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86 related items for PubMed ID: 16488473

  • 1. Effect of lysophosphatidic acid acyltransferase-beta inhibition in acute leukemia.
    Douvas MG, Hogan KN, Ji Y, Hollenback D, Bonham L, Singer JW, Mitchell BS.
    Leuk Res; 2006 Aug; 30(8):1027-36. PubMed ID: 16488473
    [Abstract] [Full Text] [Related]

  • 2. Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.
    Pagel JM, Laugen C, Bonham L, Hackman RC, Hockenbery DM, Bhatt R, Hollenback D, Carew H, Singer JW, Press OW.
    Clin Cancer Res; 2005 Jul 01; 11(13):4857-66. PubMed ID: 16000584
    [Abstract] [Full Text] [Related]

  • 3. Antileukemic activity of lysophosphatidic acid acyltransferase-beta inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib.
    La Rosée P, Jia T, Demehri S, Härtel N, de Vries P, Bonham L, Hollenback D, Singer JW, Melo JV, Druker BJ, Deininger MW.
    Clin Cancer Res; 2006 Nov 01; 12(21):6540-6. PubMed ID: 17085669
    [Abstract] [Full Text] [Related]

  • 4. Lysophosphatidic acid acyltransferase-beta is a prognostic marker and therapeutic target in gynecologic malignancies.
    Springett GM, Bonham L, Hummer A, Linkov I, Misra D, Ma C, Pezzoni G, Di Giovine S, Singer J, Kawasaki H, Spriggs D, Soslow R, Dupont J.
    Cancer Res; 2005 Oct 15; 65(20):9415-25. PubMed ID: 16230405
    [Abstract] [Full Text] [Related]

  • 5. Lysophosphatidic acid acyltransferase-beta: a novel target for induction of tumour cell apoptosis.
    Bonham L, Leung DW, White T, Hollenback D, Klein P, Tulinsky J, Coon M, de Vries P, Singer JW.
    Expert Opin Ther Targets; 2003 Oct 15; 7(5):643-61. PubMed ID: 14498826
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, SAR, and antitumor properties of diamino-C,N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase-beta.
    Gong B, Hong F, Kohm C, Jenkins S, Tulinsky J, Bhatt R, De Vries P, Singer JW, Klein P.
    Bioorg Med Chem Lett; 2004 May 03; 14(9):2303-8. PubMed ID: 15081029
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and SAR of 2-arylbenzoxazoles, benzothiazoles and benzimidazoles as inhibitors of lysophosphatidic acid acyltransferase-beta.
    Gong B, Hong F, Kohm C, Bonham L, Klein P.
    Bioorg Med Chem Lett; 2004 Mar 22; 14(6):1455-9. PubMed ID: 15006381
    [Abstract] [Full Text] [Related]

  • 8. Diamino-C,N-diarylpyridine positional isomers as inhibitors of lysophosphatidic acid acyltransferase-beta.
    Hong F, Hollenback D, Singer JW, Klein P.
    Bioorg Med Chem Lett; 2005 Nov 01; 15(21):4703-7. PubMed ID: 16143520
    [Abstract] [Full Text] [Related]

  • 9. Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A.
    Lu MC, Du YC, Chuu JJ, Hwang SL, Hsieh PC, Hung CS, Chang FR, Wu YC.
    Arch Toxicol; 2009 Feb 01; 83(2):121-9. PubMed ID: 18709356
    [Abstract] [Full Text] [Related]

  • 10. Programmed cell death-4 tumor suppressor protein contributes to retinoic acid-induced terminal granulocytic differentiation of human myeloid leukemia cells.
    Ozpolat B, Akar U, Steiner M, Zorrilla-Calancha I, Tirado-Gomez M, Colburn N, Danilenko M, Kornblau S, Berestein GL.
    Mol Cancer Res; 2007 Jan 01; 5(1):95-108. PubMed ID: 17259349
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of lysophosphatidic acid acyltransferase beta disrupts proliferative and survival signals in normal cells and induces apoptosis of tumor cells.
    Coon M, Ball A, Pound J, Ap S, Hollenback D, White T, Tulinsky J, Bonham L, Morrison DK, Finney R, Singer JW.
    Mol Cancer Ther; 2003 Oct 01; 2(10):1067-78. PubMed ID: 14578472
    [Abstract] [Full Text] [Related]

  • 12. Piplartine induces inhibition of leukemia cell proliferation triggering both apoptosis and necrosis pathways.
    Bezerra DP, Militão GC, de Castro FO, Pessoa C, de Moraes MO, Silveira ER, Lima MA, Elmiro FJ, Costa-Lotufo LV.
    Toxicol In Vitro; 2007 Feb 01; 21(1):1-8. PubMed ID: 16971088
    [Abstract] [Full Text] [Related]

  • 13. Antitumor effects of celecoxib on K562 leukemia cells are mediated by cell-cycle arrest, caspase-3 activation, and downregulation of Cox-2 expression and are synergistic with hydroxyurea or imatinib.
    Zhang GS, Liu DS, Dai CW, Li RJ.
    Am J Hematol; 2006 Apr 01; 81(4):242-55. PubMed ID: 16550520
    [Abstract] [Full Text] [Related]

  • 14. Modulation of ceramide metabolism in T-leukemia cell lines potentiates apoptosis induced by the cationic antimicrobial peptide bovine lactoferricin.
    Furlong SJ, Ridgway ND, Hoskin DW.
    Int J Oncol; 2008 Mar 01; 32(3):537-44. PubMed ID: 18292930
    [Abstract] [Full Text] [Related]

  • 15. Induction of apoptosis and inhibition of telomerase activity by trichostatin A, a histone deacetylase inhibitor, in human leukemic U937 cells.
    Woo HJ, Lee SJ, Choi BT, Park YM, Choi YH.
    Exp Mol Pathol; 2007 Feb 01; 82(1):77-84. PubMed ID: 16574101
    [Abstract] [Full Text] [Related]

  • 16. Pioglitazone inhibits the growth of human leukemia cell lines and primary leukemia cells while sparing normal hematopoietic stem cells.
    Saiki M, Hatta Y, Yamazaki T, Itoh T, Enomoto Y, Takeuchi J, Sawada U, Aizawa S, Horie T.
    Int J Oncol; 2006 Aug 01; 29(2):437-43. PubMed ID: 16820887
    [Abstract] [Full Text] [Related]

  • 17. 15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
    Shin SW, Seo CY, Han H, Han JY, Jeong JS, Kwak JY, Park JI.
    Clin Cancer Res; 2009 Sep 01; 15(17):5414-25. PubMed ID: 19690198
    [Abstract] [Full Text] [Related]

  • 18. Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade.
    Mandal C, Dutta A, Mallick A, Chandra S, Misra L, Sangwan RS, Mandal C.
    Apoptosis; 2008 Dec 01; 13(12):1450-64. PubMed ID: 18987975
    [Abstract] [Full Text] [Related]

  • 19. Antiproliferative effect of rapamycin on human T-cell leukemia cell line Jurkat by cell cycle arrest and telomerase inhibition.
    Zhao YM, Zhou Q, Xu Y, Lai XY, Huang H.
    Acta Pharmacol Sin; 2008 Apr 01; 29(4):481-8. PubMed ID: 18358095
    [Abstract] [Full Text] [Related]

  • 20. Tumor-specificity and type of cell death induced by trihaloacetylazulenes in human tumor cell lines.
    Sekine T, Takahashi J, Nishishiro M, Arai A, Wakabayashi H, Kurihara T, Kobayashi M, Hashimoto K, Kikuchi H, Katayama T, Kanda Y, Kunii S, Motohashi N, Sakagami H.
    Anticancer Res; 2007 Apr 01; 27(1A):133-43. PubMed ID: 17352225
    [Abstract] [Full Text] [Related]

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