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194 related items for PubMed ID: 16510762

  • 1. Therapeutic approach for diabetic nephropathy using gene delivery of translocase of inner mitochondrial membrane 44 by reducing mitochondrial superoxide production.
    Zhang Y, Wada J, Hashimoto I, Eguchi J, Yasuhara A, Kanwar YS, Shikata K, Makino H.
    J Am Soc Nephrol; 2006 Apr; 17(4):1090-101. PubMed ID: 16510762
    [Abstract] [Full Text] [Related]

  • 2. Gene delivery of Tim44 reduces mitochondrial superoxide production and ameliorates neointimal proliferation of injured carotid artery in diabetic rats.
    Matsuoka T, Wada J, Hashimoto I, Zhang Y, Eguchi J, Ogawa N, Shikata K, Kanwar YS, Makino H.
    Diabetes; 2005 Oct; 54(10):2882-90. PubMed ID: 16186389
    [Abstract] [Full Text] [Related]

  • 3. Mitochondrial superoxide plays a crucial role in the development of mitochondrial dysfunction during high glucose exposure in rat renal proximal tubular cells.
    Munusamy S, MacMillan-Crow LA.
    Free Radic Biol Med; 2009 Apr 15; 46(8):1149-57. PubMed ID: 19439219
    [Abstract] [Full Text] [Related]

  • 4. Functional consequences of thyroid hormone-induced changes in the mitochondrial protein import pathway.
    Colavecchia M, Christie LN, Kanwar YS, Hood DA.
    Am J Physiol Endocrinol Metab; 2003 Jan 15; 284(1):E29-35. PubMed ID: 12388124
    [Abstract] [Full Text] [Related]

  • 5. The mitochondrial protein import motor: dissociation of mitochondrial hsp70 from its membrane anchor requires ATP binding rather than ATP hydrolysis.
    Horst M, Oppliger W, Feifel B, Schatz G, Glick BS.
    Protein Sci; 1996 Apr 15; 5(4):759-67. PubMed ID: 8845766
    [Abstract] [Full Text] [Related]

  • 6. The nucleotide exchange factor MGE exerts a key function in the ATP-dependent cycle of mt-Hsp70-Tim44 interaction driving mitochondrial protein import.
    Schneider HC, Westermann B, Neupert W, Brunner M.
    EMBO J; 1996 Nov 01; 15(21):5796-803. PubMed ID: 8918457
    [Abstract] [Full Text] [Related]

  • 7. Translocase of inner mitochondrial membrane 44 alters the mitochondrial fusion and fission dynamics and protects from type 2 diabetes.
    Wang Y, Katayama A, Terami T, Han X, Nunoue T, Zhang D, Teshigawara S, Eguchi J, Nakatsuka A, Murakami K, Ogawa D, Furuta Y, Makino H, Wada J.
    Metabolism; 2015 Jun 01; 64(6):677-88. PubMed ID: 25749183
    [Abstract] [Full Text] [Related]

  • 8. Pam16 has an essential role in the mitochondrial protein import motor.
    Frazier AE, Dudek J, Guiard B, Voos W, Li Y, Lind M, Meisinger C, Geissler A, Sickmann A, Meyer HE, Bilanchone V, Cumsky MG, Truscott KN, Pfanner N, Rehling P.
    Nat Struct Mol Biol; 2004 Mar 01; 11(3):226-33. PubMed ID: 14981507
    [Abstract] [Full Text] [Related]

  • 9. Tim14, a novel key component of the import motor of the TIM23 protein translocase of mitochondria.
    Mokranjac D, Sichting M, Neupert W, Hell K.
    EMBO J; 2003 Oct 01; 22(19):4945-56. PubMed ID: 14517234
    [Abstract] [Full Text] [Related]

  • 10. Regulated cycling of mitochondrial Hsp70 at the protein import channel.
    Liu Q, D'Silva P, Walter W, Marszalek J, Craig EA.
    Science; 2003 Apr 04; 300(5616):139-41. PubMed ID: 12677068
    [Abstract] [Full Text] [Related]

  • 11. Identification of a fluorescent small-molecule enhancer for therapeutic autophagy in colorectal cancer by targeting mitochondrial protein translocase TIM44.
    Huang Y, Zhou J, Luo S, Wang Y, He J, Luo P, Chen Z, Liu T, Tan X, Ou J, Miao H, Liang H, Shi C.
    Gut; 2018 Feb 04; 67(2):307-319. PubMed ID: 27849558
    [Abstract] [Full Text] [Related]

  • 12. Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane.
    D'Silva P, Liu Q, Walter W, Craig EA.
    Nat Struct Mol Biol; 2004 Nov 04; 11(11):1084-91. PubMed ID: 15489862
    [Abstract] [Full Text] [Related]

  • 13. Structure of the human Tim44 C-terminal domain in complex with pentaethylene glycol: ligand-bound form.
    Handa N, Kishishita S, Morita S, Akasaka R, Jin Z, Chrzas J, Chen L, Liu ZJ, Wang BC, Sugano S, Tanaka A, Terada T, Shirouzu M, Yokoyama S.
    Acta Crystallogr D Biol Crystallogr; 2007 Dec 04; 63(Pt 12):1225-34. PubMed ID: 18084070
    [Abstract] [Full Text] [Related]

  • 14. The J domain-related cochaperone Tim16 is a constituent of the mitochondrial TIM23 preprotein translocase.
    Kozany C, Mokranjac D, Sichting M, Neupert W, Hell K.
    Nat Struct Mol Biol; 2004 Mar 04; 11(3):234-41. PubMed ID: 14981506
    [Abstract] [Full Text] [Related]

  • 15. Differential requirement for the mitochondrial Hsp70-Tim44 complex in unfolding and translocation of preproteins.
    Voos W, von Ahsen O, Müller H, Guiard B, Rassow J, Pfanner N.
    EMBO J; 1996 Jun 03; 15(11):2668-77. PubMed ID: 8654364
    [Abstract] [Full Text] [Related]

  • 16. Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor.
    van der Laan M, Chacinska A, Lind M, Perschil I, Sickmann A, Meyer HE, Guiard B, Meisinger C, Pfanner N, Rehling P.
    Mol Cell Biol; 2005 Sep 03; 25(17):7449-58. PubMed ID: 16107694
    [Abstract] [Full Text] [Related]

  • 17. Delivery of megsin siRNA plasmid reveals therapeutic potential against diabetic nephropathy by down-regulating p27(kip1) level.
    Liu M, Zhang Y, Chi Y, Zhai S, Wang B, Shi Y, Li Y.
    J Nephrol; 2012 Sep 03; 25(3):418-25. PubMed ID: 21928229
    [Abstract] [Full Text] [Related]

  • 18. A J-protein is an essential subunit of the presequence translocase-associated protein import motor of mitochondria.
    Truscott KN, Voos W, Frazier AE, Lind M, Li Y, Geissler A, Dudek J, Müller H, Sickmann A, Meyer HE, Meisinger C, Guiard B, Rehling P, Pfanner N.
    J Cell Biol; 2003 Nov 24; 163(4):707-13. PubMed ID: 14638855
    [Abstract] [Full Text] [Related]

  • 19. Mitochondrial protein import motor: the ATPase domain of matrix Hsp70 is crucial for binding to Tim44, while the peptide binding domain and the carboxy-terminal segment play a stimulatory role.
    Krimmer T, Rassow J, Kunau WH, Voos W, Pfanner N.
    Mol Cell Biol; 2000 Aug 24; 20(16):5879-87. PubMed ID: 10913171
    [Abstract] [Full Text] [Related]

  • 20. Mitochondrial protein import: molecular basis of the ATP-dependent interaction of MtHsp70 with Tim44.
    Moro F, Okamoto K, Donzeau M, Neupert W, Brunner M.
    J Biol Chem; 2002 Mar 01; 277(9):6874-80. PubMed ID: 11733493
    [Abstract] [Full Text] [Related]

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