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239 related items for PubMed ID: 16599904

  • 1. Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.
    Ten Klooster JP, Evers EE, Janssen L, Machesky LM, Michiels F, Hordijk P, Collard JG.
    Biochem J; 2006 Jul 01; 397(1):39-45. PubMed ID: 16599904
    [Abstract] [Full Text] [Related]

  • 2. Rac is a dominant regulator of cadherin-directed actin assembly that is activated by adhesive ligation independently of Tiam1.
    Kraemer A, Goodwin M, Verma S, Yap AS, Ali RG.
    Am J Physiol Cell Physiol; 2007 Mar 01; 292(3):C1061-9. PubMed ID: 17020937
    [Abstract] [Full Text] [Related]

  • 3. Regulation of p70 S6 kinase by complex formation between the Rac guanine nucleotide exchange factor (Rac-GEF) Tiam1 and the scaffold spinophilin.
    Buchsbaum RJ, Connolly BA, Feig LA.
    J Biol Chem; 2003 May 23; 278(21):18833-41. PubMed ID: 12531897
    [Abstract] [Full Text] [Related]

  • 4. Tiam1-IRSp53 complex formation directs specificity of rac-mediated actin cytoskeleton regulation.
    Connolly BA, Rice J, Feig LA, Buchsbaum RJ.
    Mol Cell Biol; 2005 Jun 23; 25(11):4602-14. PubMed ID: 15899863
    [Abstract] [Full Text] [Related]

  • 5. The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites.
    Duman JG, Tzeng CP, Tu YK, Munjal T, Schwechter B, Ho TS, Tolias KF.
    J Neurosci; 2013 Apr 17; 33(16):6964-78. PubMed ID: 23595754
    [Abstract] [Full Text] [Related]

  • 6. Tiam1 and Rac1 are required for platelet-activating factor-induced endothelial junctional disassembly and increase in vascular permeability.
    Knezevic II, Predescu SA, Neamu RF, Gorovoy MS, Knezevic NM, Easington C, Malik AB, Predescu DN.
    J Biol Chem; 2009 Feb 20; 284(8):5381-94. PubMed ID: 19095647
    [Abstract] [Full Text] [Related]

  • 7. Dissociation of Rac1(GDP).RhoGDI complexes by the cooperative action of anionic liposomes containing phosphatidylinositol 3,4,5-trisphosphate, Rac guanine nucleotide exchange factor, and GTP.
    Ugolev Y, Berdichevsky Y, Weinbaum C, Pick E.
    J Biol Chem; 2008 Aug 08; 283(32):22257-71. PubMed ID: 18505730
    [Abstract] [Full Text] [Related]

  • 8. Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation.
    Michiels F, Stam JC, Hordijk PL, van der Kammen RA, Ruuls-Van Stalle L, Feltkamp CA, Collard JG.
    J Cell Biol; 1997 Apr 21; 137(2):387-98. PubMed ID: 9128250
    [Abstract] [Full Text] [Related]

  • 9. Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.
    Abou-Kheir W, Isaac B, Yamaguchi H, Cox D.
    J Cell Sci; 2008 Feb 01; 121(Pt 3):379-90. PubMed ID: 18198193
    [Abstract] [Full Text] [Related]

  • 10. Scaffold proteins IRSp53 and spinophilin regulate localized Rac activation by T-lymphocyte invasion and metastasis protein 1 (TIAM1).
    Rajagopal S, Ji Y, Xu K, Li Y, Wicks K, Liu J, Wong KW, Herman IM, Isberg RR, Buchsbaum RJ.
    J Biol Chem; 2010 Jun 04; 285(23):18060-71. PubMed ID: 20360004
    [Abstract] [Full Text] [Related]

  • 11. The Tiam1 guanine nucleotide exchange factor is auto-inhibited by its pleckstrin homology coiled-coil extension domain.
    Xu Z, Gakhar L, Bain FE, Spies M, Fuentes EJ.
    J Biol Chem; 2017 Oct 27; 292(43):17777-17793. PubMed ID: 28882897
    [Abstract] [Full Text] [Related]

  • 12. The guanine nucleotide exchange factor Tiam1: a Janus-faced molecule in cellular signaling.
    Boissier P, Huynh-Do U.
    Cell Signal; 2014 Mar 27; 26(3):483-91. PubMed ID: 24308970
    [Abstract] [Full Text] [Related]

  • 13. Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons.
    Čajánek L, Ganji RS, Henriques-Oliveira C, Theofilopoulos S, Koník P, Bryja V, Arenas E.
    Mol Cell Biol; 2013 Jan 27; 33(1):59-70. PubMed ID: 23109420
    [Abstract] [Full Text] [Related]

  • 14. Identification of another actin-related protein (Arp) 2/3 complex binding site in neural Wiskott-Aldrich syndrome protein (N-WASP) that complements actin polymerization induced by the Arp2/3 complex activating (VCA) domain of N-WASP.
    Suetsugu S, Miki H, Takenawa T.
    J Biol Chem; 2001 Aug 31; 276(35):33175-80. PubMed ID: 11432863
    [Abstract] [Full Text] [Related]

  • 15. Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration.
    Bourguignon LY, Zhu H, Shao L, Chen YW.
    J Cell Biol; 2000 Jul 10; 150(1):177-91. PubMed ID: 10893266
    [Abstract] [Full Text] [Related]

  • 16. The light chain 1 subunit of the microtubule-associated protein 1B (MAP1B) is responsible for Tiam1 binding and Rac1 activation in neuronal cells.
    Henríquez DR, Bodaleo FJ, Montenegro-Venegas C, González-Billault C.
    PLoS One; 2012 Jul 10; 7(12):e53123. PubMed ID: 23300879
    [Abstract] [Full Text] [Related]

  • 17. A SPIKE1 signaling complex controls actin-dependent cell morphogenesis through the heteromeric WAVE and ARP2/3 complexes.
    Basu D, Le J, Zakharova T, Mallery EL, Szymanski DB.
    Proc Natl Acad Sci U S A; 2008 Mar 11; 105(10):4044-9. PubMed ID: 18308939
    [Abstract] [Full Text] [Related]

  • 18. The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho.
    Leeuwen FN, Kain HE, Kammen RA, Michiels F, Kranenburg OW, Collard JG.
    J Cell Biol; 1997 Nov 03; 139(3):797-807. PubMed ID: 9348295
    [Abstract] [Full Text] [Related]

  • 19. The Rac-GAP Bcr is a novel regulator of the Par complex that controls cell polarity.
    Narayanan AS, Reyes SB, Um K, McCarty JH, Tolias KF.
    Mol Biol Cell; 2013 Dec 03; 24(24):3857-68. PubMed ID: 24152735
    [Abstract] [Full Text] [Related]

  • 20. Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1.
    Van Leeuwen FN, Olivo C, Grivell S, Giepmans BN, Collard JG, Moolenaar WH.
    J Biol Chem; 2003 Jan 03; 278(1):400-6. PubMed ID: 12393875
    [Abstract] [Full Text] [Related]

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