ID: 16243036
    [Abstract] [Full Text] [Related]

  • 13. Caspase-mediated cleavage of the TIAM1 guanine nucleotide exchange factor during apoptosis.
    Qi H, Juo P, Masuda-Robens J, Caloca MJ, Zhou H, Stone N, Kazanietz MG, Chou MM.
    Cell Growth Differ; 2001 Dec 25; 12(12):603-11. PubMed ID: 11751455
    [Abstract] [Full Text] [Related]

  • 14. A role for Rac in Tiam1-induced membrane ruffling and invasion.
    Michiels F, Habets GG, Stam JC, van der Kammen RA, Collard JG.
    Nature; 1995 May 25; 375(6529):338-40. PubMed ID: 7753201
    [Abstract] [Full Text] [Related]

  • 15. Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling.
    Stam JC, Michiels F, van der Kammen RA, Moolenaar WH, Collard JG.
    EMBO J; 1998 Jul 15; 17(14):4066-74. PubMed ID: 9670021
    [Abstract] [Full Text] [Related]

  • 16. Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism.
    Lambert JM, Lambert QT, Reuther GW, Malliri A, Siderovski DP, Sondek J, Collard JG, Der CJ.
    Nat Cell Biol; 2002 Aug 15; 4(8):621-5. PubMed ID: 12134164
    [Abstract] [Full Text] [Related]

  • 17. Dock6, a Dock-C subfamily guanine nucleotide exchanger, has the dual specificity for Rac1 and Cdc42 and regulates neurite outgrowth.
    Miyamoto Y, Yamauchi J, Sanbe A, Tanoue A.
    Exp Cell Res; 2007 Feb 15; 313(4):791-804. PubMed ID: 17196961
    [Abstract] [Full Text] [Related]

  • 18. Molecular basis for Rac1 recognition by guanine nucleotide exchange factors.
    Karnoub AE, Worthylake DK, Rossman KL, Pruitt WM, Campbell SL, Sondek J, Der CJ.
    Nat Struct Biol; 2001 Dec 15; 8(12):1037-41. PubMed ID: 11685227
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of Rac1 decreases the severity of pancreatitis and pancreatitis-associated lung injury in mice.
    Binker MG, Binker-Cosen AA, Gaisano HY, Cosen-Binker LI.
    Exp Physiol; 2008 Oct 15; 93(10):1091-103. PubMed ID: 18567599
    [Abstract] [Full Text] [Related]

  • 20. Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.
    Shutes A, Onesto C, Picard V, Leblond B, Schweighoffer F, Der CJ.
    J Biol Chem; 2007 Dec 07; 282(49):35666-78. PubMed ID: 17932039
    [Abstract] [Full Text] [Related]

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