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179 related items for PubMed ID: 16473451

  • 1. Roles of endogenous ascorbate and glutathione in the cellular reduction and cytotoxicity of sulfamethoxazole-nitroso.
    Lavergne SN, Kurian JR, Bajad SU, Maki JE, Yoder AR, Guzinski MV, Graziano FM, Trepanier LA.
    Toxicology; 2006 May 01; 222(1-2):25-36. PubMed ID: 16473451
    [Abstract] [Full Text] [Related]

  • 2. Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Implications for idiosyncratic toxicity.
    Cribb AE, Miller M, Leeder JS, Hill J, Spielberg SP.
    Drug Metab Dispos; 1991 May 01; 19(5):900-6. PubMed ID: 1686233
    [Abstract] [Full Text] [Related]

  • 3. Evaluation of the clinical, immunologic, and biochemical effects of nitroso sulfamethoxazole administration to dogs: a pilot study.
    Lavergne SN, Volkman EM, Maki JE, Yoder AR, Trepanier LA.
    Toxicology; 2005 Mar 01; 208(1):63-72. PubMed ID: 15664433
    [Abstract] [Full Text] [Related]

  • 4. Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine.
    Bhusari S, Abouraya M, Padilla ML, Pinkerton ME, Drescher NJ, Sacco JC, Trepanier LA.
    Arch Toxicol; 2010 Aug 01; 84(8):597-607. PubMed ID: 20221587
    [Abstract] [Full Text] [Related]

  • 5. In vitro formation, disposition and toxicity of N-acetoxy-sulfamethoxazole, a potential mediator of sulfamethoxazole toxicity.
    Nakamura H, Uetrecht J, Cribb AE, Miller MA, Zahid N, Hill J, Josephy PD, Grant DM, Spielberg SP.
    J Pharmacol Exp Ther; 1995 Sep 01; 274(3):1099-104. PubMed ID: 7562475
    [Abstract] [Full Text] [Related]

  • 6. Plasma ascorbate deficiency is associated with impaired reduction of sulfamethoxazole-nitroso in HIV infection.
    Trepanier LA, Yoder AR, Bajad S, Beckwith MD, Bellehumeur JL, Graziano FM.
    J Acquir Immune Defic Syndr; 2004 Aug 15; 36(5):1041-50. PubMed ID: 15247557
    [Abstract] [Full Text] [Related]

  • 7. Is hydroxylamine-induced cytotoxicity a valid marker for hypersensitivity reactions to sulfamethoxazole in human immunodeficiency virus-infected individuals?
    Reilly TP, MacArthur RD, Farrough MJ, Crane LR, Woster PM, Svensson CK.
    J Pharmacol Exp Ther; 1999 Dec 15; 291(3):1356-64. PubMed ID: 10565861
    [Abstract] [Full Text] [Related]

  • 8. In vitro cytotoxicity as a marker of hypersensitivity to sulphamethoxazole in patients with HIV.
    Carr A, Tindall B, Penny R, Cooper DA.
    Clin Exp Immunol; 1993 Oct 15; 94(1):21-5. PubMed ID: 8403509
    [Abstract] [Full Text] [Related]

  • 9. Covalent binding of sulfamethoxazole reactive metabolites to human and rat liver subcellular fractions assessed by immunochemical detection.
    Cribb AE, Nuss CE, Alberts DW, Lamphere DB, Grant DM, Grossman SJ, Spielberg SP.
    Chem Res Toxicol; 1996 Mar 15; 9(2):500-7. PubMed ID: 8839055
    [Abstract] [Full Text] [Related]

  • 10. Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans.
    Farrell J, Naisbitt DJ, Drummond NS, Depta JP, Vilar FJ, Pirmohamed M, Park BK.
    J Pharmacol Exp Ther; 2003 Jul 15; 306(1):229-37. PubMed ID: 12676884
    [Abstract] [Full Text] [Related]

  • 11. Role of Oxidative Stress in Hypersensitivity Reactions to Sulfonamides.
    Elzagallaai AA, Sultan EA, Bend JR, Abuzgaia AM, Loubani E, Rieder MJ.
    J Clin Pharmacol; 2020 Mar 15; 60(3):409-421. PubMed ID: 31709574
    [Abstract] [Full Text] [Related]

  • 12. Reactive oxygen species generation and its role in the differential cytotoxicity of the arylhydroxylamine metabolites of sulfamethoxazole and dapsone in normal human epidermal keratinocytes.
    Vyas PM, Roychowdhury S, Woster PM, Svensson CK.
    Biochem Pharmacol; 2005 Jul 15; 70(2):275-86. PubMed ID: 15894292
    [Abstract] [Full Text] [Related]

  • 13. Ascorbic acid decreases oxidant stress in endothelial cells caused by the nitroxide tempol.
    May JM, Qu ZC, Juliao S, Cobb CE.
    Free Radic Res; 2005 Feb 15; 39(2):195-202. PubMed ID: 15763967
    [Abstract] [Full Text] [Related]

  • 14. The association of opportunistic infections with the occurrence of trimethoprim/sulfamethoxazole hypersensitivity in patients infected with human immunodeficiency virus.
    Lehmann DF, Liu A, Newman N, Blair DC.
    J Clin Pharmacol; 1999 May 15; 39(5):533-7. PubMed ID: 10234602
    [Abstract] [Full Text] [Related]

  • 15. Hypersensitivity of HIV-1-infected cells to reactive sulfonamide metabolites correlated to expression of the HIV-1 viral protein tat.
    Arp J, Rieder MJ, Urquhart B, Freeman D, Tucker MJ, Krizova A, Lehmann D, Dekaban GA.
    J Pharmacol Exp Ther; 2005 Sep 15; 314(3):1218-25. PubMed ID: 15933158
    [Abstract] [Full Text] [Related]

  • 16. The hydroxylamine of sulfamethoxazole synergizes with FK506 and cyclosporin A, inhibiting T-cell proliferation.
    Hess DA, Bird IA, Almawi WY, Rieder MJ.
    J Pharmacol Exp Ther; 1997 Apr 15; 281(1):540-8. PubMed ID: 9103542
    [Abstract] [Full Text] [Related]

  • 17. Characterization of the formation and localization of sulfamethoxazole and dapsone-associated drug-protein adducts in human epidermal keratinocytes.
    Roychowdhury S, Vyas PM, Reilly TP, Gaspari AA, Svensson CK.
    J Pharmacol Exp Ther; 2005 Jul 15; 314(1):43-52. PubMed ID: 15784651
    [Abstract] [Full Text] [Related]

  • 18. Methemoglobin formation by hydroxylamine metabolites of sulfamethoxazole and dapsone: implications for differences in adverse drug reactions.
    Reilly TP, Woster PM, Svensson CK.
    J Pharmacol Exp Ther; 1999 Mar 15; 288(3):951-9. PubMed ID: 10027831
    [Abstract] [Full Text] [Related]

  • 19. Reduction of sulfamethoxazole and dapsone hydroxylamines by a microsomal enzyme system purified from pig liver and pig and human liver microsomes.
    Clement B, Behrens D, Amschler J, Matschke K, Wolf S, Havemeyer A.
    Life Sci; 2005 May 27; 77(2):205-19. PubMed ID: 15862605
    [Abstract] [Full Text] [Related]

  • 20. Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells. An in vitro comparative study.
    Verrax J, Delvaux M, Beghein N, Taper H, Gallez B, Buc Calderon P.
    Free Radic Res; 2005 Jun 27; 39(6):649-57. PubMed ID: 16036343
    [Abstract] [Full Text] [Related]

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