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Journal Abstract Search

237 related items for PubMed ID: 16503144

  • 21. Design, synthesis, and antiviral evaluation of purine-β-lactam and purine-aminopropanol hybrids.
    D'hooghe M, Mollet K, De Vreese R, Jonckers TH, Dams G, De Kimpe N.
    J Med Chem; 2012 Jun 14; 55(11):5637-41. PubMed ID: 22519297
    [Abstract] [Full Text] [Related]

  • 22. Rationally designed high-affinity 2-amino-6-halopurine heat shock protein 90 inhibitors that exhibit potent antitumor activity.
    Kasibhatla SR, Hong K, Biamonte MA, Busch DJ, Karjian PL, Sensintaffar JL, Kamal A, Lough RE, Brekken J, Lundgren K, Grecko R, Timony GA, Ran Y, Mansfield R, Fritz LC, Ulm E, Burrows FJ, Boehm MF.
    J Med Chem; 2007 Jun 14; 50(12):2767-78. PubMed ID: 17488003
    [Abstract] [Full Text] [Related]

  • 23. 7-Arylpiperazinylalkyl and 7-tetrahydroisoquinolinylalkyl derivatives of 8-alkoxy-purine-2,6-dione and some of their purine-2,6,8-trione analogs as 5-HT(1A), 5-HT(2A), and 5-HT(7) serotonin receptor ligands.
    Chłoń-Rzepa G, Zmudzki P, Zajdel P, Bojarski AJ, Duszyńska B, Nikiforuk A, Tatarczyńska E, Pawłowski M.
    Bioorg Med Chem; 2007 Aug 01; 15(15):5239-50. PubMed ID: 17517514
    [Abstract] [Full Text] [Related]

  • 24. Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase.
    Chang YT, Choi G, Bae YS, Burdett M, Moon HS, Lee JW, Gray NS, Schultz PG, Meijer L, Chung SK, Choi KY, Suh PG, Ryu SH.
    Chembiochem; 2002 Sep 02; 3(9):897-901. PubMed ID: 12210991
    [No Abstract] [Full Text] [Related]

  • 25. 2,6,9-trisubstituted purines: optimization towards highly potent and selective CDK1 inhibitors.
    Imbach P, Capraro HG, Furet P, Mett H, Meyer T, Zimmermann J.
    Bioorg Med Chem Lett; 1999 Jan 04; 9(1):91-6. PubMed ID: 9990463
    [Abstract] [Full Text] [Related]

  • 26. 2-anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1.
    Blanchard S, Soh CK, Lee CP, Poulsen A, Bonday Z, Goh KL, Goh KC, Goh MK, Pasha MK, Wang H, Williams M, Wood JM, Ethirajulu K, Dymock BW.
    Bioorg Med Chem Lett; 2012 Apr 15; 22(8):2880-4. PubMed ID: 22437109
    [Abstract] [Full Text] [Related]

  • 27. Preparation of a fully substituted purine library.
    Yang J, Dang Q, Liu J, Wei Z, Wu J, Bai X.
    J Comb Chem; 2005 Apr 15; 7(3):474-82. PubMed ID: 15877476
    [Abstract] [Full Text] [Related]

  • 28. SAR studies of 9-norbornylpurines as Coxsackievirus B3 inhibitors.
    Sála M, De Palma AM, Hřebabecký H, Dejmek M, Dračínský M, Leyssen P, Neyts J, Mertlíková-Kaiserová H, Nencka R.
    Bioorg Med Chem Lett; 2011 Jul 15; 21(14):4271-5. PubMed ID: 21684160
    [Abstract] [Full Text] [Related]

  • 29. The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.
    Hsieh JF, Wu SH, Yang YL, Choong KF, Chen ST.
    Bioorg Med Chem; 2007 May 15; 15(10):3450-6. PubMed ID: 17379526
    [Abstract] [Full Text] [Related]

  • 30. Synthesis and evaluation of a new series of substituted acyl(thio)urea and thiadiazolo [2,3-a] pyrimidine derivatives as potent inhibitors of influenza virus neuraminidase.
    Sun C, Zhang X, Huang H, Zhou P.
    Bioorg Med Chem; 2006 Dec 15; 14(24):8574-81. PubMed ID: 16979342
    [Abstract] [Full Text] [Related]

  • 31. Determining the structural basis for specificity of ligands using crystallographic screening.
    de Azevedo WF, Canduri F, Basso LA, Palma MS, Santos DS.
    Cell Biochem Biophys; 2006 Dec 15; 44(3):405-11. PubMed ID: 16679527
    [Abstract] [Full Text] [Related]

  • 32. Rapid evolution of 6-phenylpurine inhibitors of protein kinase B through structure-based design.
    Donald A, McHardy T, Rowlands MG, Hunter LJ, Davies TG, Berdini V, Boyle RG, Aherne GW, Garrett MD, Collins I.
    J Med Chem; 2007 May 17; 50(10):2289-92. PubMed ID: 17451235
    [Abstract] [Full Text] [Related]

  • 33. Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle.
    Lim HS, Archer CT, Kim YC, Hutchens T, Kodadek T.
    Chem Commun (Camb); 2008 Mar 07; (9):1064-6. PubMed ID: 18292891
    [Abstract] [Full Text] [Related]

  • 34. Pleuromutilin derivatives having a purine ring. Part 1: new compounds with promising antibacterial activity against resistant Gram-positive pathogens.
    Hirokawa Y, Kinoshita H, Tanaka T, Nakamura T, Fujimoto K, Kashimoto S, Kojima T, Kato S.
    Bioorg Med Chem Lett; 2008 Jun 15; 18(12):3556-61. PubMed ID: 18511280
    [Abstract] [Full Text] [Related]

  • 35. Synthesis and biological evaluation of purine-containing butenolides.
    Hakimelahi GH, Mei NW, Moosavi-Movahedi AA, Davari H, Hakimelahi S, King KY, Hwu JR, Wen YS.
    J Med Chem; 2001 May 24; 44(11):1749-57. PubMed ID: 11356110
    [Abstract] [Full Text] [Related]

  • 36. Utilization of 1,3-Dioxolanes in the Synthesis of α-branched Alkyl and Aryl 9-[2-(Phosphonomethoxy)Ethyl]Purines and Study of the Influence of α-branched Substitution for Potential Biological Activity.
    Pomeisl K, Pohl R, Snoeck R, Andrei G, Krečmerová M.
    Nucleosides Nucleotides Nucleic Acids; 2019 May 24; 38(2):119-156. PubMed ID: 30526265
    [Abstract] [Full Text] [Related]

  • 37. 6-substituted purines as inhibitors of 15-lipoxygenase; a structure-activity study.
    Bråthe A, Gundersen LL, Malterud KE, Rise F.
    Arch Pharm (Weinheim); 2005 Apr 24; 338(4):159-66. PubMed ID: 15864785
    [Abstract] [Full Text] [Related]

  • 38. Natural compounds as a source of protein tyrosine phosphatase inhibitors: application to the rational design of small-molecule derivatives.
    Ferreira CV, Justo GZ, Souza AC, Queiroz KC, Zambuzzi WF, Aoyama H, Peppelenbosch MP.
    Biochimie; 2006 Dec 24; 88(12):1859-73. PubMed ID: 17010496
    [Abstract] [Full Text] [Related]

  • 39. Novel N9-arenethenyl purines as potent dual Src/Abl tyrosine kinase inhibitors.
    Wang Y, Shakespeare WC, Huang WS, Sundaramoorthi R, Lentini S, Das S, Liu S, Banda G, Wen D, Zhu X, Xu Q, Keats J, Wang F, Wardwell S, Ning Y, Snodgrass JT, Broudy MI, Russian K, Dalgarno D, Clackson T, Sawyer TK.
    Bioorg Med Chem Lett; 2008 Sep 01; 18(17):4907-12. PubMed ID: 18691885
    [Abstract] [Full Text] [Related]

  • 40. Discovery of a novel series of inhibitors of human cytomegalovirus primase.
    Cushing TD, Adrian J, Chen X, DiMaio H, Doughan B, Flygare J, Liang L, Mayorga V, Miao S, Mellon H, Peterson MG, Powers JP, Spector F, Stein C, Wright M, Xu D, Ye Q, Jaen J.
    Bioorg Med Chem Lett; 2006 Sep 15; 16(18):4879-83. PubMed ID: 16814545
    [Abstract] [Full Text] [Related]

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