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448 related items for PubMed ID: 16530734

  • 21. Repression of malignant tumor progression upon pharmacologic IGF1R blockade in a mouse model of insulinoma.
    Zumsteg A, Caviezel C, Pisarsky L, Strittmatter K, García-Echeverría C, Hofmann F, Christofori G.
    Mol Cancer Res; 2012 Jun; 10(6):800-9. PubMed ID: 22562956
    [Abstract] [Full Text] [Related]

  • 22. Effects of insulin-like growth factor-1 receptor inhibition in mesothelioma. Thoracic Surgery Directors Association Resident Research Award.
    Whitson BA, Jacobson BA, Frizelle S, Patel MR, Yee D, Maddaus MA, Kratzke RA.
    Ann Thorac Surg; 2006 Sep; 82(3):996-1001; discussion 1001-2. PubMed ID: 16928523
    [Abstract] [Full Text] [Related]

  • 23. Co-Targeting IGF-1R and Autophagy Enhances the Effects of Cell Growth Suppression and Apoptosis Induced by the IGF-1R Inhibitor NVP-AEW541 in Triple-Negative Breast Cancer Cells.
    Wu W, Ma J, Shao N, Shi Y, Liu R, Li W, Lin Y, Wang S.
    PLoS One; 2017 Sep; 12(1):e0169229. PubMed ID: 28046018
    [Abstract] [Full Text] [Related]

  • 24. Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas.
    Piao W, Wang Y, Adachi Y, Yamamoto H, Li R, Imsumran A, Li H, Maehata T, Ii M, Arimura Y, Lee CT, Shinomura Y, Carbone DP, Imai K.
    Mol Cancer Ther; 2008 Jun; 7(6):1483-93. PubMed ID: 18566219
    [Abstract] [Full Text] [Related]

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  • 26. Insulin-like growth factor-type 1 receptor inhibitor NVP-AEW541 enhances radiosensitivity of PTEN wild-type but not PTEN-deficient human prostate cancer cells.
    Isebaert SF, Swinnen JV, McBride WH, Haustermans KM.
    Int J Radiat Oncol Biol Phys; 2011 Sep 01; 81(1):239-47. PubMed ID: 21816290
    [Abstract] [Full Text] [Related]

  • 27. The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy.
    Warshamana-Greene GS, Litz J, Buchdunger E, García-Echeverría C, Hofmann F, Krystal GW.
    Clin Cancer Res; 2005 Feb 15; 11(4):1563-71. PubMed ID: 15746061
    [Abstract] [Full Text] [Related]

  • 28. Treatment of biliary tract cancer with NVP-AEW541: mechanisms of action and resistance.
    Wolf S, Lorenz J, Mössner J, Wiedmann M.
    World J Gastroenterol; 2010 Jan 14; 16(2):156-66. PubMed ID: 20066734
    [Abstract] [Full Text] [Related]

  • 29. MicroRNA-122 confers sorafenib resistance to hepatocellular carcinoma cells by targeting IGF-1R to regulate RAS/RAF/ERK signaling pathways.
    Xu Y, Huang J, Ma L, Shan J, Shen J, Yang Z, Liu L, Luo Y, Yao C, Qian C.
    Cancer Lett; 2016 Feb 28; 371(2):171-81. PubMed ID: 26655273
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  • 31. Vertical blockade of the IGFR- PI3K/Akt/mTOR pathway for the treatment of hepatocellular carcinoma: the role of survivin.
    Ou DL, Lee BS, Lin LI, Liou JY, Liao SC, Hsu C, Cheng AL.
    Mol Cancer; 2014 Jan 03; 13():2. PubMed ID: 24387108
    [Abstract] [Full Text] [Related]

  • 32. Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells.
    Strömberg T, Feng X, Delforoush M, Berglund M, Lin Y, Axelson M, Larsson O, Georgii-Hemming P, Lennartsson J, Enblad G.
    Med Oncol; 2015 Jul 03; 32(7):188. PubMed ID: 26021470
    [Abstract] [Full Text] [Related]

  • 33. Protein kinase B modulates the sensitivity of human neuroblastoma cells to insulin-like growth factor receptor inhibition.
    Guerreiro AS, Boller D, Shalaby T, Grotzer MA, Arcaro A.
    Int J Cancer; 2006 Dec 01; 119(11):2527-38. PubMed ID: 16988940
    [Abstract] [Full Text] [Related]

  • 34. Specific targeting of insulin-like growth factor 1 receptor signaling in human estrogen dependent breast cancer cell by a novel tyrosine-based benzoxazepine derivative.
    Chakravarti B, Siddiqui JA, Dwivedi SK, Deshpande S, Samanta K, Bhatta RS, Panda G, Prabhakar YS, Konwar R, Sanyal S, Chattopadhyay N.
    Mol Cell Endocrinol; 2011 May 16; 338(1-2):68-78. PubMed ID: 21457754
    [Abstract] [Full Text] [Related]

  • 35. Blockade of IGF-IR exerts anticancer effects in hepatocellular carcinoma.
    Yao WF, Liu JW, Sheng GL, Huang DS.
    Mol Med Rep; 2011 May 16; 4(4):719-22. PubMed ID: 21567089
    [Abstract] [Full Text] [Related]

  • 36. Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics.
    Huether A, Höpfner M, Sutter AP, Schuppan D, Scherübl H.
    J Hepatol; 2005 Oct 16; 43(4):661-9. PubMed ID: 16023762
    [Abstract] [Full Text] [Related]

  • 37. Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.
    Pennarun B, Kleibeuker JH, Oenema T, Stegehuis JH, de Vries EG, de Jong S.
    Anal Cell Pathol (Amst); 2010 Oct 16; 33(5):229-44. PubMed ID: 20978316
    [Abstract] [Full Text] [Related]

  • 38. Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL.
    Pennarun B, Kleibeuker JH, Oenema T, Stegehuis JH, de Vries EG, de Jong S.
    Cell Oncol (Dordr); 2011 Jun 16; 34(3):245-59. PubMed ID: 21538027
    [Abstract] [Full Text] [Related]

  • 39. Mechanisms of acquired resistance to insulin-like growth factor 1 receptor inhibitor in MCF-7 breast cancer cell line.
    Ekyalongo RC, Mukohara T, Kataoka Y, Funakoshi Y, Tomioka H, Kiyota N, Fujiwara Y, Minami H.
    Invest New Drugs; 2013 Apr 16; 31(2):293-303. PubMed ID: 22828916
    [Abstract] [Full Text] [Related]

  • 40. EGFR blockade by cetuximab alone or as combination therapy for growth control of hepatocellular cancer.
    Huether A, Höpfner M, Baradari V, Schuppan D, Scherübl H.
    Biochem Pharmacol; 2005 Nov 25; 70(11):1568-78. PubMed ID: 16226226
    [Abstract] [Full Text] [Related]

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