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209 related items for PubMed ID: 16574986

  • 1. FTY720 suppresses CD4+CD44highCD62L- effector memory T cell-mediated colitis.
    Fujii R, Kanai T, Nemoto Y, Makita S, Oshima S, Okamoto R, Tsuchiya K, Totsuka T, Watanabe M.
    Am J Physiol Gastrointest Liver Physiol; 2006 Aug; 291(2):G267-74. PubMed ID: 16574986
    [Abstract] [Full Text] [Related]

  • 2. FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow.
    Fujii T, Tomita T, Kanai T, Nemoto Y, Totsuka T, Sakamoto N, Nakamura T, Tsuchiya K, Okamoto R, Watanabe M.
    Eur J Immunol; 2008 Dec; 38(12):3290-303. PubMed ID: 19009523
    [Abstract] [Full Text] [Related]

  • 3. The S1P receptor modulator FTY720 prevents the development of experimental colitis in mice.
    Deguchi Y, Andoh A, Yagi Y, Bamba S, Inatomi O, Tsujikawa T, Fujiyama Y.
    Oncol Rep; 2006 Oct; 16(4):699-703. PubMed ID: 16969482
    [Abstract] [Full Text] [Related]

  • 4. Immunosenescent colitogenic CD4(+) T cells convert to regulatory cells and suppress colitis.
    Totsuka T, Kanai T, Nemoto Y, Tomita T, Tsuchiya K, Sakamoto N, Okamoto R, Watanabe M.
    Eur J Immunol; 2008 May; 38(5):1275-86. PubMed ID: 18412161
    [Abstract] [Full Text] [Related]

  • 5. Bone marrow retaining colitogenic CD4+ T cells may be a pathogenic reservoir for chronic colitis.
    Nemoto Y, Kanai T, Makita S, Okamoto R, Totsuka T, Takeda K, Watanabe M.
    Gastroenterology; 2007 Jan; 132(1):176-89. PubMed ID: 17241870
    [Abstract] [Full Text] [Related]

  • 6. Th17 central memory T cells are reduced by FTY720 in patients with multiple sclerosis.
    Mehling M, Lindberg R, Raulf F, Kuhle J, Hess C, Kappos L, Brinkmann V.
    Neurology; 2010 Aug 03; 75(5):403-10. PubMed ID: 20592255
    [Abstract] [Full Text] [Related]

  • 7. Colitis-inducing potency of CD4+ T cells in immunodeficient, adoptive hosts depends on their state of activation, IL-12 responsiveness, and CD45RB surface phenotype.
    Claesson MH, Bregenholt S, Bonhagen K, Thoma S, Möller P, Grusby MJ, Leithäuser F, Nissen MH, Reimann J.
    J Immunol; 1999 Mar 15; 162(6):3702-10. PubMed ID: 10092833
    [Abstract] [Full Text] [Related]

  • 8. Naturally arising CD4+CD25+ regulatory T cells suppress the expansion of colitogenic CD4+CD44highCD62L- effector memory T cells.
    Kanai T, Tanimoto K, Nemoto Y, Fujii R, Makita S, Totsuka T, Watanabe M.
    Am J Physiol Gastrointest Liver Physiol; 2006 May 15; 290(5):G1051-8. PubMed ID: 16373426
    [Abstract] [Full Text] [Related]

  • 9. FTY720 preferentially depletes naive T cells from peripheral and lymphoid organs.
    Hofmann M, Brinkmann V, Zerwes HG.
    Int Immunopharmacol; 2006 Dec 20; 6(13-14):1902-10. PubMed ID: 17161343
    [Abstract] [Full Text] [Related]

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  • 12. Modulation of T cell homeostasis and alloreactivity under continuous FTY720 exposure.
    Metzler B, Gfeller P, Wieczorek G, Li J, Nuesslein-Hildesheim B, Katopodis A, Mueller M, Brinkmann V.
    Int Immunol; 2008 May 20; 20(5):633-44. PubMed ID: 18343890
    [Abstract] [Full Text] [Related]

  • 13. FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions.
    Daniel C, Sartory NA, Zahn N, Schmidt R, Geisslinger G, Radeke HH, Stein JM.
    Mol Immunol; 2007 Jul 20; 44(13):3305-16. PubMed ID: 17475330
    [Abstract] [Full Text] [Related]

  • 14. Polyclonal expansion of adoptively transferred CD4+ alpha beta T cells in the colonic lamina propria of scid mice with colitis.
    Rudolphi A, Bonhagen K, Reimann J.
    Eur J Immunol; 1996 May 20; 26(5):1156-63. PubMed ID: 8647181
    [Abstract] [Full Text] [Related]

  • 15. [An additional role of FTY720 in chronic colitis].
    Fujii T, Watanabe M.
    Nihon Rinsho Meneki Gakkai Kaishi; 2009 Feb 20; 32(1):7-14. PubMed ID: 19252372
    [Abstract] [Full Text] [Related]

  • 16. FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis.
    Mehling M, Brinkmann V, Antel J, Bar-Or A, Goebels N, Vedrine C, Kristofic C, Kuhle J, Lindberg RL, Kappos L.
    Neurology; 2008 Oct 14; 71(16):1261-7. PubMed ID: 18852441
    [Abstract] [Full Text] [Related]

  • 17. Continuous generation of colitogenic CD4(+) T cells in persistent colitis.
    Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Watanabe M.
    Eur J Immunol; 2008 May 14; 38(5):1264-74. PubMed ID: 18412157
    [Abstract] [Full Text] [Related]

  • 18. T cell-dependent protective effects of CpG motifs of bacterial DNA in experimental colitis are mediated by CD11c+ dendritic cells.
    Hofmann C, Dunger N, Grunwald N, Hämmerling GJ, Hoffmann P, Schölmerich J, Falk W, Obermeier F.
    Gut; 2010 Oct 14; 59(10):1347-54. PubMed ID: 20732920
    [Abstract] [Full Text] [Related]

  • 19. Blockade of NKG2D signaling prevents the development of murine CD4+ T cell-mediated colitis.
    Ito Y, Kanai T, Totsuka T, Okamoto R, Tsuchiya K, Nemoto Y, Yoshioka A, Tomita T, Nagaishi T, Sakamoto N, Sakanishi T, Okumura K, Yagita H, Watanabe M.
    Am J Physiol Gastrointest Liver Physiol; 2008 Jan 14; 294(1):G199-207. PubMed ID: 17962357
    [Abstract] [Full Text] [Related]

  • 20. Long-lived colitogenic CD4+ memory T cells residing outside the intestine participate in the perpetuation of chronic colitis.
    Nemoto Y, Kanai T, Kameyama K, Shinohara T, Sakamoto N, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sudo T, Matsumoto S, Watanabe M.
    J Immunol; 2009 Oct 15; 183(8):5059-68. PubMed ID: 19786550
    [Abstract] [Full Text] [Related]

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