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153 related items for PubMed ID: 1651082

  • 1. A redox reaction between MPP+ and MPDP+ to produce superoxide radicals does not impair mitochondrial function.
    Walker MJ, Jenner P, Marsden CD.
    Biochem Pharmacol; 1991 Jul 25; 42(4):913-9. PubMed ID: 1651082
    [Abstract] [Full Text] [Related]

  • 2. Toxicity of the 1-methyl-4-phenyl-2,3-dihydropyridinium and 1-methyl-4-phenylpyridinium species in primary cultures of mouse astrocytes.
    Wu EY, Langston JW, Di Monte DA.
    J Pharmacol Exp Ther; 1992 Jul 25; 262(1):225-30. PubMed ID: 1625201
    [Abstract] [Full Text] [Related]

  • 3. 1-Methyl-4-phenyl-2,3-dihydropyridinium is transformed by ubiquinone to the selective nigrostriatal toxin 1-methyl-4-phenylpyridinium.
    Shi H, Noguchi N, Xu Y, Niki E.
    FEBS Lett; 1999 Nov 19; 461(3):196-200. PubMed ID: 10567696
    [Abstract] [Full Text] [Related]

  • 4. Bioactivation of MPTP: reactive metabolites and possible biochemical sequelae.
    Trevor AJ, Castagnoli N, Caldera P, Ramsay RR, Singer TP.
    Life Sci; 1987 Feb 23; 40(8):713-9. PubMed ID: 3492651
    [Abstract] [Full Text] [Related]

  • 5. Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.
    Heikkila RE, Nicklas WJ, Vyas I, Duvoisin RC.
    Neurosci Lett; 1985 Dec 18; 62(3):389-94. PubMed ID: 3912685
    [Abstract] [Full Text] [Related]

  • 6. Preferential Extracellular Generation of the Active Parkinsonian Toxin MPP+ by Transporter-Independent Export of the Intermediate MPDP+.
    Schildknecht S, Pape R, Meiser J, Karreman C, Strittmatter T, Odermatt M, Cirri E, Friemel A, Ringwald M, Pasquarelli N, Ferger B, Brunner T, Marx A, Möller HM, Hiller K, Leist M.
    Antioxid Redox Signal; 2015 Nov 01; 23(13):1001-16. PubMed ID: 26413876
    [Abstract] [Full Text] [Related]

  • 7. Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.
    Vyas I, Heikkila RE, Nicklas WJ.
    J Neurochem; 1986 May 01; 46(5):1501-7. PubMed ID: 3485701
    [Abstract] [Full Text] [Related]

  • 8. MPTP, MPP+ and mitochondrial function.
    Nicklas WJ, Youngster SK, Kindt MV, Heikkila RE.
    Life Sci; 1987 Feb 23; 40(8):721-9. PubMed ID: 3100899
    [Abstract] [Full Text] [Related]

  • 9. EPR kinetic studies of superoxide radicals generated during the autoxidation of 1-methyl-4-phenyl-2,3-dihydropyridinium, a bioactivated intermediate of parkinsonian-inducing neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    Zang LY, Misra HP.
    J Biol Chem; 1992 Nov 25; 267(33):23601-8. PubMed ID: 1331093
    [Abstract] [Full Text] [Related]

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  • 13. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain.
    Mizuno Y, Sone N, Saitoh T.
    J Neurochem; 1987 Jun 25; 48(6):1787-93. PubMed ID: 3106573
    [Abstract] [Full Text] [Related]

  • 14. Comparative toxicity of MPTP, MPP+ and 3,3-dimethyl-MPDP+ to dopaminergic neurons of the rat substantia nigra.
    Sayre LM, Arora PK, Iacofano LA, Harik SI.
    Eur J Pharmacol; 1986 May 13; 124(1-2):171-4. PubMed ID: 3487462
    [Abstract] [Full Text] [Related]

  • 15. Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes.
    Di Monte D, Ekström G, Shinka T, Smith MT, Trevor AJ, Castagnoli N.
    Chem Biol Interact; 1987 May 13; 62(2):105-16. PubMed ID: 3496169
    [Abstract] [Full Text] [Related]

  • 16. Production and disposition of 1-methyl-4-phenylpyridinium in primary cultures of mouse astrocytes.
    Di Monte DA, Wu EY, Irwin I, Delanney LE, Langston JW.
    Glia; 1992 May 13; 5(1):48-55. PubMed ID: 1311704
    [Abstract] [Full Text] [Related]

  • 17. Comparative toxicity and antioxidant activity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its monoamine oxidase B-generated metabolites in isolated hepatocytes and liver microsomes.
    Ekström G, Di Monte D, Sandy MS, Smith MT.
    Arch Biochem Biophys; 1987 May 15; 255(1):14-8. PubMed ID: 3496045
    [Abstract] [Full Text] [Related]

  • 18. Mitochondrial and metabolic toxicity of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine.
    Kindt MV, Heikkila RE, Nicklas WJ.
    J Pharmacol Exp Ther; 1987 Sep 15; 242(3):858-63. PubMed ID: 3498818
    [Abstract] [Full Text] [Related]

  • 19. Involvement of hepatic aldehyde oxidase in conversion of 1-methyl-4-phenyl-2,3-dihydropyridinium (MPDP+) to 1-methyl-4-phenyl-5,6-dihydro-2-pyridone.
    Yoshihara S, Ohta S.
    Arch Biochem Biophys; 1998 Dec 01; 360(1):93-8. PubMed ID: 9826433
    [Abstract] [Full Text] [Related]

  • 20. Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO).
    Herraiz T, Arán VJ, Guillén H.
    Free Radic Res; 2009 Oct 01; 43(10):975-84. PubMed ID: 19669997
    [Abstract] [Full Text] [Related]

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