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797 related items for PubMed ID: 16478725

  • 1. Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis.
    Han J, Goldstein LA, Gastman BR, Rabinowich H.
    J Biol Chem; 2006 Apr 14; 281(15):10153-63. PubMed ID: 16478725
    [Abstract] [Full Text] [Related]

  • 2. Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells.
    Weng C, Li Y, Xu D, Shi Y, Tang H.
    J Biol Chem; 2005 Mar 18; 280(11):10491-500. PubMed ID: 15637055
    [Abstract] [Full Text] [Related]

  • 3. Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events.
    Han J, Goldstein LA, Gastman BR, Froelich CJ, Yin XM, Rabinowich H.
    J Biol Chem; 2004 May 21; 279(21):22020-9. PubMed ID: 15014070
    [Abstract] [Full Text] [Related]

  • 4. Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation.
    Rosato RR, Dai Y, Almenara JA, Maggio SC, Grant S.
    Leukemia; 2004 Nov 21; 18(11):1780-8. PubMed ID: 15385934
    [Abstract] [Full Text] [Related]

  • 5. Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.
    Wang YF, Jiang CC, Kiejda KA, Gillespie S, Zhang XD, Hersey P.
    Clin Cancer Res; 2007 Aug 15; 13(16):4934-42. PubMed ID: 17652623
    [Abstract] [Full Text] [Related]

  • 6. Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis.
    Han J, Goldstein LA, Gastman BR, Rabinovitz A, Rabinowich H.
    J Biol Chem; 2005 Apr 22; 280(16):16383-92. PubMed ID: 15713684
    [Abstract] [Full Text] [Related]

  • 7. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S, Borrow J, Zhang XD, Hersey P.
    Apoptosis; 2006 Dec 22; 11(12):2251-65. PubMed ID: 17051334
    [Abstract] [Full Text] [Related]

  • 8. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A, Sun J, Doi K, Sung SS, Takahashi Y, Yin H, Rodriguez JM, Becerril J, Berndt N, Hamilton AD, Wang HG, Sebti SM.
    J Biol Chem; 2011 Mar 18; 286(11):9382-92. PubMed ID: 21148306
    [Abstract] [Full Text] [Related]

  • 9. The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim.
    Nikrad M, Johnson T, Puthalalath H, Coultas L, Adams J, Kraft AS.
    Mol Cancer Ther; 2005 Mar 18; 4(3):443-9. PubMed ID: 15767553
    [Abstract] [Full Text] [Related]

  • 10. Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis.
    Clohessy JG, Zhuang J, de Boer J, Gil-Gómez G, Brady HJ.
    J Biol Chem; 2006 Mar 03; 281(9):5750-9. PubMed ID: 16380381
    [Abstract] [Full Text] [Related]

  • 11. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO).
    Ng CP, Bonavida B.
    Mol Cancer Ther; 2002 Oct 03; 1(12):1051-8. PubMed ID: 12481428
    [Abstract] [Full Text] [Related]

  • 12. Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival.
    Rubert J, Qian Z, Andraos R, Guthy DA, Radimerski T.
    BMC Cancer; 2011 Jan 19; 11():24. PubMed ID: 21247487
    [Abstract] [Full Text] [Related]

  • 13. BH3 mimetic obatoclax enhances TRAIL-mediated apoptosis in human pancreatic cancer cells.
    Huang S, Okumura K, Sinicrope FA.
    Clin Cancer Res; 2009 Jan 01; 15(1):150-9. PubMed ID: 19118042
    [Abstract] [Full Text] [Related]

  • 14. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 15. Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.
    Meng XW, Lee SH, Dai H, Loegering D, Yu C, Flatten K, Schneider P, Dai NT, Kumar SK, Smith BD, Karp JE, Adjei AA, Kaufmann SH.
    J Biol Chem; 2007 Oct 12; 282(41):29831-46. PubMed ID: 17698840
    [Abstract] [Full Text] [Related]

  • 16. Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria.
    Zhang XD, Borrow JM, Zhang XY, Nguyen T, Hersey P.
    Oncogene; 2003 May 15; 22(19):2869-81. PubMed ID: 12771938
    [Abstract] [Full Text] [Related]

  • 17. Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway.
    Wagner KW, Engels IH, Deveraux QL.
    J Biol Chem; 2004 Aug 13; 279(33):35047-52. PubMed ID: 15173176
    [Abstract] [Full Text] [Related]

  • 18. Mcl-1 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in human cholangiocarcinoma cells.
    Taniai M, Grambihler A, Higuchi H, Werneburg N, Bronk SF, Farrugia DJ, Kaufmann SH, Gores GJ.
    Cancer Res; 2004 May 15; 64(10):3517-24. PubMed ID: 15150106
    [Abstract] [Full Text] [Related]

  • 19. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
    Huang S, Sinicrope FA.
    Cancer Res; 2008 Apr 15; 68(8):2944-51. PubMed ID: 18413764
    [Abstract] [Full Text] [Related]

  • 20. BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins.
    Weber A, Paschen SA, Heger K, Wilfling F, Frankenberg T, Bauerschmitt H, Seiffert BM, Kirschnek S, Wagner H, Häcker G.
    J Cell Biol; 2007 May 21; 177(4):625-36. PubMed ID: 17517961
    [Abstract] [Full Text] [Related]


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