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460 related items for PubMed ID: 16565419

  • 1. Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation.
    Constante M, Jiang W, Wang D, Raymond VA, Bilodeau M, Santos MM.
    Am J Physiol Gastrointest Liver Physiol; 2006 Aug; 291(2):G229-37. PubMed ID: 16565419
    [Abstract] [Full Text] [Related]

  • 2. Repression of repulsive guidance molecule C during inflammation is independent of Hfe and involves tumor necrosis factor-alpha.
    Constante M, Wang D, Raymond VA, Bilodeau M, Santos MM.
    Am J Pathol; 2007 Feb; 170(2):497-504. PubMed ID: 17255318
    [Abstract] [Full Text] [Related]

  • 3. Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis.
    Ludwiczek S, Theurl I, Bahram S, Schümann K, Weiss G.
    J Cell Physiol; 2005 Aug; 204(2):489-99. PubMed ID: 15744772
    [Abstract] [Full Text] [Related]

  • 4. Contribution of Hfe expression in macrophages to the regulation of hepatic hepcidin levels and iron loading.
    Makui H, Soares RJ, Jiang W, Constante M, Santos MM.
    Blood; 2005 Sep 15; 106(6):2189-95. PubMed ID: 15914561
    [Abstract] [Full Text] [Related]

  • 5. Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin.
    Kent P, Wilkinson N, Constante M, Fillebeen C, Gkouvatsos K, Wagner J, Buffler M, Becker C, Schümann K, Santos MM, Pantopoulos K.
    J Mol Med (Berl); 2015 May 15; 93(5):489-98. PubMed ID: 25609138
    [Abstract] [Full Text] [Related]

  • 6. Effects of alcohol consumption on iron metabolism in mice with hemochromatosis mutations.
    Flanagan JM, Peng H, Beutler E.
    Alcohol Clin Exp Res; 2007 Jan 15; 31(1):138-43. PubMed ID: 17207112
    [Abstract] [Full Text] [Related]

  • 7. Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis.
    Muckenthaler M, Roy CN, Custodio AO, Miñana B, deGraaf J, Montross LK, Andrews NC, Hentze MW.
    Nat Genet; 2003 May 15; 34(1):102-7. PubMed ID: 12704390
    [Abstract] [Full Text] [Related]

  • 8. Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.
    Wallace DF, Summerville L, Crampton EM, Frazer DM, Anderson GJ, Subramaniam VN.
    Hepatology; 2009 Dec 15; 50(6):1992-2000. PubMed ID: 19824072
    [Abstract] [Full Text] [Related]

  • 9. Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin.
    Herrmann T, Muckenthaler M, van der Hoeven F, Brennan K, Gehrke SG, Hubert N, Sergi C, Gröne HJ, Kaiser I, Gosch I, Volkmann M, Riedel HD, Hentze MW, Stewart AF, Stremmel W.
    J Mol Med (Berl); 2004 Jan 15; 82(1):39-48. PubMed ID: 14618243
    [Abstract] [Full Text] [Related]

  • 10. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.
    Bridle KR, Frazer DM, Wilkins SJ, Dixon JL, Purdie DM, Crawford DH, Subramaniam VN, Powell LW, Anderson GJ, Ramm GA.
    Lancet; 2003 Feb 22; 361(9358):669-73. PubMed ID: 12606179
    [Abstract] [Full Text] [Related]

  • 11. Decreased liver hepcidin expression in the Hfe knockout mouse.
    Ahmad KA, Ahmann JR, Migas MC, Waheed A, Britton RS, Bacon BR, Sly WS, Fleming RE.
    Blood Cells Mol Dis; 2002 Feb 22; 29(3):361-6. PubMed ID: 12547226
    [Abstract] [Full Text] [Related]

  • 12. HJV and HFE Play Distinct Roles in Regulating Hepcidin.
    Wu Q, Wang H, An P, Tao Y, Deng J, Zhang Z, Shen Y, Chen C, Min J, Wang F.
    Antioxid Redox Signal; 2015 May 20; 22(15):1325-36. PubMed ID: 25608116
    [Abstract] [Full Text] [Related]

  • 13. Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice.
    Delima RD, Chua AC, Tirnitz-Parker JE, Gan EK, Croft KD, Graham RM, Olynyk JK, Trinder D.
    Hepatology; 2012 Aug 20; 56(2):585-93. PubMed ID: 22383097
    [Abstract] [Full Text] [Related]

  • 14. The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression.
    Schmidt PJ, Toran PT, Giannetti AM, Bjorkman PJ, Andrews NC.
    Cell Metab; 2008 Mar 20; 7(3):205-14. PubMed ID: 18316026
    [Abstract] [Full Text] [Related]

  • 15. Hepcidin expression does not rescue the iron-poor phenotype of Kupffer cells in Hfe-null mice after liver transplantation.
    Garuti C, Tian Y, Montosi G, Sabelli M, Corradini E, Graf R, Ventura P, Vegetti A, Clavien PA, Pietrangelo A.
    Gastroenterology; 2010 Jul 20; 139(1):315-22.e1. PubMed ID: 20338170
    [Abstract] [Full Text] [Related]

  • 16. Iron stores modulate hepatic hepcidin expression by an HFE-independent pathway.
    Gehrke SG, Herrmann T, Kulaksiz H, Merle U, Bents K, Kaiser I, Riedel HD, Stremmel W.
    Digestion; 2005 Jul 20; 72(1):25-32. PubMed ID: 16103673
    [Abstract] [Full Text] [Related]

  • 17. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice.
    Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, Vaulont S.
    Proc Natl Acad Sci U S A; 2001 Jul 17; 98(15):8780-5. PubMed ID: 11447267
    [Abstract] [Full Text] [Related]

  • 18. Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis.
    Ramos P, Guy E, Chen N, Proenca CC, Gardenghi S, Casu C, Follenzi A, Van Rooijen N, Grady RW, de Sousa M, Rivella S.
    Blood; 2011 Jan 27; 117(4):1379-89. PubMed ID: 21059897
    [Abstract] [Full Text] [Related]

  • 19. Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.
    Gao J, Chen J, Kramer M, Tsukamoto H, Zhang AS, Enns CA.
    Cell Metab; 2009 Mar 27; 9(3):217-27. PubMed ID: 19254567
    [Abstract] [Full Text] [Related]

  • 20. Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice.
    Gao J, Chen J, De Domenico I, Koeller DM, Harding CO, Fleming RE, Koeberl DD, Enns CA.
    Blood; 2010 Apr 22; 115(16):3374-81. PubMed ID: 20177050
    [Abstract] [Full Text] [Related]

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