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Journal Abstract Search

368 related items for PubMed ID: 16501004

  • 1. OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker.
    Nakagomi-Hagihara R, Nakai D, Kawai K, Yoshigae Y, Tokui T, Abe T, Ikeda T.
    Drug Metab Dispos; 2006 May; 34(5):862-9. PubMed ID: 16501004
    [Abstract] [Full Text] [Related]

  • 2. Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
    Yamada A, Maeda K, Kamiyama E, Sugiyama D, Kondo T, Shiroyanagi Y, Nakazawa H, Okano T, Adachi M, Schuetz JD, Adachi Y, Hu Z, Kusuhara H, Sugiyama Y.
    Drug Metab Dispos; 2007 Dec; 35(12):2166-76. PubMed ID: 17823233
    [Abstract] [Full Text] [Related]

  • 3. Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans.
    Yamashiro W, Maeda K, Hirouchi M, Adachi Y, Hu Z, Sugiyama Y.
    Drug Metab Dispos; 2006 Jul; 34(7):1247-54. PubMed ID: 16624871
    [Abstract] [Full Text] [Related]

  • 4. Vectorial transport of enalapril by Oatp1a1/Mrp2 and OATP1B1 and OATP1B3/MRP2 in rat and human livers.
    Liu L, Cui Y, Chung AY, Shitara Y, Sugiyama Y, Keppler D, Pang KS.
    J Pharmacol Exp Ther; 2006 Jul; 318(1):395-402. PubMed ID: 16627748
    [Abstract] [Full Text] [Related]

  • 5. Transport mechanisms of hepatic uptake and bile excretion in clinical hepatobiliary scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan.
    Kobayashi M, Nakanishi T, Nishi K, Higaki Y, Okudaira H, Ono M, Tsujiuchi T, Mizutani A, Nishii R, Tamai I, Arano Y, Kawai K.
    Nucl Med Biol; 2014 Apr; 41(4):338-42. PubMed ID: 24607436
    [Abstract] [Full Text] [Related]

  • 6. Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.
    Ishiguro N, Maeda K, Saito A, Kishimoto W, Matsushima S, Ebner T, Roth W, Igarashi T, Sugiyama Y.
    Drug Metab Dispos; 2008 Apr; 36(4):796-805. PubMed ID: 18180273
    [Abstract] [Full Text] [Related]

  • 7. Predominant contribution of OATP1B3 to the hepatic uptake of telmisartan, an angiotensin II receptor antagonist, in humans.
    Ishiguro N, Maeda K, Kishimoto W, Saito A, Harada A, Ebner T, Roth W, Igarashi T, Sugiyama Y.
    Drug Metab Dispos; 2006 Jul; 34(7):1109-15. PubMed ID: 16611857
    [Abstract] [Full Text] [Related]

  • 8. Identification of the transporters involved in the hepatobiliary transport and intestinal efflux of methyl 1-(3,4-dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) glucuronide, a pharmacologically active metabolite of S-8921.
    Sakamoto S, Kusuhara H, Horie K, Takahashi K, Baba T, Ishizaki J, Sugiyama Y.
    Drug Metab Dispos; 2008 Aug; 36(8):1553-61. PubMed ID: 18474677
    [Abstract] [Full Text] [Related]

  • 9. Interaction of digitalis-like compounds with liver uptake transporters NTCP, OATP1B1, and OATP1B3.
    Gozalpour E, Greupink R, Wortelboer HM, Bilos A, Schreurs M, Russel FG, Koenderink JB.
    Mol Pharm; 2014 Jun 02; 11(6):1844-55. PubMed ID: 24754247
    [Abstract] [Full Text] [Related]

  • 10. Hepatic uptake and excretion of (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide (YM758), a novel if channel inhibitor, in rats and humans.
    Umehara K, Iwai M, Adachi Y, Iwatsubo T, Usui T, Kamimura H.
    Drug Metab Dispos; 2008 Jun 02; 36(6):1030-8. PubMed ID: 18332079
    [Abstract] [Full Text] [Related]

  • 11. Characterization of hepatobiliary transport systems of a novel alpha4beta1/alpha4beta7 dual antagonist, TR-14035.
    Tsuda-Tsukimoto M, Maeda T, Iwanaga T, Kume T, Tamai I.
    Pharm Res; 2006 Nov 02; 23(11):2646-56. PubMed ID: 16969695
    [Abstract] [Full Text] [Related]

  • 12. Role of transporters in the disposition of the selective phosphodiesterase-4 inhibitor (+)-2-[4-({[2-(benzo[1,3]dioxol-5-yloxy)-pyridine-3-carbonyl]-amino}-methyl)-3-fluoro-phenoxy]-propionic acid in rat and human.
    Kalgutkar AS, Feng B, Nguyen HT, Frederick KS, Campbell SD, Hatch HL, Bi YA, Kazolias DC, Davidson RE, Mireles RJ, Duignan DB, Choo EF, Zhao SX.
    Drug Metab Dispos; 2007 Nov 02; 35(11):2111-8. PubMed ID: 17686907
    [Abstract] [Full Text] [Related]

  • 13. Further characterization of the electrogenicity and pH sensitivity of the human organic anion-transporting polypeptides OATP1B1 and OATP1B3.
    Martinez-Becerra P, Briz O, Romero MR, Macias RI, Perez MJ, Sancho-Mateo C, Lostao MP, Fernandez-Abalos JM, Marin JJ.
    Mol Pharmacol; 2011 Mar 02; 79(3):596-607. PubMed ID: 21173039
    [Abstract] [Full Text] [Related]

  • 14. Evaluation of the endothelin receptor antagonists ambrisentan, bosentan, macitentan, and sitaxsentan as hepatobiliary transporter inhibitors and substrates in sandwich-cultured human hepatocytes.
    Lepist EI, Gillies H, Smith W, Hao J, Hubert C, St Claire RL, Brouwer KR, Ray AS.
    PLoS One; 2014 Mar 02; 9(1):e87548. PubMed ID: 24498134
    [Abstract] [Full Text] [Related]

  • 15. Transporter studies with the 3-O-sulfate conjugate of 17alpha-ethinylestradiol: assessment of human liver drug transporters.
    Han YH, Busler D, Hong Y, Tian Y, Chen C, Rodrigues AD.
    Drug Metab Dispos; 2010 Jul 02; 38(7):1072-82. PubMed ID: 20360302
    [Abstract] [Full Text] [Related]

  • 16. Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.
    Kunze A, Huwyler J, Camenisch G, Poller B.
    Drug Metab Dispos; 2014 Sep 02; 42(9):1514-21. PubMed ID: 24989890
    [Abstract] [Full Text] [Related]

  • 17. The roles of MRP2, MRP3, OATP1B1, and OATP1B3 in conjugated hyperbilirubinemia.
    Keppler D.
    Drug Metab Dispos; 2014 Apr 02; 42(4):561-5. PubMed ID: 24459177
    [Abstract] [Full Text] [Related]

  • 18. Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.
    Noé J, Portmann R, Brun ME, Funk C.
    Drug Metab Dispos; 2007 Aug 02; 35(8):1308-14. PubMed ID: 17470528
    [Abstract] [Full Text] [Related]

  • 19. Prediction of pharmacokinetic profile of valsartan in humans based on in vitro uptake-transport data.
    Poirier A, Cascais AC, Funk C, Lavé T.
    Chem Biodivers; 2009 Nov 02; 6(11):1975-87. PubMed ID: 19937834
    [Abstract] [Full Text] [Related]

  • 20. Transporters involved in the hepatic uptake of (99m)Tc-mebrofenin and indocyanine green.
    de Graaf W, Häusler S, Heger M, van Ginhoven TM, van Cappellen G, Bennink RJ, Kullak-Ublick GA, Hesselmann R, van Gulik TM, Stieger B.
    J Hepatol; 2011 Apr 02; 54(4):738-45. PubMed ID: 21163547
    [Abstract] [Full Text] [Related]

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