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Journal Abstract Search

145 related items for PubMed ID: 1649498

  • 1. Imidazoquinoline derivatives: potent inhibitors of platelet cAMP phosphodiesterase which elevate cAMP levels and activate protein kinase in platelets.
    Seiler S, Gillespie E, Arnold AJ, Brassard CL, Meanwell NA, Fleming JS.
    Thromb Res; 1991 Apr; 62(1-2):31-42. PubMed ID: 1649498
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  • 2. Inhibitors of blood platelet cAMP phosphodiesterase. 2. Structure-activity relationships associated with 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones substituted with functionalized side chains.
    Meanwell NA, Pearce BC, Roth HR, Smith EC, Wedding DL, Wright JJ, Buchanan JO, Baryla UM, Gamberdella M, Gillespie E.
    J Med Chem; 1992 Jul 10; 35(14):2672-87. PubMed ID: 1321910
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  • 3. Activation of cyclic GMP-binding and cyclic AMP-specific phosphodiesterases of rat platelets by a mechanism involving cyclic AMP-dependent phosphorylation.
    Tremblay J, Lachance B, Hamet P.
    J Cyclic Nucleotide Protein Phosphor Res; 1985 Jul 10; 10(4):397-411. PubMed ID: 2411769
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  • 4. Y-590 (a new pyridazinone derivative), a potent anti-thrombotic agent--II. Inhibition of platelet phosphodiesterase.
    Mikashima H, Nakao T, Goto K, Ochi H, Yasuda H, Tsumagari T.
    Thromb Res; 1984 Sep 01; 35(5):589-94. PubMed ID: 6091293
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  • 5. Intact cell and cell-free phosphorylation and concomitant activation of a low Km, cAMP phosphodiesterase found in human platelets.
    Macphee CH, Reifsnyder DH, Moore TA, Beavo JA.
    J Cyclic Nucleotide Protein Phosphor Res; 1984 Sep 01; 11(7):487-96. PubMed ID: 2831258
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  • 6. Inhibition of human platelet cyclic AMP phosphodiesterase and of platelet aggregation by a hemisynthetic flavonoid, amentoflavone hexaacetate.
    Beretz A, Briançon-Scheid F, Stierlé A, Corre G, Anton R, Cazenave JP.
    Biochem Pharmacol; 1986 Jan 15; 35(2):257-62. PubMed ID: 3002388
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  • 7. Selective inhibitor of platelet cyclic adenosine monophosphate phosphodiesterase, cilostamide, inhibits platelet aggregation.
    Hidaka H, Hayashi H, Kohri H, Kimura Y, Hosokawa T, Igawa T, Saitoh Y.
    J Pharmacol Exp Ther; 1979 Oct 15; 211(1):26-30. PubMed ID: 226672
    [No Abstract] [Full Text] [Related]

  • 8. Antithrombotic activity of BMY-43351, a new imidazoquinoline with enhanced aqueous solubility.
    Fleming JS, Buchanan JO, Seiler SM, Meanwell NA.
    Thromb Res; 1991 Jul 01; 63(1):145-55. PubMed ID: 1948816
    [Abstract] [Full Text] [Related]

  • 9. 7-Bromo-1,5-dihydro-3,6-dimethylimidazo[2,1-b]quinazolin-2(3H)- one (Ro 15-2041), a potent antithrombotic agent that selectively inhibits platelet cyclic AMP-phosphodiesterase.
    Muggli R, Tschopp TB, Mittelholzer E, Baumgartner HR.
    J Pharmacol Exp Ther; 1985 Oct 01; 235(1):212-9. PubMed ID: 2995647
    [Abstract] [Full Text] [Related]

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  • 11. 2-Aminochromones block human platelet aggregation by inhibiting cyclic AMP-dependent phosphodiesterase leading to reduced platelet phospholipase C activity.
    Benjamin CW, Lin AH, Morris J, Wishka DG, Gorman RR.
    J Pharmacol Exp Ther; 1993 Apr 01; 265(1):457-62. PubMed ID: 7682615
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  • 14. Phosphorylation results in activation of a cAMP phosphodiesterase in human platelets.
    Macphee CH, Reifsnyder DH, Moore TA, Lerea KM, Beavo JA.
    J Biol Chem; 1988 Jul 25; 263(21):10353-8. PubMed ID: 2839485
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  • 16. Subcellular distribution of high-affinity type IV cyclic AMP phosphodiesterase activity in rabbit ventricular myocardium: relations to the effects of cardiotonic drugs.
    Kithas PA, Artman M, Thompson WJ, Strada SJ.
    Circ Res; 1988 Apr 25; 62(4):782-9. PubMed ID: 2832097
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