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222 related items for PubMed ID: 16619521

  • 21. Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation.
    Brognard J, Clark AS, Ni Y, Dennis PA.
    Cancer Res; 2001 May 15; 61(10):3986-97. PubMed ID: 11358816
    [Abstract] [Full Text] [Related]

  • 22. Triptolide, a diterpenoid triepoxide, induces antitumor proliferation via activation of c-Jun NH2-terminal kinase 1 by decreasing phosphatidylinositol 3-kinase activity in human tumor cells.
    Miyata Y, Sato T, Ito A.
    Biochem Biophys Res Commun; 2005 Nov 04; 336(4):1081-6. PubMed ID: 16176806
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  • 23. 1,25-dihydroxyvitamin D(3) and PI3K/AKT inhibitors synergistically inhibit growth and induce senescence in prostate cancer cells.
    Axanova LS, Chen YQ, McCoy T, Sui G, Cramer SD.
    Prostate; 2010 Nov 01; 70(15):1658-71. PubMed ID: 20583132
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  • 24. Blockade of the epidermal growth factor receptor tyrosine kinase activity by quercetin and luteolin leads to growth inhibition and apoptosis of pancreatic tumor cells.
    Lee LT, Huang YT, Hwang JJ, Lee PP, Ke FC, Nair MP, Kanadaswam C, Lee MT.
    Anticancer Res; 2002 Nov 01; 22(3):1615-27. PubMed ID: 12168845
    [Abstract] [Full Text] [Related]

  • 25. Phosphatidylinositol 3-kinases inhibitor LY294002 potentiates the cytotoxic effects of doxorubicin, vincristine, and etoposide in a panel of cancer cell lines.
    Badinloo M, Esmaeili-Mahani S.
    Fundam Clin Pharmacol; 2014 Aug 01; 28(4):414-22. PubMed ID: 23837575
    [Abstract] [Full Text] [Related]

  • 26. Modulation of curcumin-induced Akt phosphorylation and apoptosis by PI3K inhibitor in MCF-7 cells.
    Kizhakkayil J, Thayyullathil F, Chathoth S, Hago A, Patel M, Galadari S.
    Biochem Biophys Res Commun; 2010 Apr 09; 394(3):476-81. PubMed ID: 20138829
    [Abstract] [Full Text] [Related]

  • 27. The involvement of phosphatidylinositol 3-kinase in gonadotropin-releasing hormone-induced gonadotropin alpha- and FSHbeta-subunit genes expression in clonal gonadotroph LbetaT2 cells.
    Mutiara S, Kanasaki H, Harada T, Oride A, Miyazaki K.
    Mol Cell Endocrinol; 2008 Feb 13; 283(1-2):1-11. PubMed ID: 18206295
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  • 28. Growth factor-stimulated phosphorylation of Akt and p70(S6K) is differentially inhibited by LY294002 and Wortmannin.
    Adi S, Wu NY, Rosenthal SM.
    Endocrinology; 2001 Jan 13; 142(1):498-501. PubMed ID: 11145615
    [Abstract] [Full Text] [Related]

  • 29. Tetraarsenic oxide-induced inhibition of malignant glioma cell invasion in vitro via a decrease in matrix metalloproteinase secretion and protein kinase B phosphorylation.
    Gwak HS, Park MJ, Park IC, Woo SH, Jin HO, Rhee CH, Jung HW.
    J Neurosurg; 2014 Dec 13; 121(6):1483-91. PubMed ID: 25303017
    [Abstract] [Full Text] [Related]

  • 30. Tumour suppressor PTEN regulates cell cycle and protein kinase B/Akt pathway in breast cancer cells.
    Hlobilkova A, Knillova J, Svachova M, Skypalova P, Krystof V, Kolar Z.
    Anticancer Res; 2006 Dec 13; 26(2A):1015-22. PubMed ID: 16619501
    [Abstract] [Full Text] [Related]

  • 31. PTEN Regulates Renal Extracellular Matrix Deposit via Increased CTGF in Diabetes Mellitus.
    Zhu L, Zhao S, Liu S, Liu Q, Li F, Hao J.
    J Cell Biochem; 2016 May 13; 117(5):1187-98. PubMed ID: 26447680
    [Abstract] [Full Text] [Related]

  • 32. Involvement of PI 3 kinase/Akt-dependent Bad phosphorylation in Toxoplasma gondii-mediated inhibition of host cell apoptosis.
    Quan JH, Cha GH, Zhou W, Chu JQ, Nishikawa Y, Lee YH.
    Exp Parasitol; 2013 Apr 13; 133(4):462-71. PubMed ID: 23333591
    [Abstract] [Full Text] [Related]

  • 33. Dual inhibition of PI3K and mTOR mitigates compensatory AKT activation and improves tamoxifen response in breast cancer.
    Chen X, Zhao M, Hao M, Sun X, Wang J, Mao Y, Zu L, Liu J, Shen Y, Wang J, Shen K.
    Mol Cancer Res; 2013 Oct 13; 11(10):1269-78. PubMed ID: 23814023
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  • 34. PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis.
    Fang J, Ding M, Yang L, Liu LZ, Jiang BH.
    Cell Signal; 2007 Dec 13; 19(12):2487-97. PubMed ID: 17826033
    [Abstract] [Full Text] [Related]

  • 35. The in vitro and in vivo effects of 2-(4-morpholinyl)-8-phenyl-chromone (LY294002), a specific inhibitor of phosphatidylinositol 3'-kinase, in human colon cancer cells.
    Semba S, Itoh N, Ito M, Harada M, Yamakawa M.
    Clin Cancer Res; 2002 Jun 13; 8(6):1957-63. PubMed ID: 12060641
    [Abstract] [Full Text] [Related]

  • 36. Loss of PTEN expression does not contribute to PDK-1 activity and PKC activation-loop phosphorylation in Jurkat leukaemic T cells.
    Freeley M, Park J, Yang KJ, Wange RL, Volkov Y, Kelleher D, Long A.
    Cell Signal; 2007 Dec 13; 19(12):2444-57. PubMed ID: 17826953
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  • 37. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL.
    Cancer Res; 2000 Mar 15; 60(6):1541-5. PubMed ID: 10749120
    [Abstract] [Full Text] [Related]

  • 38. Regulation of protein kinase B activity by PTEN and SHIP2 in human prostate-derived cell lines.
    Sharrard RM, Maitland NJ.
    Cell Signal; 2007 Jan 15; 19(1):129-38. PubMed ID: 16842970
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  • 39. Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells.
    Tabellini G, Cappellini A, Tazzari PL, Falà F, Billi AM, Manzoli L, Cocco L, Martelli AM.
    J Cell Physiol; 2005 Feb 15; 202(2):623-34. PubMed ID: 15316930
    [Abstract] [Full Text] [Related]

  • 40. Soluble epoxide hydrolase inhibition ameliorates proteinuria-induced epithelial-mesenchymal transition by regulating the PI3K-Akt-GSK-3β signaling pathway.
    Liang Y, Jing Z, Deng H, Li Z, Zhuang Z, Wang S, Wang Y.
    Biochem Biophys Res Commun; 2005 Feb 15; 463(1-2):70-5. PubMed ID: 25986738
    [Abstract] [Full Text] [Related]


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