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Journal Abstract Search

179 related items for PubMed ID: 16539377

  • 1. Synthesis and biological activity of 7-phenyl-6,9-dihydro-3H-pyrrolo[3,2-f]quinolin-9-ones: a new class of antimitotic agents devoid of aromatase activity.
    Gasparotto V, Castagliuolo I, Chiarelotto G, Pezzi V, Montanaro D, Brun P, Palù G, Viola G, Ferlin MG.
    J Med Chem; 2006 Mar 23; 49(6):1910-5. PubMed ID: 16539377
    [Abstract] [Full Text] [Related]

  • 2. 3-substituted 7-phenyl-pyrroloquinolinones show potent cytotoxic activity in human cancer cell lines.
    Gasparotto V, Castagliuolo I, Ferlin MG.
    J Med Chem; 2007 Nov 01; 50(22):5509-13. PubMed ID: 17915851
    [Abstract] [Full Text] [Related]

  • 3. Pyrimido[4,5-c]quinolin-1(2H)-ones as a novel class of antimitotic agents: Synthesis and in vitro cytotoxic activity.
    Metwally K, Pratsinis H, Kletsas D.
    Eur J Med Chem; 2007 Mar 01; 42(3):344-50. PubMed ID: 17141923
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
    Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Balzarini J, Hadfield JA, Brancale A, Hamel E.
    J Med Chem; 2007 May 03; 50(9):2273-7. PubMed ID: 17419607
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
    Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Hsieh HP, Hamel E.
    J Med Chem; 2008 Mar 13; 51(5):1464-8. PubMed ID: 18260616
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, modelling, and antimitotic properties of tricyclic systems characterised by a 2-(5-Phenyl-1H-pyrrol-3-yl)-1,3,4-oxadiazole moiety.
    Pinna GA, Murineddu G, Murruzzu C, Zuco V, Zunino F, Cappelletti G, Artali R, Cignarella G, Solano L, Villa S.
    ChemMedChem; 2009 Jun 13; 4(6):998-1009. PubMed ID: 19291736
    [Abstract] [Full Text] [Related]

  • 7. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
    Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC.
    Bioorg Med Chem Lett; 2006 Mar 01; 16(5):1191-6. PubMed ID: 16377187
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and structure-activity relationships of carbazole sulfonamides as a novel class of antimitotic agents against solid tumors.
    Hu L, Li ZR, Li Y, Qu J, Ling YH, Jiang JD, Boykin DW.
    J Med Chem; 2006 Oct 19; 49(21):6273-82. PubMed ID: 17034133
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and in vitro and in vivo antitumor activity of 2-phenylpyrroloquinolin-4-ones.
    Ferlin MG, Chiarelotto G, Gasparotto V, Dalla Via L, Pezzi V, Barzon L, Palù G, Castagliuolo I.
    J Med Chem; 2005 May 05; 48(9):3417-27. PubMed ID: 15857148
    [Abstract] [Full Text] [Related]

  • 10. Benzoylurea derivatives as a novel class of antimitotic agents: synthesis, anticancer activity, and structure-activity relationships.
    Song DQ, Wang Y, Wu LZ, Yang P, Wang YM, Gao LM, Li Y, Qu JR, Wang YH, Li YH, Du NN, Han YX, Zhang ZP, Jiang JD.
    J Med Chem; 2008 Jun 12; 51(11):3094-103. PubMed ID: 18457382
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological evaluation of cinnamido linked pyrrolo[2,1-c][1,4]benzodiazepines as antimitotic agents.
    Kamal A, Balakishan G, Ramakrishna G, Shaik TB, Sreekanth K, Balakrishna M, Rajender, Dastagiri D, Kalivendi SV.
    Eur J Med Chem; 2010 Sep 12; 45(9):3870-84. PubMed ID: 20554354
    [Abstract] [Full Text] [Related]

  • 12. Antitumor Agents. 211. Fluorinated 2-phenyl-4-quinolone derivatives as antimitotic antitumor agents.
    Xia Y, Yang ZY, Xia P, Hackl T, Hamel E, Mauger A, Wu JH, Lee KH.
    J Med Chem; 2001 Nov 08; 44(23):3932-6. PubMed ID: 11689079
    [Abstract] [Full Text] [Related]

  • 13. Pyrrolo[3,4-h]quinolinones a new class of photochemotherapeutic agents.
    Barraja P, Diana P, Montalbano A, Carbone A, Viola G, Basso G, Salvador A, Vedaldi D, Dall'Acqua F, Cirrincione G.
    Bioorg Med Chem; 2011 Apr 01; 19(7):2326-41. PubMed ID: 21397509
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of novel pyrrolopyrrolizinones as anticancer agents.
    Rochais C, Lisowski V, Dallemagne P, Rault S.
    Bioorg Med Chem; 2006 Dec 15; 14(24):8162-75. PubMed ID: 17011196
    [Abstract] [Full Text] [Related]

  • 15. Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship.
    Boumendjel A, Boccard J, Carrupt PA, Nicolle E, Blanc M, Geze A, Choisnard L, Wouessidjewe D, Matera EL, Dumontet C.
    J Med Chem; 2008 Apr 10; 51(7):2307-10. PubMed ID: 18293907
    [Abstract] [Full Text] [Related]

  • 16. Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.
    Gallet S, Flouquet N, Carato P, Pfeiffer B, Renard P, Léonce S, Pierré A, Berthelot P, Lebegue N.
    Bioorg Med Chem; 2009 Feb 01; 17(3):1132-8. PubMed ID: 19162484
    [Abstract] [Full Text] [Related]

  • 17. Novel benzopyridothiadiazepines as potential active antitumor agents.
    Lebegue N, Gallet S, Flouquet N, Carato P, Pfeiffer B, Renard P, Léonce S, Pierré A, Chavatte P, Berthelot P.
    J Med Chem; 2005 Nov 17; 48(23):7363-73. PubMed ID: 16279796
    [Abstract] [Full Text] [Related]

  • 18. Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents.
    Liou JP, Mahindroo N, Chang CW, Guo FM, Lee SW, Tan UK, Yeh TK, Kuo CC, Chang YW, Lu PH, Tung YS, Lin KT, Chang JY, Hsieh HP.
    ChemMedChem; 2006 Oct 17; 1(10):1106-18. PubMed ID: 16952120
    [Abstract] [Full Text] [Related]

  • 19. Design, synthesis, and evaluation of novel thienopyrrolizinones as antitubulin agents.
    Lisowski V, Léonce S, Kraus-Berthier L, Sopková-de Oliveira Santos J, Pierré A, Atassi G, Caignard DH, Renard P, Rault S.
    J Med Chem; 2004 Mar 11; 47(6):1448-64. PubMed ID: 14998333
    [Abstract] [Full Text] [Related]

  • 20. Synthesis of a new 4-aza-2,3-didehydropodophyllotoxin analogues as potent cytotoxic and antimitotic agents.
    Kamal A, Suresh P, Mallareddy A, Kumar BA, Reddy PV, Raju P, Tamboli JR, Shaik TB, Jain N, Kalivendi SV.
    Bioorg Med Chem; 2011 Apr 01; 19(7):2349-58. PubMed ID: 21402478
    [Abstract] [Full Text] [Related]

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