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236 related items for PubMed ID: 16611247

  • 1. Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.
    Takizawa S, Nagasaka K, Nakagawa S, Yano T, Nakagawa K, Yasugi T, Takeuchi T, Kanda T, Huibregtse JM, Akiyama T, Taketani Y.
    Genes Cells; 2006 Apr; 11(4):453-64. PubMed ID: 16611247
    [Abstract] [Full Text] [Related]

  • 2. Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase.
    Nakagawa S, Huibregtse JM.
    Mol Cell Biol; 2000 Nov; 20(21):8244-53. PubMed ID: 11027293
    [Abstract] [Full Text] [Related]

  • 3. Involvement of a cellular ubiquitin-protein ligase E6AP in the ubiquitin-mediated degradation of extensive substrates of high-risk human papillomavirus E6.
    Matsumoto Y, Nakagawa S, Yano T, Takizawa S, Nagasaka K, Nakagawa K, Minaguchi T, Wada O, Ooishi H, Matsumoto K, Yasugi T, Kanda T, Huibregtse JM, Taketani Y.
    J Med Virol; 2006 Apr; 78(4):501-7. PubMed ID: 16482544
    [Abstract] [Full Text] [Related]

  • 4. Human homolog of Drosophila tumor suppressor Scribble negatively regulates cell-cycle progression from G1 to S phase by localizing at the basolateral membrane in epithelial cells.
    Nagasaka K, Nakagawa S, Yano T, Takizawa S, Matsumoto Y, Tsuruga T, Nakagawa K, Minaguchi T, Oda K, Hiraike-Wada O, Ooishi H, Yasugi T, Taketani Y.
    Cancer Sci; 2006 Nov; 97(11):1217-25. PubMed ID: 16965391
    [Abstract] [Full Text] [Related]

  • 5. Human papillomavirus type 16 E6 protein interacts with cystic fibrosis transmembrane regulator-associated ligand and promotes E6-associated protein-mediated ubiquitination and proteasomal degradation.
    Jeong KW, Kim HZ, Kim S, Kim YS, Choe J.
    Oncogene; 2007 Jan 25; 26(4):487-99. PubMed ID: 16878151
    [Abstract] [Full Text] [Related]

  • 6. Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix.
    Nakagawa S, Yano T, Nakagawa K, Takizawa S, Suzuki Y, Yasugi T, Huibregtse JM, Taketani Y.
    Br J Cancer; 2004 Jan 12; 90(1):194-9. PubMed ID: 14710229
    [Abstract] [Full Text] [Related]

  • 7. HPV E6 degradation of p53 and PDZ containing substrates in an E6AP null background.
    Massimi P, Shai A, Lambert P, Banks L.
    Oncogene; 2008 Mar 13; 27(12):1800-4. PubMed ID: 17934525
    [Abstract] [Full Text] [Related]

  • 8. Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein.
    Lee SS, Weiss RS, Javier RT.
    Proc Natl Acad Sci U S A; 1997 Jun 24; 94(13):6670-5. PubMed ID: 9192623
    [Abstract] [Full Text] [Related]

  • 9. A functional network of the tumor suppressors APC, hDlg, and PTEN, that relies on recognition of specific PDZ-domains.
    Sotelo NS, Valiente M, Gil A, Pulido R.
    J Cell Biochem; 2012 Aug 24; 113(8):2661-70. PubMed ID: 22434720
    [Abstract] [Full Text] [Related]

  • 10. Activity of the human papillomavirus E6 PDZ-binding motif correlates with an enhanced morphological transformation of immortalized human keratinocytes.
    Watson RA, Thomas M, Banks L, Roberts S.
    J Cell Sci; 2003 Dec 15; 116(Pt 24):4925-34. PubMed ID: 14625386
    [Abstract] [Full Text] [Related]

  • 11. The high-risk HPV E6 target scribble (hScrib) is required for HPV E6 expression in cervical tumour-derived cell lines.
    Kranjec C, Tomaić V, Massimi P, Nicolaides L, Doorbar J, Banks L.
    Papillomavirus Res; 2016 Dec 15; 2():70-77. PubMed ID: 29074188
    [Abstract] [Full Text] [Related]

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  • 14. Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein.
    Kiyono T, Hiraiwa A, Fujita M, Hayashi Y, Akiyama T, Ishibashi M.
    Proc Natl Acad Sci U S A; 1997 Oct 14; 94(21):11612-6. PubMed ID: 9326658
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  • 16. Human papillomavirus E6-induced degradation of E6TP1 is mediated by E6AP ubiquitin ligase.
    Gao Q, Kumar A, Singh L, Huibregtse JM, Beaudenon S, Srinivasan S, Wazer DE, Band H, Band V.
    Cancer Res; 2002 Jun 01; 62(11):3315-21. PubMed ID: 12036950
    [Abstract] [Full Text] [Related]

  • 17. Structures of a human papillomavirus (HPV) E6 polypeptide bound to MAGUK proteins: mechanisms of targeting tumor suppressors by a high-risk HPV oncoprotein.
    Zhang Y, Dasgupta J, Ma RZ, Banks L, Thomas M, Chen XS.
    J Virol; 2007 Apr 01; 81(7):3618-26. PubMed ID: 17267502
    [Abstract] [Full Text] [Related]

  • 18. HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation.
    Massimi P, Gammoh N, Thomas M, Banks L.
    Oncogene; 2004 Oct 21; 23(49):8033-9. PubMed ID: 15378012
    [Abstract] [Full Text] [Related]

  • 19. Adenomatous polyposis coli (APC) membrane recruitment 3, a member of the APC membrane recruitment family of APC-binding proteins, is a positive regulator of Wnt-β-catenin signalling.
    Brauburger K, Akyildiz S, Ruppert JG, Graeb M, Bernkopf DB, Hadjihannas MV, Behrens J.
    FEBS J; 2014 Feb 21; 281(3):787-801. PubMed ID: 24251807
    [Abstract] [Full Text] [Related]

  • 20. The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins.
    Thomas M, Massimi P, Navarro C, Borg JP, Banks L.
    Oncogene; 2005 Sep 15; 24(41):6222-30. PubMed ID: 16103886
    [Abstract] [Full Text] [Related]

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