These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

140 related items for PubMed ID: 16518418

  • 1. Potentiation of irinotecan sensitivity by Se-methylselenocysteine in an in vivo tumor model is associated with downregulation of cyclooxygenase-2, inducible nitric oxide synthase, and hypoxia-inducible factor 1alpha expression, resulting in reduced angiogenesis.
    Yin MB, Li ZR, Tóth K, Cao S, Durrani FA, Hapke G, Bhattacharya A, Azrak RG, Frank C, Rustum YM.
    Oncogene; 2006 Apr 20; 25(17):2509-19. PubMed ID: 16518418
    [Abstract] [Full Text] [Related]

  • 2. Se-methylselenocysteine sensitizes hypoxic tumor cells to irinotecan by targeting hypoxia-inducible factor 1alpha.
    Chintala S, Tóth K, Cao S, Durrani FA, Vaughan MM, Jensen RL, Rustum YM.
    Cancer Chemother Pharmacol; 2010 Oct 20; 66(5):899-911. PubMed ID: 20066420
    [Abstract] [Full Text] [Related]

  • 3. Irinotecan pharmacokinetic and pharmacogenomic alterations induced by methylselenocysteine in human head and neck xenograft tumors.
    Azrak RG, Yu J, Pendyala L, Smith PF, Cao S, Li X, Shannon WD, Durrani FA, McLeod HL, Rustum YM.
    Mol Cancer Ther; 2005 May 20; 4(5):843-54. PubMed ID: 15897249
    [Abstract] [Full Text] [Related]

  • 4. Hypoxia-specific drug tirapazamine does not abrogate hypoxic tumor cells in combination therapy with irinotecan and methylselenocysteine in well-differentiated human head and neck squamous cell carcinoma a253 xenografts.
    Bhattacharya A, Tóth K, Durrani FA, Cao S, Slocum HK, Chintala S, Rustum YM.
    Neoplasia; 2008 Aug 20; 10(8):857-65. PubMed ID: 18670644
    [Abstract] [Full Text] [Related]

  • 5. Enhanced 7-ethyl-10-hydroxycamptothecin (SN-38) lethality by methylselenocysteine is associated with Chk2 phosphorylation at threonine-68 and down-regulation of Cdc6 expression.
    Yin MB, Li ZR, Cao S, Durrani FA, Azrak RG, Frank C, Rustum YM.
    Mol Pharmacol; 2004 Jul 20; 66(1):153-60. PubMed ID: 15213307
    [Abstract] [Full Text] [Related]

  • 6. Tumor vascular maturation and improved drug delivery induced by methylselenocysteine leads to therapeutic synergy with anticancer drugs.
    Bhattacharya A, Seshadri M, Oven SD, Tóth K, Vaughan MM, Rustum YM.
    Clin Cancer Res; 2008 Jun 15; 14(12):3926-32. PubMed ID: 18559614
    [Abstract] [Full Text] [Related]

  • 7. Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.
    Cao S, Durrani FA, Rustum YM.
    Clin Cancer Res; 2004 Apr 01; 10(7):2561-9. PubMed ID: 15073137
    [Abstract] [Full Text] [Related]

  • 8. Efficacy of increasing the therapeutic index of irinotecan, plasma and tissue selenium concentrations is methylselenocysteine dose dependent.
    Azrak RG, Cao S, Pendyala L, Durrani FA, Fakih M, Combs GF, Prey J, Smith PF, Rustum YM.
    Biochem Pharmacol; 2007 May 01; 73(9):1280-7. PubMed ID: 17239826
    [Abstract] [Full Text] [Related]

  • 9. Overexpression of Bax enhances antitumor activity of chemotherapeutic agents in human head and neck squamous cell carcinoma.
    Guo B, Cao S, Tóth K, Azrak RG, Rustum YM.
    Clin Cancer Res; 2000 Feb 01; 6(2):718-24. PubMed ID: 10690558
    [Abstract] [Full Text] [Related]

  • 10. Augmented therapeutic efficacy of irinotecan is associated with enhanced drug accumulation.
    Azrak RG, Cao S, Durrani FA, Toth K, Bhattacharya A, Rustum YM.
    Cancer Lett; 2011 Dec 08; 311(2):219-29. PubMed ID: 21872389
    [Abstract] [Full Text] [Related]

  • 11. Lack of microvessels in well-differentiated regions of human head and neck squamous cell carcinoma A253 associated with functional magnetic resonance imaging detectable hypoxia, limited drug delivery, and resistance to irinotecan therapy.
    Bhattacharya A, Tóth K, Mazurchuk R, Spernyak JA, Slocum HK, Pendyala L, Azrak R, Cao S, Durrani FA, Rustum YM.
    Clin Cancer Res; 2004 Dec 01; 10(23):8005-17. PubMed ID: 15585636
    [Abstract] [Full Text] [Related]

  • 12. Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.
    Fakih M, Cao S, Durrani FA, Rustum YM.
    Clin Colorectal Cancer; 2005 Jul 01; 5(2):132-5. PubMed ID: 16098255
    [Abstract] [Full Text] [Related]

  • 13. Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis.
    Pencreach E, Guérin E, Nicolet C, Lelong-Rebel I, Voegeli AC, Oudet P, Larsen AK, Gaub MP, Guenot D.
    Clin Cancer Res; 2009 Feb 15; 15(4):1297-307. PubMed ID: 19190131
    [Abstract] [Full Text] [Related]

  • 14. Se-methylselenocysteine offers selective protection against toxicity and potentiates the antitumour activity of anticancer drugs in preclinical animal models.
    Cao S, Durrani FA, Tóth K, Rustum YM.
    Br J Cancer; 2014 Apr 02; 110(7):1733-43. PubMed ID: 24619073
    [Abstract] [Full Text] [Related]

  • 15. Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis.
    Li Z, Carrier L, Belame A, Thiyagarajah A, Salvo VA, Burow ME, Rowan BG.
    Breast Cancer Res Treat; 2009 Nov 02; 118(1):33-43. PubMed ID: 18855134
    [Abstract] [Full Text] [Related]

  • 16. Se-methylselenocysteine inhibits lipopolysaccharide-induced NF-κB activation and iNOS induction in RAW 264.7 murine macrophages.
    Pan MH, Hong HM, Lin CL, Jhang AZ, Tsai JH, Badmaev V, Nagabhushanam K, Ho CT, Chen WJ.
    Mol Nutr Food Res; 2011 May 02; 55(5):723-32. PubMed ID: 21213327
    [Abstract] [Full Text] [Related]

  • 17. RNA interference-mediated downregulation of hypoxia-inducible factor-1α inhibits angiogenesis and survival of oral squamous cell carcinoma in vitro and in vivo.
    Zhou H, Fei W, Bai Y, Zhu S, Luo E, Chen K, Hu J.
    Eur J Cancer Prev; 2012 May 02; 21(3):289-99. PubMed ID: 22113109
    [Abstract] [Full Text] [Related]

  • 18. Effects of quercetin combined with anticancer drugs on metastasis-associated factors of gastric cancer cells: in vitro and in vivo studies.
    Lei CS, Hou YC, Pai MH, Lin MT, Yeh SL.
    J Nutr Biochem; 2018 Jan 02; 51():105-113. PubMed ID: 29125991
    [Abstract] [Full Text] [Related]

  • 19. Combined SN-38 and gefitinib treatment promotes CD44 degradation in head and neck squamous cell carcinoma cells.
    Nanbu T, Umemura N, Ohkoshi E, Nanbu K, Sakagami H, Shimada J.
    Oncol Rep; 2018 Jan 02; 39(1):367-375. PubMed ID: 29192320
    [Abstract] [Full Text] [Related]

  • 20. Hypoxia inducible factor 1α and hypoxia inducible factor 2α play distinct and functionally overlapping roles in oral squamous cell carcinoma.
    Zhu GQ, Tang YL, Li L, Zheng M, Jiang J, Li XY, Chen SX, Liang XH.
    Clin Cancer Res; 2010 Oct 01; 16(19):4732-41. PubMed ID: 20807755
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 7.