These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

206 related items for PubMed ID: 1654318

  • 1. The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity.
    Liu LW, Vu TK, Esmon CT, Coughlin SR.
    J Biol Chem; 1991 Sep 15; 266(26):16977-80. PubMed ID: 1654318
    [Abstract] [Full Text] [Related]

  • 2. Allosteric changes in thrombin's activity produced by peptides corresponding to segments of natural inhibitors and substrates.
    Hortin GL, Trimpe BL.
    J Biol Chem; 1991 Apr 15; 266(11):6866-71. PubMed ID: 1849894
    [Abstract] [Full Text] [Related]

  • 3. The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity.
    Ye J, Liu LW, Esmon CT, Johnson AE.
    J Biol Chem; 1992 Jun 05; 267(16):11023-8. PubMed ID: 1317850
    [Abstract] [Full Text] [Related]

  • 4. Antithrombin activity of a peptide corresponding to residues 54-75 of heparin cofactor II.
    Hortin GL, Tollefsen DM, Benutto BM.
    J Biol Chem; 1989 Aug 25; 264(24):13979-82. PubMed ID: 2760054
    [Abstract] [Full Text] [Related]

  • 5. Domains specifying thrombin-receptor interaction.
    Vu TK, Wheaton VI, Hung DT, Charo I, Coughlin SR.
    Nature; 1991 Oct 17; 353(6345):674-7. PubMed ID: 1717851
    [Abstract] [Full Text] [Related]

  • 6. Hirudin: amino-terminal residues play a major role in the interaction with thrombin.
    Lazar JB, Winant RC, Johnson PH.
    J Biol Chem; 1991 Jan 15; 266(2):685-8. PubMed ID: 1985956
    [Abstract] [Full Text] [Related]

  • 7. Mapping of the thrombin des-ETW conformation by using site-directed mutants of hirudin. Evidence for the induction of nonlocal modifications by mutagenesis.
    Le Bonniec BF, Betz A, Guinto ER, Esmon CT, Stone SR.
    Biochemistry; 1994 Apr 05; 33(13):3959-66. PubMed ID: 8142400
    [Abstract] [Full Text] [Related]

  • 8. The active site of thrombin is altered upon binding to thrombomodulin. Two distinct structural changes are detected by fluorescence, but only one correlates with protein C activation.
    Ye J, Esmon NL, Esmon CT, Johnson AE.
    J Biol Chem; 1991 Dec 05; 266(34):23016-21. PubMed ID: 1660464
    [Abstract] [Full Text] [Related]

  • 9. Allosteric modulation of the activity of thrombin.
    Duffy EJ, Angliker H, Le Bonniec BF, Stone SR.
    Biochem J; 1997 Jan 15; 321 ( Pt 2)(Pt 2):361-5. PubMed ID: 9020867
    [Abstract] [Full Text] [Related]

  • 10. Synthesis of peptide p-nitroanilides mimicking fibrinogen- and hirudin-binding to thrombin. Design of slow reacting thrombin substrates.
    Rijkers DT, Hemker HC, Tesser GI.
    Int J Pept Protein Res; 1996 Aug 15; 48(2):182-93. PubMed ID: 8872537
    [Abstract] [Full Text] [Related]

  • 11. Proteolytic formation of either of the two prothrombin activation intermediates results in formation of a hirugen-binding site.
    Liu LW, Ye J, Johnson AE, Esmon CT.
    J Biol Chem; 1991 Dec 15; 266(35):23633-6. PubMed ID: 1748641
    [Abstract] [Full Text] [Related]

  • 12. Interaction of hirudin with thrombin: identification of a minimal binding domain of hirudin that inhibits clotting activity.
    Mao SJ, Yates MT, Owen TJ, Krstenansky JL.
    Biochemistry; 1988 Oct 18; 27(21):8170-3. PubMed ID: 3233202
    [Abstract] [Full Text] [Related]

  • 13. Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.
    Qiu X, Yin M, Padmanabhan KP, Krstenansky JL, Tulinsky A.
    J Biol Chem; 1993 Sep 25; 268(27):20318-26. PubMed ID: 8376390
    [Abstract] [Full Text] [Related]

  • 14. Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition.
    Grütter MG, Priestle JP, Rahuel J, Grossenbacher H, Bode W, Hofsteenge J, Stone SR.
    EMBO J; 1990 Aug 25; 9(8):2361-5. PubMed ID: 2369893
    [Abstract] [Full Text] [Related]

  • 15. The structural elements of hirudin which bind to the fibrinogen recognition site of thrombin are exclusively located within its acidic C-terminal tail.
    Chang JY, Ngai PK, Rink H, Dennis S, Schlaeppi JM.
    FEBS Lett; 1990 Feb 26; 261(2):287-90. PubMed ID: 2107100
    [Abstract] [Full Text] [Related]

  • 16. The structure of a complex of recombinant hirudin and human alpha-thrombin.
    Rydel TJ, Ravichandran KG, Tulinsky A, Bode W, Huber R, Roitsch C, Fenton JW.
    Science; 1990 Jul 20; 249(4966):277-80. PubMed ID: 2374926
    [Abstract] [Full Text] [Related]

  • 17. Incorporation of noncoded amino acids into the N-terminal domain 1-47 of hirudin yields a highly potent and selective thrombin inhibitor.
    De Filippis V, Russo I, Vindigni A, Di Cera E, Salmaso S, Fontana A.
    Protein Sci; 1999 Oct 20; 8(10):2213-7. PubMed ID: 10548068
    [Abstract] [Full Text] [Related]

  • 18. Binding of hirudin to meizothrombin.
    Fischer BE, Schlokat U, Himmelspach M, Dorner F.
    Protein Eng; 1998 Aug 20; 11(8):715-21. PubMed ID: 9749925
    [Abstract] [Full Text] [Related]

  • 19. Electrostatic steering and ionic tethering in the formation of thrombin-hirudin complexes: the role of the thrombin anion-binding exosite-I.
    Myles T, Le Bonniec BF, Betz A, Stone SR.
    Biochemistry; 2001 Apr 24; 40(16):4972-9. PubMed ID: 11305913
    [Abstract] [Full Text] [Related]

  • 20. A strong thrombin-inhibitory prourokinase derivative with sequence elements from hirudin and the human thrombin receptor.
    Wnendt S, Janocha E, Steffens GJ, Strassburger W.
    Protein Eng; 1997 Feb 24; 10(2):169-73. PubMed ID: 9089816
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 11.