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147 related items for PubMed ID: 16596246

  • 1. Phenylhexyl isothiocyanate inhibits histone deacetylases and remodels chromatins to induce growth arrest in human leukemia cells.
    Ma X, Fang Y, Beklemisheva A, Dai W, Feng J, Ahmed T, Liu D, Chiao JW.
    Int J Oncol; 2006 May; 28(5):1287-93. PubMed ID: 16596246
    [Abstract] [Full Text] [Related]

  • 2. Epigenetic mechanism of growth inhibition induced by phenylhexyl isothiocyanate in prostate cancer cells.
    Beklemisheva AA, Fang Y, Feng J, Ma X, Dai W, Chiao JW.
    Anticancer Res; 2006 May; 26(2A):1225-30. PubMed ID: 16619528
    [Abstract] [Full Text] [Related]

  • 3. De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc.
    Wang LG, Liu XM, Fang Y, Dai W, Chiao FB, Puccio GM, Feng J, Liu D, Chiao JW.
    Int J Oncol; 2008 Aug; 33(2):375-80. PubMed ID: 18636159
    [Abstract] [Full Text] [Related]

  • 4. The phenylhexyl isothiocyanate induces apoptosis and inhibits leukemia cell growth in vivo.
    Lu L, Liu D, Ma X, Beklemishev A, Seiter K, Ahmed T, Chiao JW.
    Oncol Rep; 2006 Dec; 16(6):1363-7. PubMed ID: 17089062
    [Abstract] [Full Text] [Related]

  • 5. [Experiment study of PHI on histone methylation and acetylation in Molt-4 cells].
    Huang YQ, Ma XD, Zhen RJ, Chiao JW, Liu DL.
    Zhonghua Xue Ye Xue Za Zhi; 2007 Sep; 28(9):612-5. PubMed ID: 18246819
    [Abstract] [Full Text] [Related]

  • 6. Dual action on promoter demethylation and chromatin by an isothiocyanate restored GSTP1 silenced in prostate cancer.
    Wang LG, Beklemisheva A, Liu XM, Ferrari AC, Feng J, Chiao JW.
    Mol Carcinog; 2007 Jan; 46(1):24-31. PubMed ID: 16921492
    [Abstract] [Full Text] [Related]

  • 7. [Modulation of histone acetylation and induction of apoptosis in SMMC-7721 cells by phenylhexyl isothiocyanate].
    Lai YD, Ma XD, Huang YQ, Xu XN, Wang XZ, Chiao DJ, Liu D.
    Zhonghua Zhong Liu Za Zhi; 2010 Nov; 32(11):804-7. PubMed ID: 21223683
    [Abstract] [Full Text] [Related]

  • 8. [Phenylhexyl isothiocyanate (PHI) regulates histone methylation and acetylation and induces apoptosis in SMMC-7721 cells].
    Huang YQ, Ma XD, Lai YD, Wang XZ, Chiao JW, Liu DL.
    Zhonghua Gan Zang Bing Za Zhi; 2010 Mar; 18(3):209-12. PubMed ID: 20380799
    [Abstract] [Full Text] [Related]

  • 9. A natural histone deacetylase inhibitor, Psammaplin A, induces cell cycle arrest and apoptosis in human endometrial cancer cells.
    Ahn MY, Jung JH, Na YJ, Kim HS.
    Gynecol Oncol; 2008 Jan; 108(1):27-33. PubMed ID: 17920664
    [Abstract] [Full Text] [Related]

  • 10. Human ovarian carcinoma cells: histone deacetylase inhibitors exhibit antiproliferative activity and potently induce apoptosis.
    Takai N, Kawamata N, Gui D, Said JW, Miyakawa I, Koeffler HP.
    Cancer; 2004 Dec 15; 101(12):2760-70. PubMed ID: 15536623
    [Abstract] [Full Text] [Related]

  • 11. The novel histone deacetylase inhibitor BML-210 exerts growth inhibitory, proapoptotic and differentiation stimulating effects on the human leukemia cell lines.
    Savickiene J, Borutinskaite VV, Treigyte G, Magnusson KE, Navakauskiene R.
    Eur J Pharmacol; 2006 Nov 07; 549(1-3):9-18. PubMed ID: 16978604
    [Abstract] [Full Text] [Related]

  • 12. Cell cycle arrest and lytic induction of EBV-transformed B lymphoblastoid cells by a histone deacetylase inhibitor, Trichostatin A.
    Seo JS, Cho NY, Kim HR, Tsurumi T, Jang YS, Lee WK, Lee SK.
    Oncol Rep; 2008 Jan 07; 19(1):93-8. PubMed ID: 18097580
    [Abstract] [Full Text] [Related]

  • 13. YM753, a novel histone deacetylase inhibitor, exhibits antitumor activity with selective, sustained accumulation of acetylated histones in tumors in the WiDr xenograft model.
    Shindoh N, Mori M, Terada Y, Oda K, Amino N, Kita A, Taniguchi M, Sohda KY, Nagai K, Sowa Y, Masuoka Y, Orita M, Sasamata M, Matsushime H, Furuichi K, Sakai T.
    Int J Oncol; 2008 Mar 07; 32(3):545-55. PubMed ID: 18292931
    [Abstract] [Full Text] [Related]

  • 14. Histone deacetylase inhibitor-induced cellular apoptosis involves stanniocalcin-1 activation.
    Law AY, Lai KP, Lui WC, Wan HT, Wong CK.
    Exp Cell Res; 2008 Oct 01; 314(16):2975-84. PubMed ID: 18652825
    [Abstract] [Full Text] [Related]

  • 15. Deficient histone acetylation in acute leukemia and the correction by an isothiocyanate.
    Xiao L, Huang Y, Zhen R, Chiao JW, Liu D, Ma X.
    Acta Haematol; 2010 Oct 01; 123(2):71-6. PubMed ID: 20051681
    [Abstract] [Full Text] [Related]

  • 16. Romidepsin (depsipeptide) induced cell cycle arrest, apoptosis and histone hyperacetylation in lung carcinoma cells (A549) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression.
    Vinodhkumar R, Song YS, Devaki T.
    Biomed Pharmacother; 2008 Feb 01; 62(2):85-93. PubMed ID: 17644301
    [Abstract] [Full Text] [Related]

  • 17. Cu2+ is required for pyrrolidine dithiocarbamate to inhibit histone acetylation and induce human leukemia cell apoptosis.
    Chen J, Du C, Kang J, Wang J.
    Chem Biol Interact; 2008 Jan 10; 171(1):26-36. PubMed ID: 17961528
    [Abstract] [Full Text] [Related]

  • 18. [Effect of curcumin on acetylation of histone H3 in human lymphoma cell line Raji].
    Li XG, Chen Y, Wu Q, Sun CY.
    Ai Zheng; 2006 May 10; 25(5):582-6. PubMed ID: 16687078
    [Abstract] [Full Text] [Related]

  • 19. Response of retinoic acid-resistant KG1 cells to combination of retinoic acid with diverse histone deacetylase inhibitors.
    Savickiene J, Treigyte G, Magnusson KE, Navakauskiene R.
    Ann N Y Acad Sci; 2009 Aug 10; 1171():321-33. PubMed ID: 19723072
    [Abstract] [Full Text] [Related]

  • 20. Reactivating aberrantly hypermethylated p15 gene in leukemic T cells by a phenylhexyl isothiocyanate mediated inter-active mechanism on DNA and chromatin.
    Jiang S, Ma X, Huang Y, Xu Y, Zheng R, Chiao JW.
    J Hematol Oncol; 2010 Nov 29; 3():48. PubMed ID: 21114827
    [Abstract] [Full Text] [Related]


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