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568 related items for PubMed ID: 16571599

  • 1. WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic beta-cells.
    Yamada T, Ishihara H, Tamura A, Takahashi R, Yamaguchi S, Takei D, Tokita A, Satake C, Tashiro F, Katagiri H, Aburatani H, Miyazaki J, Oka Y.
    Hum Mol Genet; 2006 May 15; 15(10):1600-9. PubMed ID: 16571599
    [Abstract] [Full Text] [Related]

  • 2. Expressional and functional studies of Wolframin, the gene function deficient in Wolfram syndrome, in mice and patient cells.
    Philbrook C, Fritz E, Weiher H.
    Exp Gerontol; 2005 May 15; 40(8-9):671-8. PubMed ID: 16087305
    [Abstract] [Full Text] [Related]

  • 3. Endoplasmic reticulum stress and N-glycosylation modulate expression of WFS1 protein.
    Yamaguchi S, Ishihara H, Tamura A, Yamada T, Takahashi R, Takei D, Katagiri H, Oka Y.
    Biochem Biophys Res Commun; 2004 Dec 03; 325(1):250-6. PubMed ID: 15522226
    [Abstract] [Full Text] [Related]

  • 4. Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic beta-cells.
    Hatanaka M, Tanabe K, Yanai A, Ohta Y, Kondo M, Akiyama M, Shinoda K, Oka Y, Tanizawa Y.
    Hum Mol Genet; 2011 Apr 01; 20(7):1274-84. PubMed ID: 21199859
    [Abstract] [Full Text] [Related]

  • 5. ATF4-mediated induction of 4E-BP1 contributes to pancreatic beta cell survival under endoplasmic reticulum stress.
    Yamaguchi S, Ishihara H, Yamada T, Tamura A, Usui M, Tominaga R, Munakata Y, Satake C, Katagiri H, Tashiro F, Aburatani H, Tsukiyama-Kohara K, Miyazaki J, Sonenberg N, Oka Y.
    Cell Metab; 2008 Mar 01; 7(3):269-76. PubMed ID: 18316032
    [Abstract] [Full Text] [Related]

  • 6. Endoplasmic reticulum stress induces Wfs1 gene expression in pancreatic beta-cells via transcriptional activation.
    Ueda K, Kawano J, Takeda K, Yujiri T, Tanabe K, Anno T, Akiyama M, Nozaki J, Yoshinaga T, Koizumi A, Shinoda K, Oka Y, Tanizawa Y.
    Eur J Endocrinol; 2005 Jul 01; 153(1):167-76. PubMed ID: 15994758
    [Abstract] [Full Text] [Related]

  • 7. Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells.
    Lai E, Bikopoulos G, Wheeler MB, Rozakis-Adcock M, Volchuk A.
    Am J Physiol Endocrinol Metab; 2008 Mar 01; 294(3):E540-50. PubMed ID: 18198352
    [Abstract] [Full Text] [Related]

  • 8. Protective role for nitric oxide during the endoplasmic reticulum stress response in pancreatic beta-cells.
    Kitiphongspattana K, Khan TA, Ishii-Schrade K, Roe MW, Philipson LH, Gaskins HR.
    Am J Physiol Endocrinol Metab; 2007 Jun 01; 292(6):E1543-54. PubMed ID: 17264231
    [Abstract] [Full Text] [Related]

  • 9. Reduced insulin signaling and endoplasmic reticulum stress act synergistically to deteriorate pancreatic beta cell function.
    Matsuda T, Kido Y, Uchida T, Kasuga M.
    Kobe J Med Sci; 2008 Jul 18; 54(2):E114-21. PubMed ID: 18772613
    [Abstract] [Full Text] [Related]

  • 10. Protection of pancreatic beta-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies.
    Tsunekawa S, Yamamoto N, Tsukamoto K, Itoh Y, Kaneko Y, Kimura T, Ariyoshi Y, Miura Y, Oiso Y, Niki I.
    J Endocrinol; 2007 Apr 18; 193(1):65-74. PubMed ID: 17400804
    [Abstract] [Full Text] [Related]

  • 11. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.
    J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis.
    Jiang CC, Chen LH, Gillespie S, Wang YF, Kiejda KA, Zhang XD, Hersey P.
    Cancer Res; 2007 Oct 15; 67(20):9750-61. PubMed ID: 17942905
    [Abstract] [Full Text] [Related]

  • 13. Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis.
    Riggs AC, Bernal-Mizrachi E, Ohsugi M, Wasson J, Fatrai S, Welling C, Murray J, Schmidt RE, Herrera PL, Permutt MA.
    Diabetologia; 2005 Nov 15; 48(11):2313-21. PubMed ID: 16215705
    [Abstract] [Full Text] [Related]

  • 14. WFS1 protein modulates the free Ca(2+) concentration in the endoplasmic reticulum.
    Takei D, Ishihara H, Yamaguchi S, Yamada T, Tamura A, Katagiri H, Maruyama Y, Oka Y.
    FEBS Lett; 2006 Oct 16; 580(24):5635-40. PubMed ID: 16989814
    [Abstract] [Full Text] [Related]

  • 15. A lipidomic screen of palmitate-treated MIN6 β-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking.
    Boslem E, MacIntosh G, Preston AM, Bartley C, Busch AK, Fuller M, Laybutt DR, Meikle PJ, Biden TJ.
    Biochem J; 2011 Apr 01; 435(1):267-76. PubMed ID: 21265737
    [Abstract] [Full Text] [Related]

  • 16. ERp46 is reduced by high glucose and regulates insulin content in pancreatic beta-cells.
    Alberti A, Karamessinis P, Peroulis M, Kypreou K, Kavvadas P, Pagakis S, Politis PK, Charonis A.
    Am J Physiol Endocrinol Metab; 2009 Sep 01; 297(3):E812-21. PubMed ID: 19622788
    [Abstract] [Full Text] [Related]

  • 17. ER stress induces the expression of Jpk, which inhibits cell cycle progression in F9 teratocarcinoma cell.
    Kim HS, Kong KA, Chung H, Park S, Kim MH.
    Ann N Y Acad Sci; 2007 Jan 01; 1095():76-81. PubMed ID: 17404020
    [Abstract] [Full Text] [Related]

  • 18. The cell cycle inhibitory protein p21cip is not essential for maintaining beta-cell cycle arrest or beta-cell function in vivo.
    Cozar-Castellano I, Haught M, Stewart AF.
    Diabetes; 2006 Dec 01; 55(12):3271-8. PubMed ID: 17130470
    [Abstract] [Full Text] [Related]

  • 19. Modulation of palmitate-induced endoplasmic reticulum stress and apoptosis in pancreatic β-cells by stearoyl-CoA desaturase and Elovl6.
    Green CD, Olson LK.
    Am J Physiol Endocrinol Metab; 2011 Apr 01; 300(4):E640-9. PubMed ID: 21266672
    [Abstract] [Full Text] [Related]

  • 20. High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes.
    Huang CJ, Lin CY, Haataja L, Gurlo T, Butler AE, Rizza RA, Butler PC.
    Diabetes; 2007 Aug 01; 56(8):2016-27. PubMed ID: 17475933
    [Abstract] [Full Text] [Related]


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