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Journal Abstract Search

658 related items for PubMed ID: 16581944

  • 1. Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms.
    Lee HK, Moon JK, Chang CH, Choi H, Park HW, Park BS, Lee HS, Hwang EC, Lee YD, Liu KH, Kim JH.
    Drug Metab Dispos; 2006 Jul; 34(7):1090-5. PubMed ID: 16581944
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4.
    Casabar RC, Wallace AD, Hodgson E, Rose RL.
    Drug Metab Dispos; 2006 Oct; 34(10):1779-85. PubMed ID: 16855053
    [Abstract] [Full Text] [Related]

  • 3. CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
    Ramírez J, Innocenti F, Schuetz EG, Flockhart DA, Relling MV, Santucci R, Ratain MJ.
    Drug Metab Dispos; 2004 Sep; 32(9):930-6. PubMed ID: 15319333
    [Abstract] [Full Text] [Related]

  • 4. Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA.
    Jacobson PA, Green K, Birnbaum A, Remmel RP.
    Cancer Chemother Pharmacol; 2002 Jun; 49(6):461-7. PubMed ID: 12107550
    [Abstract] [Full Text] [Related]

  • 5. Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450.
    Ghosal A, Satoh H, Thomas PE, Bush E, Moore D.
    Drug Metab Dispos; 1996 Sep; 24(9):940-7. PubMed ID: 8886602
    [Abstract] [Full Text] [Related]

  • 6. Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450.
    Rehmel JL, Eckstein JA, Farid NA, Heim JB, Kasper SC, Kurihara A, Wrighton SA, Ring BJ.
    Drug Metab Dispos; 2006 Apr; 34(4):600-7. PubMed ID: 16415119
    [Abstract] [Full Text] [Related]

  • 7. Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes.
    Hijazi Y, Boulieu R.
    Drug Metab Dispos; 2002 Jul; 30(7):853-8. PubMed ID: 12065445
    [Abstract] [Full Text] [Related]

  • 8. Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin.
    Heyn H, White RB, Stevens JC.
    Drug Metab Dispos; 1996 Sep; 24(9):948-54. PubMed ID: 8886603
    [Abstract] [Full Text] [Related]

  • 9. Characterization of benidipine and its enantiomers' metabolism by human liver cytochrome P450 enzymes.
    Yoon YJ, Kim KB, Kim H, Seo KA, Kim HS, Cha IJ, Kim EY, Liu KH, Shin JG.
    Drug Metab Dispos; 2007 Sep; 35(9):1518-24. PubMed ID: 17537876
    [Abstract] [Full Text] [Related]

  • 10. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T, Shiraga T, Mitani Y, Terakawa M, Tokuma Y, Kagayama A.
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [Abstract] [Full Text] [Related]

  • 11. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite.
    Kazui M, Nishiya Y, Ishizuka T, Hagihara K, Farid NA, Okazaki O, Ikeda T, Kurihara A.
    Drug Metab Dispos; 2010 Jan; 38(1):92-9. PubMed ID: 19812348
    [Abstract] [Full Text] [Related]

  • 12. Potent inhibition of cytochrome P450 2B6 by sibutramine in human liver microsomes.
    Bae SH, Kwon MJ, Choi EJ, Zheng YF, Yoon KD, Liu KH, Bae SK.
    Chem Biol Interact; 2013 Sep 05; 205(1):11-9. PubMed ID: 23777987
    [Abstract] [Full Text] [Related]

  • 13. Investigation of the major human hepatic cytochrome P450 involved in 4-hydroxylation and N-dechloroethylation of trofosfamide.
    May-Manke A, Kroemer H, Hempel G, Bohnenstengel F, Hohenlöchter B, Blaschke G, Boos J.
    Cancer Chemother Pharmacol; 1999 Sep 05; 44(4):327-34. PubMed ID: 10447581
    [Abstract] [Full Text] [Related]

  • 14. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2001 Feb 05; 29(2):200-5. PubMed ID: 11159812
    [Abstract] [Full Text] [Related]

  • 15. Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies.
    Hamaoka N, Oda Y, Hase I, Asada A.
    Br J Anaesth; 2001 Apr 05; 86(4):540-4. PubMed ID: 11573629
    [Abstract] [Full Text] [Related]

  • 16. Measurement of in vitro cytochrome P450 2B6 activity.
    Walsky RL, Obach RS.
    Curr Protoc Toxicol; 2009 Apr 05; Chapter 4():Unit4.27. PubMed ID: 23045012
    [Abstract] [Full Text] [Related]

  • 17. Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes.
    Zhang WV, D'Esposito F, Edwards RJ, Ramzan I, Murray M.
    Drug Metab Dispos; 2008 Dec 05; 36(12):2547-55. PubMed ID: 18809730
    [Abstract] [Full Text] [Related]

  • 18. Oxidative metabolism of clarithromycin in the presence of human liver microsomes. Major role for the cytochrome P4503A (CYP3A) subfamily.
    Rodrigues AD, Roberts EM, Mulford DJ, Yao Y, Ouellet D.
    Drug Metab Dispos; 1997 May 05; 25(5):623-30. PubMed ID: 9152603
    [Abstract] [Full Text] [Related]

  • 19. Involvement of CYP3A in the metabolism of eplerenone in humans and dogs: differential metabolism by CYP3A4 and CYP3A5.
    Cook CS, Berry LM, Kim DH, Burton EG, Hribar JD, Zhang L.
    Drug Metab Dispos; 2002 Dec 05; 30(12):1344-51. PubMed ID: 12433801
    [Abstract] [Full Text] [Related]

  • 20. Indications for the involvement of a CYP3A-like iso-enzyme in the metabolism of chlorobornane (Toxaphene) congeners in seals from inhibition studies with liver microsomes.
    van Hezik CM, Letcher RJ, de Geus HJ, Wester PG, Goksøyr A, Lewis WE, Boon JP.
    Aquat Toxicol; 2001 Jan 05; 51(3):319-33. PubMed ID: 11090893
    [Abstract] [Full Text] [Related]

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