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Journal Abstract Search

157 related items for PubMed ID: 16620789

  • 1. Radiolytic and cellular reduction of a novel hypoxia-activated cobalt(III) prodrug of a chloromethylbenzindoline DNA minor groove alkylator.
    Ahn GO, Botting KJ, Patterson AV, Ware DC, Tercel M, Wilson WR.
    Biochem Pharmacol; 2006 Jun 14; 71(12):1683-94. PubMed ID: 16620789
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  • 3. Optimization of the auxiliary ligand shell of Cobalt(III)(8-hydroxyquinoline) complexes as model hypoxia-selective radiation-activated prodrugs.
    Ahn GO, Ware DC, Denny WA, Wilson WR.
    Radiat Res; 2004 Sep 14; 162(3):315-25. PubMed ID: 15333003
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  • 8. Cross-bridged cyclen or cyclam Co(III) complexes containing cytotoxic ligands as hypoxia-activated prodrugs.
    Chang JY, Lu GL, Stevenson RJ, Brothers PJ, Clark GR, Botting KJ, Ferry DM, Tercel M, Wilson WR, Denny WA, Ware DC.
    Inorg Chem; 2013 Jul 01; 52(13):7688-98. PubMed ID: 23773210
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  • 11. Nitro-chloromethylbenzindolines: hypoxia-activated prodrugs of potent adenine N3 DNA minor groove alkylators.
    Wilson WR, Stribbling SM, Pruijn FB, Syddall SP, Patterson AV, Liyanage HD, Smith E, Botting KJ, Tercel M.
    Mol Cancer Ther; 2009 Oct 01; 8(10):2903-13. PubMed ID: 19808982
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  • 12. The flavoprotein FOXRED2 reductively activates nitro-chloromethylbenzindolines and other hypoxia-targeting prodrugs.
    Hunter FW, Jaiswal JK, Hurley DG, Liyanage HD, McManaway SP, Gu Y, Richter S, Wang J, Tercel M, Print CG, Wilson WR, Pruijn FB.
    Biochem Pharmacol; 2014 May 15; 89(2):224-35. PubMed ID: 24632291
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  • 13. Hypoxic selectivity and solubility--investigating the properties of A-ring substituted nitro seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-ones (nitroCBIs) as hypoxia-activated prodrugs for antitumor therapy.
    Tercel M, Yang S, Atwell GJ, Smith E, Gu Y, Anderson RF, Denny WA, Wilson WR, Pruijn FB.
    Bioorg Med Chem; 2010 Jul 15; 18(14):4997-5006. PubMed ID: 20580559
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  • 14. Cytotoxic palladium complexes of bioreductive quinoxaline N1,N4-dioxide prodrugs.
    Urquiola C, Vieites M, Torre MH, Cabrera M, Lavaggi ML, Cerecetto H, González M, Cerain AL, Monge A, Smircich P, Garat B, Gambino D.
    Bioorg Med Chem; 2009 Feb 15; 17(4):1623-9. PubMed ID: 19162490
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  • 15. Nitro seco analogues of the duocarmycins containing sulfonate leaving groups as hypoxia-activated prodrugs for cancer therapy.
    Stevenson RJ, Denny WA, Tercel M, Pruijn FB, Ashoorzadeh A.
    J Med Chem; 2012 Mar 22; 55(6):2780-802. PubMed ID: 22339090
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  • 16. The effect of a bromide leaving group on the properties of nitro analogs of the duocarmycins as hypoxia-activated prodrugs and phosphate pre-prodrugs for antitumor therapy.
    Stevenson RJ, Denny WA, Ashoorzadeh A, Pruijn FB, van Leeuwen WF, Tercel M.
    Bioorg Med Chem; 2011 Oct 15; 19(20):5989-98. PubMed ID: 21920763
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  • 17. DNA cross-links in human tumor cells exposed to the prodrug PR-104A: relationships to hypoxia, bioreductive metabolism, and cytotoxicity.
    Singleton RS, Guise CP, Ferry DM, Pullen SM, Dorie MJ, Brown JM, Patterson AV, Wilson WR.
    Cancer Res; 2009 May 01; 69(9):3884-91. PubMed ID: 19366798
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  • 18. Cobalt(III) Chaperone Complexes of Curcumin: Photoreduction, Cellular Accumulation and Light-Selective Toxicity towards Tumour Cells.
    Renfrew AK, Bryce NS, Hambley T.
    Chemistry; 2015 Oct 19; 21(43):15224-34. PubMed ID: 26471438
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  • 19. Synthesis, characterization and biological activities of mononuclear Co(III) complexes as potential bioreductively activated prodrugs.
    Souza ET, Castro LC, Castro FA, do Canto Visentin L, Pinheiro CB, Pereira MD, de Paula Machado S, Scarpellini M.
    J Inorg Biochem; 2009 Oct 19; 103(10):1355-65. PubMed ID: 19665800
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  • 20. Azido- and chlorido-cobalt complex as carrier-prototypes for antitumoral prodrugs.
    Pires BM, Giacomin LC, Castro FA, Cavalcanti Ados S, Pereira MD, Bortoluzzi AJ, Faria RB, Scarpellini M.
    J Inorg Biochem; 2016 Apr 19; 157():104-13. PubMed ID: 26881993
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