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348 related items for PubMed ID: 16518538

  • 1. Human acyl-CoA:cholesterol acyltransferase (ACAT) and its potential as a target for pharmaceutical intervention against atherosclerosis.
    Chang C, Dong R, Miyazaki A, Sakashita N, Zhang Y, Liu J, Guo M, Li BL, Chang TY.
    Acta Biochim Biophys Sin (Shanghai); 2006 Mar; 38(3):151-6. PubMed ID: 16518538
    [Abstract] [Full Text] [Related]

  • 2. Potential role of acyl-coenzyme A:cholesterol transferase (ACAT) Inhibitors as hypolipidemic and antiatherosclerosis drugs.
    Leon C, Hill JS, Wasan KM.
    Pharm Res; 2005 Oct; 22(10):1578-88. PubMed ID: 16180116
    [Abstract] [Full Text] [Related]

  • 3. Acyl-coenzyme A:cholesterol acyltransferase inhibitors for controlling hypercholesterolemia and atherosclerosis.
    Miyazaki A, Sakai M, Sakamoto Y, Horiuchi S.
    Curr Opin Investig Drugs; 2003 Sep; 4(9):1095-9. PubMed ID: 14582454
    [Abstract] [Full Text] [Related]

  • 4. Incorporation of lipoxygenase products into cholesteryl esters by acyl-CoA:cholesterol acyltransferase in cholesterol-rich macrophages.
    Mathur SN, Albright E, Field FJ.
    Biochem J; 1988 Dec 15; 256(3):807-14. PubMed ID: 3223954
    [Abstract] [Full Text] [Related]

  • 5. Acyl coenzyme A:cholesterol acyltransferase inhibitors as hypolipidemic and antiatherosclerotic drugs.
    Alegret M, Llaverias G, Silvestre JS.
    Methods Find Exp Clin Pharmacol; 2004 Sep 15; 26(7):563-86. PubMed ID: 15538545
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of acyl-CoA cholesterol acyltransferase by F12511 (Eflucimibe): could it be a new antiatherosclerotic therapeutic?
    López-Farré AJ, Sacristán D, Zamorano-León JJ, San-Martín N, Macaya C.
    Cardiovasc Ther; 2008 Sep 15; 26(1):65-74. PubMed ID: 18466422
    [Abstract] [Full Text] [Related]

  • 7. Impaired mobilisation of cholesterol from stored cholesteryl esters in human (THP-1) macrophages.
    Graham A, Angell AD, Jepson CA, Yeaman SJ, Hassall DG.
    Atherosclerosis; 1996 Feb 15; 120(1-2):135-45. PubMed ID: 8645354
    [Abstract] [Full Text] [Related]

  • 8. Inhibitors of acyl-coenzyme a: cholesterol acyltransferase.
    Miyazaki A, Kanome T, Watanabe T.
    Curr Drug Targets Cardiovasc Haematol Disord; 2005 Dec 15; 5(6):463-9. PubMed ID: 16503866
    [Abstract] [Full Text] [Related]

  • 9. Microsomal long chain fatty acyl-CoA transacylation: differential effect of sterol carrier protein-2.
    Chao H, Billheimer JT, Kier AB, Schroeder F.
    Biochim Biophys Acta; 1999 Aug 18; 1439(3):371-83. PubMed ID: 10498408
    [Abstract] [Full Text] [Related]

  • 10. 12-[(5-iodo-4-azido-2-hydroxybenzoyl)amino]dodecanoic acid: biological recognition by cholesterol esterase and acyl-CoA:cholesterol O-acyltransferase.
    Kinnunen PM, Klopf FH, Bastiani CA, Gelfman CM, Lange LG.
    Biochemistry; 1990 Feb 13; 29(6):1648-54. PubMed ID: 2334723
    [Abstract] [Full Text] [Related]

  • 11. Chemical modification of acyl-CoA:cholesterol O-acyltransferase. 2. Identification of a coenzyme A regulatory site by p-mercuribenzoate modification.
    Kinnunen PM, Spilburg CA, Lange LG.
    Biochemistry; 1988 Sep 20; 27(19):7351-6. PubMed ID: 3207681
    [Abstract] [Full Text] [Related]

  • 12. Role of acyl-coenzyme a: cholesterol acyltransferase activity in the processing of the amyloid precursor protein.
    Puglielli L, Ellis BC, Ingano LA, Kovacs DM.
    J Mol Neurosci; 2004 Sep 20; 24(1):93-6. PubMed ID: 15314256
    [Abstract] [Full Text] [Related]

  • 13. Acyl coenzyme A:cholesterol acyltransferase inhibition: potential atherosclerosis therapy or springboard for other discoveries?
    Heinonen TM.
    Expert Opin Investig Drugs; 2002 Nov 20; 11(11):1519-27. PubMed ID: 12437499
    [Abstract] [Full Text] [Related]

  • 14.
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  • 15. Demonstration of a direct effect on hepatic acyl CoA: cholesterol acyl transferase (ACAT) activity by an orally administered enzyme inhibitor in the hamster.
    Burrier RE, Deren S, McGregor DG, Hoos LM, Smith AA, Davis HR.
    Biochem Pharmacol; 1994 Apr 29; 47(9):1545-51. PubMed ID: 8185666
    [Abstract] [Full Text] [Related]

  • 16. Regulation of ovarian cholesterol metabolism: control of 3-hydroxy-3-methylglutaryl coenzyme A reductase and acyl coenzyme A:cholesterol acyltransferase.
    Schuler LA, Toaff ME, Strauss JF.
    Endocrinology; 1981 Apr 29; 108(4):1476-86. PubMed ID: 7472277
    [Abstract] [Full Text] [Related]

  • 17. Acyl coenzyme A: cholesterol acyltransferase inhibition and hepatic apolipoprotein B secretion.
    Burnett JR, Wilcox LJ, Huff MW.
    Clin Chim Acta; 1999 Aug 29; 286(1-2):231-42. PubMed ID: 10511295
    [Abstract] [Full Text] [Related]

  • 18. Preferential pharmacological inhibition of macrophage ACAT increases plaque formation in mouse and rabbit models of atherogenesis.
    Perrey S, Legendre C, Matsuura A, Guffroy C, Binet J, Ohbayashi S, Tanaka T, Ortuno JC, Matsukura T, Laugel T, Padovani P, Bellamy F, Edgar AD.
    Atherosclerosis; 2001 Apr 29; 155(2):359-70. PubMed ID: 11254906
    [Abstract] [Full Text] [Related]

  • 19. Acyl-CoA:cholesterol acyltransferase inhibition reduces atherosclerosis in apolipoprotein E-deficient mice.
    Kusunoki J, Hansoty DK, Aragane K, Fallon JT, Badimon JJ, Fisher EA.
    Circulation; 2001 May 29; 103(21):2604-9. PubMed ID: 11382731
    [Abstract] [Full Text] [Related]

  • 20. Pharmacological properties of R-755, a novel acyl-CoA:cholesterol acyltransferase inhibitor, in cholesterol-fed rats, hamsters and rabbits.
    Matsui Y, Horiuchi K, Yamamoto K, Kanai K.
    Jpn J Pharmacol; 2001 Apr 29; 85(4):423-33. PubMed ID: 11388647
    [Abstract] [Full Text] [Related]

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