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Journal Abstract Search

167 related items for PubMed ID: 1657912

  • 1. Effects of a novel lanosterol 14 alpha-demethylase inhibitor on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in Hep G2 cells.
    Mayer RJ, Adams JL, Bossard MJ, Berkhout TA.
    J Biol Chem; 1991 Oct 25; 266(30):20070-8. PubMed ID: 1657912
    [Abstract] [Full Text] [Related]

  • 2. Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in human hepatoma cell line Hep G2. Effects of inhibitors of cholesterol synthesis on enzyme activity.
    Boogaard A, Griffioen M, Cohen LH.
    Biochem J; 1987 Jan 15; 241(2):345-51. PubMed ID: 3036060
    [Abstract] [Full Text] [Related]

  • 3. Regulation of hepatic cholesterol biosynthesis. Effects of a cytochrome P-450 inhibitor on the formation and metabolism of oxygenated sterol products of lanosterol.
    Iglesias J, Gibbons GF.
    Biochem J; 1989 Dec 01; 264(2):495-502. PubMed ID: 2604729
    [Abstract] [Full Text] [Related]

  • 4. Lanosterol analogs: dual-action inhibitors of cholesterol biosynthesis.
    Frye LL, Leonard DA.
    Crit Rev Biochem Mol Biol; 1999 Dec 01; 34(2):123-40. PubMed ID: 10333389
    [Abstract] [Full Text] [Related]

  • 5. Oxolanosterol oximes: dual-action inhibitors of cholesterol biosynthesis.
    Frye LL, Cusack KP, Leonard DA, Anderson JA.
    J Lipid Res; 1994 Aug 01; 35(8):1333-44. PubMed ID: 7989858
    [Abstract] [Full Text] [Related]

  • 6. Effects of 19-oxygenated lanosterol derivatives on 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and lanosterol demethylase activity.
    Sonoda Y, Suzuki S, Udagawa K, Ota K, Tasaka R, Fukamachi Y, Sato Y.
    Biol Pharm Bull; 1996 Jan 01; 19(1):57-61. PubMed ID: 8820912
    [Abstract] [Full Text] [Related]

  • 7. Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase by 15 alpha-fluorolanost-7-en-3 beta-ol. A mechanism-based inhibitor of cholesterol biosynthesis.
    Trzaskos JM, Magolda RL, Favata MF, Fischer RT, Johnson PR, Chen HW, Ko SS, Leonard DA, Gaylor JL.
    J Biol Chem; 1993 Oct 25; 268(30):22591-9. PubMed ID: 7693673
    [Abstract] [Full Text] [Related]

  • 8. Modulation of regulatory oxysterol formation and low density lipoprotein suppression of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity by ketoconazole. A role for cytochrome P-450 in the regulation of HMG-CoA reductase in rat intestinal epithelial cells.
    Gupta A, Sexton RC, Rudney H.
    J Biol Chem; 1986 Jun 25; 261(18):8348-56. PubMed ID: 3722155
    [Abstract] [Full Text] [Related]

  • 9. The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Berkhout TA, Simon HM, Patel DD, Bentzen C, Niesor E, Jackson B, Suckling KE.
    J Biol Chem; 1996 Jun 14; 271(24):14376-82. PubMed ID: 8662919
    [Abstract] [Full Text] [Related]

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  • 11. Regulation of squalene synthetase in human hepatoma cell line Hep G2 by sterols, and not by mevalonate-derived non-sterols.
    Cohen LH, van Miert E, Griffioen M.
    Biochim Biophys Acta; 1989 Mar 14; 1002(1):69-73. PubMed ID: 2538145
    [Abstract] [Full Text] [Related]

  • 12. Posttranscriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in lens epithelial cells by mevalonate-derived nonsterols.
    Cenedella RJ.
    Exp Eye Res; 1997 Jul 14; 65(1):63-72. PubMed ID: 9237866
    [Abstract] [Full Text] [Related]

  • 13. 15-substituted lanosterols: post-transcriptional suppressors of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
    Anderson JA, Leonard DA, Cusack KP, Frye LL.
    Arch Biochem Biophys; 1995 Jan 10; 316(1):190-6. PubMed ID: 7840615
    [Abstract] [Full Text] [Related]

  • 14. Effect of a novel squalene epoxidase inhibitor, NB-598, on the regulation of cholesterol metabolism in Hep G2 cells.
    Hidaka Y, Hotta H, Nagata Y, Iwasawa Y, Horie M, Kamei T.
    J Biol Chem; 1991 Jul 15; 266(20):13171-7. PubMed ID: 1649182
    [Abstract] [Full Text] [Related]

  • 15. Azalanstat (RS-21607), a lanosterol 14 alpha-demethylase inhibitor with cholesterol-lowering activity.
    Burton PM, Swinney DC, Heller R, Dunlap B, Chiou M, Malonzo E, Haller J, Walker KA, Salari A, Murakami S.
    Biochem Pharmacol; 1995 Aug 08; 50(4):529-44. PubMed ID: 7646560
    [Abstract] [Full Text] [Related]

  • 16. In situ accumulation of 3 beta-hydroxylanost-8-en-32-aldehyde in hepatocyte cultures. A putative regulator of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity.
    Trzaskos JM, Favata MF, Fischer RT, Stam SH.
    J Biol Chem; 1987 Sep 05; 262(25):12261-8. PubMed ID: 3624256
    [Abstract] [Full Text] [Related]

  • 17. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by 3 beta-hydroxy-lanost-8-en-32-al, an intermediate in the conversion of lanosterol to cholesterol.
    Leonard DA, Kotarski MA, Tessiatore JE, Favata MF, Trzaskos JM.
    Arch Biochem Biophys; 1994 Apr 05; 310(1):152-7. PubMed ID: 8161198
    [Abstract] [Full Text] [Related]

  • 18. Pravastatin inhibited the cholesterol synthesis in human hepatoma cell line Hep G2 less than simvastatin and lovastatin, which is reflected in the upregulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and squalene synthase.
    Cohen LH, van Vliet A, Roodenburg L, Jansen LM, Griffioen M.
    Biochem Pharmacol; 1993 Jun 09; 45(11):2203-8. PubMed ID: 8517861
    [Abstract] [Full Text] [Related]

  • 19. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ.
    J Biol Chem; 1993 May 25; 268(15):11230-8. PubMed ID: 8388388
    [Abstract] [Full Text] [Related]

  • 20. Effects of compactin, mevalonate and low-density lipoprotein on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and low-density-lipoprotein-receptor activity in the human hepatoma cell line Hep G2.
    Cohen LH, Griffioen M, Havekes L, Schouten D, van Hinsbergh V, Kempen HJ.
    Biochem J; 1984 Aug 15; 222(1):35-9. PubMed ID: 6089762
    [Abstract] [Full Text] [Related]

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