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Journal Abstract Search

161 related items for PubMed ID: 16610800

  • 1. 2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists.
    Serby MD, Zhao H, Szczepankiewicz BG, Kosogof C, Xin Z, Liu B, Liu M, Nelson LT, Kaszubska W, Falls HD, Schaefer V, Bush EN, Shapiro R, Droz BA, Knourek-Segel VE, Fey TA, Brune ME, Beno DW, Turner TM, Collins CA, Jacobson PB, Sham HL, Liu G.
    J Med Chem; 2006 Apr 20; 49(8):2568-78. PubMed ID: 16610800
    [Abstract] [Full Text] [Related]

  • 2. Discovery and pharmacological evaluation of growth hormone secretagogue receptor antagonists.
    Xin Z, Serby MD, Zhao H, Kosogof C, Szczepankiewicz BG, Liu M, Liu B, Hutchins CW, Sarris KA, Hoff ED, Falls HD, Lin CW, Ogiela CA, Collins CA, Brune ME, Bush EN, Droz BA, Fey TA, Knourek-Segel VE, Shapiro R, Jacobson PB, Beno DW, Turner TM, Sham HL, Liu G.
    J Med Chem; 2006 Jul 27; 49(15):4459-69. PubMed ID: 16854051
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  • 3. Optimization of 2,4-diaminopyrimidines as GHS-R antagonists: side chain exploration.
    Liu B, Liu M, Xin Z, Zhao H, Serby MD, Kosogof C, Nelson LT, Szczepankiewicz BG, Kaszubska W, Schaefer VG, Falls HD, Lin CW, Collins CA, Sham HL, Liu G.
    Bioorg Med Chem Lett; 2006 Apr 01; 16(7):1864-8. PubMed ID: 16442284
    [Abstract] [Full Text] [Related]

  • 4. Characterization of ghrelin receptor activity in a rat pituitary cell line RC-4B/C.
    Falls HD, Dayton BD, Fry DG, Ogiela CA, Schaefer VG, Brodjian S, Reilly RM, Collins CA, Kaszubska W.
    J Mol Endocrinol; 2006 Aug 01; 37(1):51-62. PubMed ID: 16901923
    [Abstract] [Full Text] [Related]

  • 5. Novel isoxazole carboxamides as growth hormone secretagogue receptor (GHS-R) antagonists.
    Liu B, Liu G, Xin Z, Serby MD, Zhao H, Schaefer VG, Falls HD, Kaszubska W, Collins CA, Sham HL.
    Bioorg Med Chem Lett; 2004 Oct 18; 14(20):5223-6. PubMed ID: 15380232
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  • 6. Growth hormone secretagogue receptor antagonists as anti-obesity therapies? Still an open question.
    Zhao H, Liu G.
    Curr Opin Drug Discov Devel; 2006 Jul 18; 9(4):509-15. PubMed ID: 16889233
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  • 10. [Trp3, Arg5]-ghrelin(1-5) stimulates growth hormone secretion and food intake via growth hormone secretagogue (GHS) receptor.
    Ohinata K, Kobayashi K, Yoshikawa M.
    Peptides; 2006 Jul 18; 27(7):1632-7. PubMed ID: 16530883
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  • 11. Unacylated ghrelin is not a functional antagonist but a full agonist of the type 1a growth hormone secretagogue receptor (GHS-R).
    Gauna C, van de Zande B, van Kerkwijk A, Themmen AP, van der Lely AJ, Delhanty PJ.
    Mol Cell Endocrinol; 2007 Aug 15; 274(1-2):30-4. PubMed ID: 17601657
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  • 12. Ghrelin control of GH secretion and feeding behaviour: the role of the GHS-R1a receptor studied in vivo and in vitro using novel non-peptide ligands.
    Bresciani E, Tamiazzo L, Torsello A, Bulgarelli I, Rapetti D, Caporali S, Perrissoud D, Moulin A, Fehrentz JA, Martinez J, Locatelli V.
    Eat Weight Disord; 2008 Sep 15; 13(3):e67-74. PubMed ID: 19011367
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  • 13. Quinazolinone derivatives as orally available ghrelin receptor antagonists for the treatment of diabetes and obesity.
    Rudolph J, Esler WP, O'connor S, Coish PD, Wickens PL, Brands M, Bierer DE, Bloomquist BT, Bondar G, Chen L, Chuang CY, Claus TH, Fathi Z, Fu W, Khire UR, Kristie JA, Liu XG, Lowe DB, McClure AC, Michels M, Ortiz AA, Ramsden PD, Schoenleber RW, Shelekhin TE, Vakalopoulos A, Tang W, Wang L, Yi L, Gardell SJ, Livingston JN, Sweet LJ, Bullock WH.
    J Med Chem; 2007 Oct 18; 50(21):5202-16. PubMed ID: 17887659
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  • 14. Anorexigenic and electrophysiological actions of novel ghrelin receptor (GHS-R1A) antagonists in rats.
    Salomé N, Haage D, Perrissoud D, Moulin A, Demange L, Egecioglu E, Fehrentz JA, Martinez J, Dickson SL.
    Eur J Pharmacol; 2009 Jun 10; 612(1-3):167-73. PubMed ID: 19356720
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  • 15. Heterogeneity of ghrelin/growth hormone secretagogue receptors. Toward the understanding of the molecular identity of novel ghrelin/GHS receptors.
    Muccioli G, Baragli A, Granata R, Papotti M, Ghigo E.
    Neuroendocrinology; 2007 Jun 10; 86(3):147-64. PubMed ID: 17622734
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  • 17. Toward potent ghrelin receptor ligands based on trisubstituted 1,2,4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations.
    Moulin A, Demange L, Bergé G, Gagne D, Ryan J, Mousseaux D, Heitz A, Perrissoud D, Locatelli V, Torsello A, Galleyrand JC, Fehrentz JA, Martinez J.
    J Med Chem; 2007 Nov 15; 50(23):5790-806. PubMed ID: 17927165
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  • 18. Effects of ghrelin on anorexia in tumor-bearing mice with eicosanoid-related cachexia.
    Wang W, Andersson M, Iresjö BM, Lönnroth C, Lundholm K.
    Int J Oncol; 2006 Jun 15; 28(6):1393-400. PubMed ID: 16685441
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  • 19. Synthesis and structure-activity relationships of isoxazole carboxamides as growth hormone secretagogue receptor antagonists.
    Xin Z, Zhao H, Serby MD, Liu B, Schaefer VG, Falls DH, Kaszubska W, Colins CA, Sham HL, Liu G.
    Bioorg Med Chem Lett; 2005 Feb 15; 15(4):1201-4. PubMed ID: 15686942
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  • 20. Recent developments in ghrelin receptor ligands.
    Moulin A, Ryan J, Martinez J, Fehrentz JA.
    ChemMedChem; 2007 Sep 15; 2(9):1242-59. PubMed ID: 17520591
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