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PUBMED FOR HANDHELDS

Journal Abstract Search

177 related items for PubMed ID: 16548522

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  • 3. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
    Bentahir M, Nyabi O, Verhamme J, Tolia A, Horré K, Wiltfang J, Esselmann H, De Strooper B.
    J Neurochem; 2006 Feb; 96(3):732-42. PubMed ID: 16405513
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  • 5. Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.
    Funamoto S, Morishima-Kawashima M, Tanimura Y, Hirotani N, Saido TC, Ihara Y.
    Biochemistry; 2004 Oct 26; 43(42):13532-40. PubMed ID: 15491160
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  • 6. PEN-2 enhances gamma-cleavage after presenilin heterodimer formation.
    Shiraishi H, Sai X, Wang HQ, Maeda Y, Kurono Y, Nishimura M, Yanagisawa K, Komano H.
    J Neurochem; 2004 Sep 26; 90(6):1402-13. PubMed ID: 15341524
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  • 7. Co-expressed presenilin 1 NTF and CTF form functional gamma-secretase complexes in cells devoid of full-length protein.
    Laudon H, Mathews PM, Karlström H, Bergman A, Farmery MR, Nixon RA, Winblad B, Gandy SE, Lendahl U, Lundkvist J, Näslund J.
    J Neurochem; 2004 Apr 26; 89(1):44-53. PubMed ID: 15030388
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  • 9. APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages.
    Lefranc-Jullien S, Sunyach C, Checler F.
    J Neurochem; 2006 May 26; 97(3):807-17. PubMed ID: 16524370
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  • 10. Presenilin-dependent gamma-secretase on plasma membrane and endosomes is functionally distinct.
    Fukumori A, Okochi M, Tagami S, Jiang J, Itoh N, Nakayama T, Yanagida K, Ishizuka-Katsura Y, Morihara T, Kamino K, Tanaka T, Kudo T, Tanii H, Ikuta A, Haass C, Takeda M.
    Biochemistry; 2006 Apr 18; 45(15):4907-14. PubMed ID: 16605258
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  • 13. gamma-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal gamma-secretase activity.
    Strömberg K, Hansson EM, Laudon H, Bergstedt S, Näslund J, Lundkvist J, Lendahl U.
    J Neurochem; 2005 Nov 18; 95(3):880-90. PubMed ID: 16135086
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  • 20. Conserved "PAL" sequence in presenilins is essential for gamma-secretase activity, but not required for formation or stabilization of gamma-secretase complexes.
    Wang J, Brunkan AL, Hecimovic S, Walker E, Goate A.
    Neurobiol Dis; 2004 Apr 18; 15(3):654-66. PubMed ID: 15056474
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