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Journal Abstract Search

130 related items for PubMed ID: 16492150

  • 1. Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product.
    Wipf P, Graham TH, Vogt A, Sikorski RP, Ducruet AP, Lazo JS.
    Chem Biol Drug Des; 2006 Jan; 67(1):66-73. PubMed ID: 16492150
    [Abstract] [Full Text] [Related]

  • 2. Methanolysis products of disorazole A1.
    Hearn BR, Arslanian RL, Fu H, Liu F, Gramajo H, Myles DC.
    J Nat Prod; 2006 Jan; 69(1):148-50. PubMed ID: 16441089
    [Abstract] [Full Text] [Related]

  • 3. Microtubule binding and disruption and induction of premature senescence by disorazole C(1).
    Tierno MB, Kitchens CA, Petrik B, Graham TH, Wipf P, Xu FL, Saunders WS, Raccor BS, Balachandran R, Day BW, Stout JR, Walczak CE, Ducruet AP, Reese CE, Lazo JS.
    J Pharmacol Exp Ther; 2009 Mar; 328(3):715-22. PubMed ID: 19066338
    [Abstract] [Full Text] [Related]

  • 4. Tanshinone IIA, an isolated compound from Salvia miltiorrhiza Bunge, induces apoptosis in HeLa cells through mitotic arrest.
    Zhou L, Chan WK, Xu N, Xiao K, Luo H, Luo KQ, Chang DC.
    Life Sci; 2008 Sep 12; 83(11-12):394-403. PubMed ID: 18721815
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents.
    Lai MJ, Kuo CC, Yeh TK, Hsieh HP, Chen LT, Pan WY, Hsu KY, Chang JY, Liou JP.
    ChemMedChem; 2009 Apr 12; 4(4):588-93. PubMed ID: 19266513
    [Abstract] [Full Text] [Related]

  • 6. Embelin derivatives and their anticancer activity through microtubule disassembly.
    Xu M, Cui J, Fu H, Proksch P, Lin W, Li M.
    Planta Med; 2005 Oct 12; 71(10):944-8. PubMed ID: 16254827
    [Abstract] [Full Text] [Related]

  • 7. Privileged structure-based quinazolinone natural product-templated libraries: identification of novel tubulin polymerization inhibitors.
    Liu JF, Wilson CJ, Ye P, Sprague K, Sargent K, Si Y, Beletsky G, Yohannes D, Ng SC.
    Bioorg Med Chem Lett; 2006 Feb 12; 16(3):686-90. PubMed ID: 16257201
    [Abstract] [Full Text] [Related]

  • 8. Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization.
    Feyen F, Cachoux F, Gertsch J, Wartmann M, Altmann KH.
    Acc Chem Res; 2008 Jan 12; 41(1):21-31. PubMed ID: 18159935
    [Abstract] [Full Text] [Related]

  • 9. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.
    Wu S, Guo Z, Hopkins CD, Wei N, Chu E, Wipf P, Schmitz JC.
    Oncotarget; 2015 Dec 01; 6(38):40866-79. PubMed ID: 26506423
    [Abstract] [Full Text] [Related]

  • 10. A novel isocoumarin derivative induces mitotic phase arrest and apoptosis of human multiple myeloma cells.
    Kawano T, Agata N, Kharbanda S, Avigan D, Kufe D.
    Cancer Chemother Pharmacol; 2007 Feb 01; 59(3):329-35. PubMed ID: 16830153
    [Abstract] [Full Text] [Related]

  • 11. 4'-Alkoxyl substitution enhancing the anti-mitotic effect of 5-(3',4',5'-substituted)anilino-4-hydroxy-8-nitroquinazolines as a novel class of anti-microtubule agents.
    Jin Y, Zhou ZY, Tian W, Yu Q, Long YQ.
    Bioorg Med Chem Lett; 2006 Nov 15; 16(22):5864-9. PubMed ID: 16942876
    [Abstract] [Full Text] [Related]

  • 12. Cytotoxic activity and cytostatic mechanism of novel 2-arylbenzo[b]furans.
    Yang H, Pang JY, Cai YC, Xu ZL, Xian LJ.
    J Pharm Pharmacol; 2006 Sep 15; 58(9):1281-7. PubMed ID: 16945188
    [Abstract] [Full Text] [Related]

  • 13. Microtubule-damaging agents enhance RASSF1A-induced cell death in lung cancer cell lines.
    Whang YM, Park KH, Jung HY, Jo UH, Kim YH.
    Cancer; 2009 Mar 15; 115(6):1253-66. PubMed ID: 19156899
    [Abstract] [Full Text] [Related]

  • 14. Antimitotic sulfonamides inhibit microtubule assembly dynamics and cancer cell proliferation.
    Mohan R, Banerjee M, Ray A, Manna T, Wilson L, Owa T, Bhattacharyya B, Panda D.
    Biochemistry; 2006 May 02; 45(17):5440-9. PubMed ID: 16634625
    [Abstract] [Full Text] [Related]

  • 15. Identifying a resistance determinant for the antimitotic natural products disorazole C1 and A1.
    Lazo JS, Reese CE, Vogt A, Vollmer LL, Kitchens CA, Günther E, Graham TH, Hopkins CD, Wipf P.
    J Pharmacol Exp Ther; 2010 Mar 02; 332(3):906-11. PubMed ID: 20008956
    [Abstract] [Full Text] [Related]

  • 16. 4'-methoxy-2-styrylchromone a novel microtubule-stabilizing antimitotic agent.
    Marinho J, Pedro M, Pinto DC, Silva AM, Cavaleiro JA, Sunkel CE, Nascimento MS.
    Biochem Pharmacol; 2008 Feb 15; 75(4):826-35. PubMed ID: 18036572
    [Abstract] [Full Text] [Related]

  • 17. Podoverine A--a novel microtubule destabilizing natural product from the Podophyllum species.
    Tran TT, Gerding-Reimers C, Schölermann B, Stanitzki B, Henkel T, Waldmann H, Ziegler S.
    Bioorg Med Chem; 2014 Sep 15; 22(18):5110-6. PubMed ID: 24530033
    [Abstract] [Full Text] [Related]

  • 18. Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.
    Gallet S, Flouquet N, Carato P, Pfeiffer B, Renard P, Léonce S, Pierré A, Berthelot P, Lebegue N.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1132-8. PubMed ID: 19162484
    [Abstract] [Full Text] [Related]

  • 19. 7-Diethylamino-3(2'-benzoxazolyl)-coumarin is a novel microtubule inhibitor with antimitotic activity in multidrug resistant cancer cells.
    Kim SN, Kim NH, Park YS, Kim H, Lee S, Wang Q, Kim YK.
    Biochem Pharmacol; 2009 Jun 15; 77(12):1773-9. PubMed ID: 19428332
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of aryloxazole derivatives as antimitotic and vascular-disrupting agents for cancer therapy.
    Choi MJ, No ES, Thorat DA, Jang JW, Yang H, Lee J, Choo H, Kim SJ, Lee CS, Ko SY, Lee J, Nam G, Pae AN.
    J Med Chem; 2013 Nov 27; 56(22):9008-18. PubMed ID: 24160376
    [Abstract] [Full Text] [Related]

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