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Journal Abstract Search

856 related items for PubMed ID: 16489022

  • 1. The tumor suppressor Smad4 is required for transforming growth factor beta-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells.
    Deckers M, van Dinther M, Buijs J, Que I, Löwik C, van der Pluijm G, ten Dijke P.
    Cancer Res; 2006 Feb 15; 66(4):2202-9. PubMed ID: 16489022
    [Abstract] [Full Text] [Related]

  • 2. Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer.
    Buijs JT, Henriquez NV, van Overveld PG, van der Horst G, Que I, Schwaninger R, Rentsch C, Ten Dijke P, Cleton-Jansen AM, Driouch K, Lidereau R, Bachelier R, Vukicevic S, Clézardin P, Papapoulos SE, Cecchini MG, Löwik CW, van der Pluijm G.
    Cancer Res; 2007 Sep 15; 67(18):8742-51. PubMed ID: 17875715
    [Abstract] [Full Text] [Related]

  • 3. Transcriptome profiling of a TGF-beta-induced epithelial-to-mesenchymal transition reveals extracellular clusterin as a target for therapeutic antibodies.
    Lenferink AE, Cantin C, Nantel A, Wang E, Durocher Y, Banville M, Paul-Roc B, Marcil A, Wilson MR, O'Connor-McCourt MD.
    Oncogene; 2010 Feb 11; 29(6):831-44. PubMed ID: 19935703
    [Abstract] [Full Text] [Related]

  • 4. Effects of RNAi-mediated Smad4 silencing on growth and apoptosis of human rhabdomyosarcoma cells.
    Ye L, Zhang H, Zhang L, Yang G, Ke Q, Guo H, Bu H.
    Int J Oncol; 2006 Nov 11; 29(5):1149-57. PubMed ID: 17016646
    [Abstract] [Full Text] [Related]

  • 5. Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses.
    Levy L, Hill CS.
    Mol Cell Biol; 2005 Sep 11; 25(18):8108-25. PubMed ID: 16135802
    [Abstract] [Full Text] [Related]

  • 6. Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo.
    Moore LD, Isayeva T, Siegal GP, Ponnazhagan S.
    Clin Cancer Res; 2008 Aug 01; 14(15):4961-70. PubMed ID: 18676771
    [Abstract] [Full Text] [Related]

  • 7. Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta.
    Jazag A, Ijichi H, Kanai F, Imamura T, Guleng B, Ohta M, Imamura J, Tanaka Y, Tateishi K, Ikenoue T, Kawakami T, Arakawa Y, Miyagishi M, Taira K, Kawabe T, Omata M.
    Oncogene; 2005 Jan 20; 24(4):662-71. PubMed ID: 15592526
    [Abstract] [Full Text] [Related]

  • 8. Smad4-independent TGF-beta signaling in tumor cell migration.
    Giehl K, Imamichi Y, Menke A.
    Cells Tissues Organs; 2007 Jan 20; 185(1-3):123-30. PubMed ID: 17587818
    [Abstract] [Full Text] [Related]

  • 9. Epithin, a target of transforming growth factor-beta signaling, mediates epithelial-mesenchymal transition.
    Lee HS, Kim C, Kim SB, Kim MG, Park D.
    Biochem Biophys Res Commun; 2010 May 14; 395(4):553-9. PubMed ID: 20398629
    [Abstract] [Full Text] [Related]

  • 10. Lentiviral-mediated Smad4 RNAi induced anti-proliferation by p16 up-regulation and apoptosis by caspase 3 down-regulation in hepatoma SMMC-7721 cells.
    Huang S, Zhang F, Miao L, Zhang H, Fan Z, Wang X, Ji G.
    Oncol Rep; 2008 Nov 14; 20(5):1053-9. PubMed ID: 18949401
    [Abstract] [Full Text] [Related]

  • 11. SMAD4 mediates mesenchymal-epithelial reversion in SW480 colon carcinoma cells.
    Pohl M, Radacz Y, Pawlik N, Schoeneck A, Baldus SE, Munding J, Schmiegel W, Schwarte-Waldhoff I, Reinacher-Schick A.
    Anticancer Res; 2010 Jul 14; 30(7):2603-13. PubMed ID: 20682989
    [Abstract] [Full Text] [Related]

  • 12. TGF beta-induced focal complex formation in epithelial cells is mediated by activated ERK and JNK MAP kinases and is independent of Smad4.
    Imamichi Y, Waidmann O, Hein R, Eleftheriou P, Giehl K, Menke A.
    Biol Chem; 2005 Mar 14; 386(3):225-36. PubMed ID: 15843168
    [Abstract] [Full Text] [Related]

  • 13. Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer.
    Hiraga T, Myoui A, Choi ME, Yoshikawa H, Yoneda T.
    Cancer Res; 2006 Feb 15; 66(4):2067-73. PubMed ID: 16489006
    [Abstract] [Full Text] [Related]

  • 14. Sp1 is required for transforming growth factor-beta-induced mesenchymal transition and migration in pancreatic cancer cells.
    Jungert K, Buck A, von Wichert G, Adler G, König A, Buchholz M, Gress TM, Ellenrieder V.
    Cancer Res; 2007 Feb 15; 67(4):1563-70. PubMed ID: 17308095
    [Abstract] [Full Text] [Related]

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  • 16. NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.
    Huber MA, Azoitei N, Baumann B, Grünert S, Sommer A, Pehamberger H, Kraut N, Beug H, Wirth T.
    J Clin Invest; 2004 Aug 15; 114(4):569-81. PubMed ID: 15314694
    [Abstract] [Full Text] [Related]

  • 17. Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway.
    Katsuno Y, Hanyu A, Kanda H, Ishikawa Y, Akiyama F, Iwase T, Ogata E, Ehata S, Miyazono K, Imamura T.
    Oncogene; 2008 Oct 23; 27(49):6322-33. PubMed ID: 18663362
    [Abstract] [Full Text] [Related]

  • 18. Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis.
    Gal A, Sjöblom T, Fedorova L, Imreh S, Beug H, Moustakas A.
    Oncogene; 2008 Feb 21; 27(9):1218-30. PubMed ID: 17724470
    [Abstract] [Full Text] [Related]

  • 19. Activation of extracellular signal-regulated kinase by TGF-beta1 via TbetaRII and Smad7 dependent mechanisms in human bronchial epithelial BEP2D cells.
    Huo YY, Hu YC, He XR, Wang Y, Song BQ, Zhou PK, Zhu MX, Li G, Wu DC.
    Cell Biol Toxicol; 2007 Mar 21; 23(2):113-28. PubMed ID: 17096210
    [Abstract] [Full Text] [Related]

  • 20. Transforming growth factor-beta1 and activin A generate antiproliferative signaling in thyroid cancer cells.
    Matsuo SE, Leoni SG, Colquhoun A, Kimura ET.
    J Endocrinol; 2006 Jul 21; 190(1):141-50. PubMed ID: 16837618
    [Abstract] [Full Text] [Related]

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