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Journal Abstract Search


464 related items for PubMed ID: 16510126

  • 1. Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes.
    Narimatsu S, Yonemoto R, Saito K, Takaya K, Kumamoto T, Ishikawa T, Asanuma M, Funada M, Kiryu K, Naito S, Yoshida Y, Yamamoto S, Hanioka N.
    Biochem Pharmacol; 2006 Apr 28; 71(9):1377-85. PubMed ID: 16510126
    [Abstract] [Full Text] [Related]

  • 2. Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes.
    Narimatsu S, Yonemoto R, Masuda K, Katsu T, Asanuma M, Kamata T, Katagi M, Tsuchihashi H, Kumamoto T, Ishikawa T, Naito S, Yamano S, Hanioka N.
    Biochem Pharmacol; 2008 Feb 01; 75(3):752-60. PubMed ID: 17980859
    [Abstract] [Full Text] [Related]

  • 3. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB, Surry D, Price RJ, Lake BG, Evans DC.
    Xenobiotica; 2000 Oct 01; 30(10):955-69. PubMed ID: 11315104
    [Abstract] [Full Text] [Related]

  • 4. Metabolism of the tryptamine-derived new psychoactive substances 5-MeO-2-Me-DALT, 5-MeO-2-Me-ALCHT, and 5-MeO-2-Me-DIPT and their detectability in urine studied by GC-MS, LC-MSn , and LC-HR-MS/MS.
    Caspar AT, Gaab JB, Michely JA, Brandt SD, Meyer MR, Maurer HH.
    Drug Test Anal; 2018 Jan 01; 10(1):184-195. PubMed ID: 28342193
    [Abstract] [Full Text] [Related]

  • 5. [O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.
    Rodrigues AD, Kukulka MJ, Roberts EM, Ouellet D, Rodgers TR.
    Drug Metab Dispos; 1996 Jan 01; 24(1):126-36. PubMed ID: 8825200
    [Abstract] [Full Text] [Related]

  • 6. Azelastine N-demethylation by cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in human liver microsomes: evaluation of approach to predict the contribution of multiple CYPs.
    Nakajima M, Nakamura S, Tokudome S, Shimada N, Yamazaki H, Yokoi T.
    Drug Metab Dispos; 1999 Dec 01; 27(12):1381-91. PubMed ID: 10570018
    [Abstract] [Full Text] [Related]

  • 7. The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2.
    Narimatsu S, Kiryu K, Yonemoto R, Yoshino M, Kobatake M, Kazamori D, Hagino S, Masuda K, Katsu T, Asanuma M, Kumamoto T, Ishikawa T, Funae Y, Yamano S, Hanioka N, Naito S.
    Chem Biol Interact; 2008 Mar 10; 172(1):11-21. PubMed ID: 18191824
    [Abstract] [Full Text] [Related]

  • 8. Elucidation of individual cytochrome P450 enzymes involved in the metabolism of clozapine.
    Fang J, Coutts RT, McKenna KF, Baker GB.
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Nov 10; 358(5):592-9. PubMed ID: 9840430
    [Abstract] [Full Text] [Related]

  • 9. Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily.
    Gorski JC, Jones DR, Wrighton SA, Hall SD.
    Biochem Pharmacol; 1994 Jul 05; 48(1):173-82. PubMed ID: 8043020
    [Abstract] [Full Text] [Related]

  • 10. Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol.
    Pan LP, Wijnant P, De Vriendt C, Rosseel MT, Belpaire FM.
    Br J Clin Pharmacol; 1997 Dec 05; 44(6):557-64. PubMed ID: 9431831
    [Abstract] [Full Text] [Related]

  • 11. Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes.
    Nakajima M, Inoue T, Shimada N, Tokudome S, Yamamoto T, Kuroiwa Y.
    Drug Metab Dispos; 1998 Mar 05; 26(3):261-6. PubMed ID: 9492390
    [Abstract] [Full Text] [Related]

  • 12. Reevaluation of the microsomal metabolism of montelukast: major contribution by CYP2C8 at clinically relevant concentrations.
    Filppula AM, Laitila J, Neuvonen PJ, Backman JT.
    Drug Metab Dispos; 2011 May 05; 39(5):904-11. PubMed ID: 21289076
    [Abstract] [Full Text] [Related]

  • 13. Human CYP2C19 is a major omeprazole 5-hydroxylase, as demonstrated with recombinant cytochrome P450 enzymes.
    Karam WG, Goldstein JA, Lasker JM, Ghanayem BI.
    Drug Metab Dispos; 1996 Oct 05; 24(10):1081-7. PubMed ID: 8894508
    [Abstract] [Full Text] [Related]

  • 14. Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.
    Yumibe N, Huie K, Chen KJ, Snow M, Clement RP, Cayen MN.
    Biochem Pharmacol; 1996 Jan 26; 51(2):165-72. PubMed ID: 8615885
    [Abstract] [Full Text] [Related]

  • 15. Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples.
    Yamazaki H, Inoue K, Shaw PM, Checovich WJ, Guengerich FP, Shimada T.
    J Pharmacol Exp Ther; 1997 Nov 26; 283(2):434-42. PubMed ID: 9353355
    [Abstract] [Full Text] [Related]

  • 16. Characterization of human cytochrome P450 enzymes involved in the metabolism of cyamemazine.
    Arbus C, Benyamina A, Llorca PM, Baylé F, Bromet N, Massiere F, Garay RP, Hameg A.
    Eur J Pharm Sci; 2007 Dec 26; 32(4-5):357-66. PubMed ID: 17951033
    [Abstract] [Full Text] [Related]

  • 17. Metabolism of the psychotomimetic tryptamine derivative 5-methoxy-N,N-diisopropyltryptamine in humans: identification and quantification of its urinary metabolites.
    Kamata T, Katagi M, Kamata HT, Miki A, Shima N, Zaitsu K, Nishikawa M, Tanaka E, Honda K, Tsuchihashi H.
    Drug Metab Dispos; 2006 Feb 26; 34(2):281-7. PubMed ID: 16280455
    [Abstract] [Full Text] [Related]

  • 18. Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.
    Hyland R, Roe EG, Jones BC, Smith DA.
    Br J Clin Pharmacol; 2001 Mar 26; 51(3):239-48. PubMed ID: 11298070
    [Abstract] [Full Text] [Related]

  • 19. Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation.
    Stresser DM, Kupfer D.
    Drug Metab Dispos; 1998 Sep 26; 26(9):868-74. PubMed ID: 9733665
    [Abstract] [Full Text] [Related]

  • 20. In vitro metabolism of nobiletin, a polymethoxy-flavonoid, by human liver microsomes and cytochrome P450.
    Koga N, Ohta C, Kato Y, Haraguchi K, Endo T, Ogawa K, Ohta H, Yano M.
    Xenobiotica; 2011 Nov 26; 41(11):927-33. PubMed ID: 21726170
    [Abstract] [Full Text] [Related]


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