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Journal Abstract Search

330 related items for PubMed ID: 16507547

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  • 3. The anaesthetised methoxamine-sensitised rabbit model of torsades de pointes.
    Carlsson L.
    Pharmacol Ther; 2008 Aug; 119(2):160-7. PubMed ID: 18558435
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  • 4. Preclinical Torsades-de-Pointes screens: advantages and limitations of surrogate and direct approaches in evaluating proarrhythmic risk.
    Gintant GA.
    Pharmacol Ther; 2008 Aug; 119(2):199-209. PubMed ID: 18621077
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  • 5. Torsades de pointes liability inter-model comparisons: the experience of the QT PRODACT initiative.
    Hashimoto K.
    Pharmacol Ther; 2008 Aug; 119(2):195-8. PubMed ID: 18486227
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  • 7. Juvenile animal toxicity study designs to support pediatric drug development.
    Cappon GD, Bailey GP, Buschmann J, Feuston MH, Fisher JE, Hew KW, Hoberman AM, Ooshima Y, Stump DG, Hurtt ME.
    Birth Defects Res B Dev Reprod Toxicol; 2009 Dec; 86(6):463-9. PubMed ID: 20025047
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  • 8. Early clinical development: evaluation of drug-induced torsades de pointes risk.
    Vik T, Pollard C, Sager P.
    Pharmacol Ther; 2008 Aug; 119(2):210-4. PubMed ID: 18601950
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  • 9. Evaluations of organ system development in juvenile toxicology testing.
    Robinson K.
    Reprod Toxicol; 2008 Sep; 26(1):51-3. PubMed ID: 18595655
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  • 10. Perception of validity of clinical and preclinical methods for assessment of torsades de pointes liability.
    Pugsley MK, Hancox JC, Curtis MJ.
    Pharmacol Ther; 2008 Aug; 119(2):115-7. PubMed ID: 18590766
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  • 11. Safety evaluation to support First-In-Man investigations I: kinetic and safety pharmacology studies.
    Baldrick P.
    Regul Toxicol Pharmacol; 2008 Jul; 51(2):230-6. PubMed ID: 18501489
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  • 14. Use of the rabbit with a failing heart to test for torsadogenicity.
    Hamlin RL, Kijtawornrat A.
    Pharmacol Ther; 2008 Aug; 119(2):179-85. PubMed ID: 18691764
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  • 15. Real life juvenile toxicity case studies: the good, the bad and the ugly.
    De Schaepdrijver L, Rouan MC, Raoof A, Bailey GP, De Zwart L, Monbaliu J, Coogan TP, Lammens L, Coussement W.
    Reprod Toxicol; 2008 Sep; 26(1):54-5. PubMed ID: 18514481
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  • 17. [Methodological characteristics of the preclinical study of the safety of drug preparations for children].
    Mal'tseva LF, Muratova GP, Motovilova VG, Sirinova NA.
    Farmakol Toksikol; 1988 Sep; 51(4):96-100. PubMed ID: 3191987
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  • 18. What have we learned from pre-clinical juvenile toxicity studies?
    Bailey GP, Mariën D.
    Reprod Toxicol; 2009 Sep; 28(2):226-9. PubMed ID: 19446432
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  • 19. Supplemental studies for cardiovascular risk assessment in safety pharmacology: a critical overview.
    Picard S, Goineau S, Guillaume P, Henry J, Hanouz JL, Rouet R.
    Cardiovasc Toxicol; 2011 Dec; 11(4):285-307. PubMed ID: 21805209
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  • 20. Optimising the design of preliminary toxicity studies for pharmaceutical safety testing in the dog.
    Smith D, Combes R, Depelchin O, Jacobsen SD, Hack R, Luft J, Lammens L, von Landenberg F, Phillips B, Pfister R, Rabemampianina Y, Sparrow S, Stark C, Stephan-Gueldner M.
    Regul Toxicol Pharmacol; 2005 Mar; 41(2):95-101. PubMed ID: 15698532
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