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Journal Abstract Search

169 related items for PubMed ID: 16565168

  • 1. Differential modulation of Cav1.2 and Cav1.3-mediated glucose-stimulated insulin secretion by cAMP in INS-1 cells: distinct roles for exchange protein directly activated by cAMP 2 (Epac2) and protein kinase A.
    Liu G, Jacobo SM, Hilliard N, Hockerman GH.
    J Pharmacol Exp Ther; 2006 Jul; 318(1):152-60. PubMed ID: 16565168
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  • 3. Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM.
    Chepurny OG, Leech CA, Kelley GG, Dzhura I, Dzhura E, Li X, Rindler MJ, Schwede F, Genieser HG, Holz GG.
    J Biol Chem; 2009 Apr 17; 284(16):10728-36. PubMed ID: 19244230
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  • 5. PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.
    Chepurny OG, Kelley GG, Dzhura I, Leech CA, Roe MW, Dzhura E, Li X, Schwede F, Genieser HG, Holz GG.
    Am J Physiol Endocrinol Metab; 2010 Mar 17; 298(3):E622-33. PubMed ID: 20009023
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  • 7. Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans.
    Dzhura I, Chepurny OG, Leech CA, Roe MW, Dzhura E, Xu X, Lu Y, Schwede F, Genieser HG, Smrcka AV, Holz GG.
    Islets; 2011 Mar 17; 3(3):121-8. PubMed ID: 21478675
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  • 8. Uncoupling of Cav1.2 from Ca(2+)-induced Ca(2+) release and SK channel regulation in pancreatic β-cells.
    Wang Y, Jarrard RE, Pratt EP, Guerra ML, Salyer AE, Lange AM, Soderling IM, Hockerman GH.
    Mol Endocrinol; 2014 Apr 17; 28(4):458-76. PubMed ID: 24506535
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  • 10. cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.
    Kang G, Chepurny OG, Malester B, Rindler MJ, Rehmann H, Bos JL, Schwede F, Coetzee WA, Holz GG.
    J Physiol; 2006 Jun 15; 573(Pt 3):595-609. PubMed ID: 16613879
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  • 11. Triphenyltin impairs a protein kinase A (PKA)-dependent increase of cytosolic Na+ and Ca2+ and PKA-independent increase of cytosolic Ca2+ associated with insulin secretion in hamster pancreatic beta-cells.
    Miura Y, Matsui H.
    Toxicol Appl Pharmacol; 2006 Nov 01; 216(3):363-72. PubMed ID: 16837018
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  • 12. Restoration of Glucose-Stimulated Cdc42-Pak1 Activation and Insulin Secretion by a Selective Epac Activator in Type 2 Diabetic Human Islets.
    Veluthakal R, Chepurny OG, Leech CA, Schwede F, Holz GG, Thurmond DC.
    Diabetes; 2018 Oct 01; 67(10):1999-2011. PubMed ID: 29986926
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  • 14. Glucotoxicity inhibits cAMP-protein kinase A-potentiated glucose-stimulated insulin secretion in pancreatic β-cells.
    Kong X, Yan D, Wu X, Guan Y, Ma X.
    J Diabetes; 2015 May 01; 7(3):378-85. PubMed ID: 24981285
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  • 17. Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase A regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet beta cells.
    Kwan EP, Gao X, Leung YM, Gaisano HY.
    Pancreas; 2007 Oct 01; 35(3):e45-54. PubMed ID: 17895835
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  • 20. Calcium/calmodulin-dependent serine protein kinase is involved in exendin-4-induced insulin secretion in INS-1 cells.
    Zhu ZQ, Wang D, Xiang D, Yuan YX, Wang Y.
    Metabolism; 2014 Jan 01; 63(1):120-6. PubMed ID: 24140090
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