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Journal Abstract Search


422 related items for PubMed ID: 16600439

  • 1. Synthesis, anticonvulsant activity and 5-HT1A, 5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione.
    Obniska J, Kołaczkowski M, Bojarski AJ, Duszyńska B.
    Eur J Med Chem; 2006 Jul; 41(7):874-81. PubMed ID: 16600439
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and anticonvulsant properties of new N-phenylamino derivatives of 2-azaspiro[4.4]nonane, 2-azaspiro[4.5]decane-1,3-dione and 3-cyclohexylpyrrolidine-2,5-dione. Part IV.
    Obniska J, Kamiński K.
    Acta Pol Pharm; 2006 Jul; 63(2):101-8. PubMed ID: 17514872
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, physicochemical and anticonvulsant properties of new N-phenylamino derivatives of 2-azaspiro[4.4]nonane- and [4.5]decane-1,3-diones: part V.
    Kamiński K, Obniska J, Dybała M.
    Eur J Med Chem; 2008 Jan; 43(1):53-61. PubMed ID: 17475369
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, physicochemical and anticonvulsant properties of N-benzyl and N-aminophenyl derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione. Part I.
    Obniska J, Dzierzawska-Majewska A, Zagorska A, Zajdel P, Karolak-Wojciechowska J.
    Farmaco; 2005 Jan; 60(6-7):529-39. PubMed ID: 15950973
    [Abstract] [Full Text] [Related]

  • 5. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S, Kołaczkowski M, Maryniak E, Zajdel P, Pawłowski M, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E, Bojarski AJ, Charakchieva-Minol S, Duszyńska B, Nowak G, Maciag D.
    J Med Chem; 2004 May 06; 47(10):2659-66. PubMed ID: 15115407
    [Abstract] [Full Text] [Related]

  • 6. New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
    Fiorino F, Perissutti E, Severino B, Santagada V, Cirillo D, Terracciano S, Massarelli P, Bruni G, Collavoli E, Renner C, Caliendo G.
    J Med Chem; 2005 Aug 25; 48(17):5495-503. PubMed ID: 16107148
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, anticonvulsant properties and 5-HT1A/5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-propyl]-2-aza-spiro[4.4]nonane and [4.5]decane-1,3-dione derivatives.
    Obniska J, Kołaczkowski M, Charakchieva-Minol S, Nedza K, Dybała M, Bojarski AJ.
    Pharmacol Rep; 2005 Aug 25; 57(3):336-44. PubMed ID: 15985716
    [Abstract] [Full Text] [Related]

  • 8. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
    Bojarski AJ, Paluchowska MH, Duszyńska B, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2005 Mar 15; 13(6):2293-303. PubMed ID: 15727878
    [Abstract] [Full Text] [Related]

  • 9. New 4-[omega-(diarylmethylamino)alkyl]- and 4-[omega-(diarylmethoxy)alkyl]-1-arylpiperazines as selective 5-HT1A/5-HT2A receptor ligands with differentiated in vivo activity.
    Paluchowska MH, Charakchieva-Minol S, Tatarczyńska E, Kłodzińska A, Stachowicz K, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2004 Mar 15; 56(6):743-54. PubMed ID: 15662087
    [Abstract] [Full Text] [Related]

  • 10. The influence of an ethylene spacer on the 5-HT(1A) and 5-HT(2A) receptor affinity of arylpiperazine derivatives of amides with N-acylated amino acids and 3-differently substituted pyrrolidine-2,5-diones.
    Zajdel P, Subra G, Verdie P, Bojarski AJ, Duszyńska B, Basista K, Obniska J, Martinez J, Pawłowski M.
    Eur J Med Chem; 2009 Feb 15; 44(2):800-8. PubMed ID: 18603331
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, physicochemical and anticonvulsant properties of new N-[(4-arylpiperazin-1-yl)alkyl]-3-phenyl- and 3-(3-methyl-phenyl)-pyrrolidine-2,5-diones.
    Obniska J, Chlebek I, Pichór J, Kopytko M, Kamiński K.
    Acta Pol Pharm; 2009 Feb 15; 66(6):639-47. PubMed ID: 20050528
    [Abstract] [Full Text] [Related]

  • 12. Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation.
    Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Tatarczyńska E, Nikiforuk A, Chojnacka-Wójcik E, Pawłowski M, Martinez J.
    Bioorg Med Chem; 2007 Apr 15; 15(8):2907-19. PubMed ID: 17321139
    [Abstract] [Full Text] [Related]

  • 13. Synthesis and anticonvulsant properties of a series of N-substituted 2-aza-spiro[4.5]decane-1,3-diones and 8-phenyl-2-aza-spiro[4.5]decane-1,3-diones.
    Obniska J.
    Acta Pol Pharm; 2004 Apr 15; 61(6):467-72. PubMed ID: 15794340
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, physicochemical and anticonvulsant properties of new N-(pyridine-2-yl) derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione. Part II.
    Kaminski K, Obniska J, Zagorska A, Maciag D.
    Arch Pharm (Weinheim); 2006 May 15; 339(5):255-61. PubMed ID: 16511896
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and anticonvulsant activity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 3-phenyl-pyrrolidine-2,5-dione.
    Obniska J, Kaminski K, Skrzynska D, Pichor J.
    Eur J Med Chem; 2009 May 15; 44(5):2224-33. PubMed ID: 18603334
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and 5-HT1A/5-HT2A receptor activity of new N-[3-(4-phenylpiperazin-1-yl)-propyl] derivatives of 3-spiro-cyclohexanepyrrolidine-2,5-dione and 3-spiro-beta-tetralonepyrrolidine-2,5-dione.
    Obniska J, Pawłowski M, Kołaczkowski M, Czopek A, Duszyńska B, Klodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Pol J Pharmacol; 2003 May 15; 55(4):553-7. PubMed ID: 14581713
    [Abstract] [Full Text] [Related]

  • 17. Synthesis, anticonvulsant activity and 5-HT1A/5-HT7 receptors affinity of 1-[(4-arylpiperazin-1-yl)-propyl]-succinimides.
    Obniska J, Chlebek I, Kamiński K, Bojarski AJ, Satała G.
    Pharmacol Rep; 2012 May 15; 64(2):326-35. PubMed ID: 22661183
    [Abstract] [Full Text] [Related]

  • 18. A new class of arylpiperazine derivatives: the library synthesis on SynPhase lanterns and biological evaluation on serotonin 5-HT(1A) and 5-HT(2A) receptors.
    Zajdel P, Subra G, Bojarski AJ, Duszyńska B, Pawłowski M, Martinez J.
    J Comb Chem; 2004 May 15; 6(5):761-7. PubMed ID: 15360211
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and 5-HT(1A), 5-HT(2A) receptor activity of new beta-tetralonohydantoins.
    Byrtus H, Pawłowski M, Czopek A, Bojarski AJ, Duszyńska B, Nowak G, Kłodzińska A, Tatarczyńska E, Wesołowska A, Chojnacka-Wójcik E.
    Eur J Med Chem; 2005 Aug 15; 40(8):820-9. PubMed ID: 16122584
    [Abstract] [Full Text] [Related]

  • 20. Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.
    Bojarski AJ, Paluchowska MH, Duszyńska B, Bugno R, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E.
    Bioorg Med Chem; 2006 Mar 01; 14(5):1391-402. PubMed ID: 16266808
    [Abstract] [Full Text] [Related]


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