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223 related items for PubMed ID: 16515890

  • 1. Widespread correction of lysosomal storage in the mucopolysaccharidosis type VII mouse brain with a herpes simplex virus type 1 vector expressing beta-glucuronidase.
    Berges BK, Yellayi S, Karolewski BA, Miselis RR, Wolfe JH, Fraser NW.
    Mol Ther; 2006 May; 13(5):859-69. PubMed ID: 16515890
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  • 2. Significantly increased expression of beta-glucuronidase in the central nervous system of mucopolysaccharidosis type VII mice from the latency-associated transcript promoter in a nonpathogenic herpes simplex virus type 1 vector.
    Zhu J, Kang W, Wolfe JH, Fraser NW.
    Mol Ther; 2000 Jul; 2(1):82-94. PubMed ID: 10899831
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  • 3. Sustained production of beta-glucuronidase from localized sites after AAV vector gene transfer results in widespread distribution of enzyme and reversal of lysosomal storage lesions in a large volume of brain in mucopolysaccharidosis VII mice.
    Skorupa AF, Fisher KJ, Wilson JM, Parente MK, Wolfe JH.
    Exp Neurol; 1999 Nov; 160(1):17-27. PubMed ID: 10630187
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  • 4. High level expression and export of beta-glucuronidase from murine mucopolysaccharidosis VII cells corrected by a double-copy retrovirus vector.
    Wolfe JH, Kyle JW, Sands MS, Sly WS, Markowitz DG, Parente MK.
    Gene Ther; 1995 Jan; 2(1):70-8. PubMed ID: 7712336
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  • 5. Neonatal intramuscular injection with recombinant adeno-associated virus results in prolonged beta-glucuronidase expression in situ and correction of liver pathology in mucopolysaccharidosis type VII mice.
    Daly TM, Okuyama T, Vogler C, Haskins ME, Muzyczka N, Sands MS.
    Hum Gene Ther; 1999 Jan 01; 10(1):85-94. PubMed ID: 10022533
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  • 8. Genetic correction of the fetal brain increases the lifespan of mice with the severe multisystemic disease mucopolysaccharidosis type VII.
    Karolewski BA, Wolfe JH.
    Mol Ther; 2006 Jul 01; 14(1):14-24. PubMed ID: 16624622
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  • 11. Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse.
    Sferra TJ, Qu G, McNeely D, Rennard R, Clark KR, Lo WD, Johnson PR.
    Hum Gene Ther; 2000 Mar 01; 11(4):507-19. PubMed ID: 10724030
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  • 14. Decreased lysosomal storage in the adult MPS VII mouse brain in the vicinity of grafts of retroviral vector-corrected fibroblasts secreting high levels of beta-glucuronidase.
    Taylor RM, Wolfe JH.
    Nat Med; 1997 Jul 01; 3(7):771-4. PubMed ID: 9212105
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  • 16. Cloning of the canine beta-glucuronidase cDNA, mutation identification in canine MPS VII, and retroviral vector-mediated correction of MPS VII cells.
    Ray J, Bouvet A, DeSanto C, Fyfe JC, Xu D, Wolfe JH, Aguirre GD, Patterson DF, Haskins ME, Henthorn PS.
    Genomics; 1998 Mar 01; 48(2):248-53. PubMed ID: 9521879
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  • 17. Long-term AAV vector gene and protein expression in mouse brain from a small pan-cellular promoter is similar to neural cell promoters.
    Husain T, Passini MA, Parente MK, Fraser NW, Wolfe JH.
    Gene Ther; 2009 Jul 01; 16(7):927-32. PubMed ID: 19458648
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  • 18. Long-term and significant correction of brain lesions in adult mucopolysaccharidosis type VII mice using recombinant AAV vectors.
    Bosch A, Perret E, Desmaris N, Heard JM.
    Mol Ther; 2000 Jan 01; 1(1):63-70. PubMed ID: 10933913
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  • 19. Systemic hyperosmolality improves beta-glucuronidase distribution and pathology in murine MPS VII brain following intraventricular gene transfer.
    Ghodsi A, Stein C, Derksen T, Martins I, Anderson RD, Davidson BL.
    Exp Neurol; 1999 Nov 01; 160(1):109-16. PubMed ID: 10630195
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  • 20. Transgene produces massive overexpression of human beta -glucuronidase in mice, lysosomal storage of enzyme, and strain-dependent tumors.
    Vogler C, Galvin N, Levy B, Grubb J, Jiang J, Zhou XY, Sly WS.
    Proc Natl Acad Sci U S A; 2003 Mar 04; 100(5):2669-73. PubMed ID: 12591953
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