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516 related items for PubMed ID: 16551868

  • 21. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
    Takada Y, Kobayashi Y, Aggarwal BB.
    J Biol Chem; 2005 Apr 29; 280(17):17203-12. PubMed ID: 15710601
    [Abstract] [Full Text] [Related]

  • 22. Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes.
    Shukla S, Gupta S.
    Clin Cancer Res; 2004 May 01; 10(9):3169-78. PubMed ID: 15131058
    [Abstract] [Full Text] [Related]

  • 23. The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta.
    Yore MM, Liby KT, Honda T, Gribble GW, Sporn MB.
    Mol Cancer Ther; 2006 Dec 01; 5(12):3232-9. PubMed ID: 17148759
    [Abstract] [Full Text] [Related]

  • 24. Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression.
    Shishodia S, Aggarwal BB.
    Oncogene; 2006 Mar 09; 25(10):1463-73. PubMed ID: 16331273
    [Abstract] [Full Text] [Related]

  • 25. CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-kappaB and NF-kappaB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells.
    Deeb D, Gao X, Dulchavsky SA, Gautam SC.
    J Exp Ther Oncol; 2008 Mar 09; 7(1):31-9. PubMed ID: 18472640
    [Abstract] [Full Text] [Related]

  • 26. Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis.
    Takada Y, Khuri FR, Aggarwal BB.
    J Biol Chem; 2004 Jun 18; 279(25):26287-99. PubMed ID: 15090542
    [Abstract] [Full Text] [Related]

  • 27. Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling.
    Gao X, Deeb D, Jiang H, Liu Y, Dulchavsky SA, Gautam SC.
    J Neurooncol; 2007 Sep 18; 84(2):147-57. PubMed ID: 17361329
    [Abstract] [Full Text] [Related]

  • 28. Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor.
    Takada Y, Fang X, Jamaluddin MS, Boyd DD, Aggarwal BB.
    J Biol Chem; 2004 Sep 17; 279(38):39541-54. PubMed ID: 15252041
    [Abstract] [Full Text] [Related]

  • 29. Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.
    Takada Y, Murakami A, Aggarwal BB.
    Oncogene; 2005 Oct 20; 24(46):6957-69. PubMed ID: 16007145
    [Abstract] [Full Text] [Related]

  • 30. Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.
    Sethi G, Ahn KS, Aggarwal BB.
    Mol Cancer Res; 2008 Jun 20; 6(6):1059-70. PubMed ID: 18567808
    [Abstract] [Full Text] [Related]

  • 31. Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.
    Ahn KS, Sethi G, Krishnan K, Aggarwal BB.
    J Biol Chem; 2007 Jan 05; 282(1):809-20. PubMed ID: 17114179
    [Abstract] [Full Text] [Related]

  • 32. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
    Pandey MK, Sung B, Kunnumakkara AB, Sethi G, Chaturvedi MM, Aggarwal BB.
    Cancer Res; 2008 Jul 01; 68(13):5370-9. PubMed ID: 18593939
    [Abstract] [Full Text] [Related]

  • 33. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G, Ahn KS, Sung B, Aggarwal BB.
    Mol Cancer Ther; 2008 Jun 01; 7(6):1604-14. PubMed ID: 18566231
    [Abstract] [Full Text] [Related]

  • 34. Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products.
    Ahn KS, Sethi G, Aggarwal BB.
    Mol Pharmacol; 2007 Jan 01; 71(1):209-19. PubMed ID: 17028156
    [Abstract] [Full Text] [Related]

  • 35. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis.
    Kunnumakkara AB, Ichikawa H, Anand P, Mohankumar CJ, Hema PS, Nair MS, Aggarwal BB.
    Mol Cancer Ther; 2008 Oct 01; 7(10):3306-17. PubMed ID: 18852134
    [Abstract] [Full Text] [Related]

  • 36. Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.
    Deeb D, Gao X, Jiang H, Dulchavsky SA, Gautam SC.
    Prostate; 2009 Jun 01; 69(8):851-60. PubMed ID: 19189297
    [Abstract] [Full Text] [Related]

  • 37. Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue.
    Pandey MK, Sandur SK, Sung B, Sethi G, Kunnumakkara AB, Aggarwal BB.
    J Biol Chem; 2007 Jun 15; 282(24):17340-50. PubMed ID: 17439942
    [Abstract] [Full Text] [Related]

  • 38. Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis.
    Manna SK, Aggarwal RS, Sethi G, Aggarwal BB, Ramesh GT.
    Clin Cancer Res; 2007 Apr 01; 13(7):2290-7. PubMed ID: 17404114
    [Abstract] [Full Text] [Related]

  • 39. Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis.
    Shishodia S, Koul D, Aggarwal BB.
    J Immunol; 2004 Aug 01; 173(3):2011-22. PubMed ID: 15265936
    [Abstract] [Full Text] [Related]

  • 40. Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9.
    Takada Y, Aggarwal BB.
    J Biol Chem; 2004 Feb 06; 279(6):4750-9. PubMed ID: 14630924
    [Abstract] [Full Text] [Related]


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