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421 related items for PubMed ID: 16620965

  • 1. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
    Zatti G, Burgo A, Giacomello M, Barbiero L, Ghidoni R, Sinigaglia G, Florean C, Bagnoli S, Binetti G, Sorbi S, Pizzo P, Fasolato C.
    Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
    [Abstract] [Full Text] [Related]

  • 2. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.
    J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846
    [Abstract] [Full Text] [Related]

  • 3. Decreased Abeta secretion by cells expressing familial Alzheimer's disease-linked mutant presenilin 1.
    Shimojo M, Sahara N, Murayama M, Ichinose H, Takashima A.
    Neurosci Res; 2007 Mar 15; 57(3):446-53. PubMed ID: 17210196
    [Abstract] [Full Text] [Related]

  • 4. The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells.
    Lessard CB, Lussier MP, Cayouette S, Bourque G, Boulay G.
    Cell Signal; 2005 Apr 15; 17(4):437-45. PubMed ID: 15601622
    [Abstract] [Full Text] [Related]

  • 5. Familial Alzheimer's disease-linked presenilin mutants and intracellular Ca2+ handling: A single-organelle, FRET-based analysis.
    Greotti E, Capitanio P, Wong A, Pozzan T, Pizzo P, Pendin D.
    Cell Calcium; 2019 May 15; 79():44-56. PubMed ID: 30822648
    [Abstract] [Full Text] [Related]

  • 6. Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.
    Rivabene R, Visentin S, Piscopo P, De Nuccio C, Crestini A, Svetoni F, Rosa P, Confaloni A.
    Exp Biol Med (Maywood); 2014 Feb 15; 239(2):213-24. PubMed ID: 24363250
    [Abstract] [Full Text] [Related]

  • 7. Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.
    Walker ES, Martinez M, Brunkan AL, Goate A.
    J Neurochem; 2005 Jan 15; 92(2):294-301. PubMed ID: 15663477
    [Abstract] [Full Text] [Related]

  • 8. Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.
    Ryazantseva M, Skobeleva K, Glushankova L, Kaznacheyeva E.
    J Neurochem; 2016 Mar 15; 136(5):1085-95. PubMed ID: 26678016
    [Abstract] [Full Text] [Related]

  • 9. Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome.
    Marambaud P, Alves da Costa C, Ancolio K, Checler F.
    Biochem Biophys Res Commun; 1998 Nov 09; 252(1):134-8. PubMed ID: 9813158
    [Abstract] [Full Text] [Related]

  • 10. Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.
    Tu H, Nelson O, Bezprozvanny A, Wang Z, Lee SF, Hao YH, Serneels L, De Strooper B, Yu G, Bezprozvanny I.
    Cell; 2006 Sep 08; 126(5):981-93. PubMed ID: 16959576
    [Abstract] [Full Text] [Related]

  • 11. Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2.
    Kipanyula MJ, Contreras L, Zampese E, Lazzari C, Wong AK, Pizzo P, Fasolato C, Pozzan T.
    Aging Cell; 2012 Oct 08; 11(5):885-93. PubMed ID: 22805202
    [Abstract] [Full Text] [Related]

  • 12. Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants.
    Hashimoto Y, Tsukamoto E, Niikura T, Yamagishi Y, Ishizaka M, Aiso S, Takashima A, Nishimoto I.
    J Neurosci Res; 2004 Feb 01; 75(3):417-28. PubMed ID: 14743455
    [Abstract] [Full Text] [Related]

  • 13. Modeling familial Alzheimer's disease with induced pluripotent stem cells.
    Yagi T, Ito D, Okada Y, Akamatsu W, Nihei Y, Yoshizaki T, Yamanaka S, Okano H, Suzuki N.
    Hum Mol Genet; 2011 Dec 01; 20(23):4530-9. PubMed ID: 21900357
    [Abstract] [Full Text] [Related]

  • 14. Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.
    Das HK, Tchedre K, Mueller B.
    J Neurochem; 2012 Aug 01; 122(3):487-500. PubMed ID: 22607268
    [Abstract] [Full Text] [Related]

  • 15. Presenilins as endoplasmic reticulum calcium leak channels and Alzheimer's disease pathogenesis.
    Supnet C, Bezprozvanny I.
    Sci China Life Sci; 2011 Aug 01; 54(8):744-51. PubMed ID: 21786197
    [Abstract] [Full Text] [Related]

  • 16. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.
    Nat Cell Biol; 1999 Dec 01; 1(8):479-85. PubMed ID: 10587643
    [Abstract] [Full Text] [Related]

  • 17. NF-kappaB activated by ER calcium release inhibits Abeta-mediated expression of CHOP protein: enhancement by AD-linked mutant presenilin 1.
    Schapansky J, Olson K, Van Der Ploeg R, Glazner G.
    Exp Neurol; 2007 Dec 01; 208(2):169-76. PubMed ID: 17927985
    [Abstract] [Full Text] [Related]

  • 18. Presenilin dependence of phospholipase C and protein kinase C signaling.
    Dehvari N, Cedazo-Minguez A, Isacsson O, Nilsson T, Winblad B, Karlström H, Benedikz E, Cowburn RF.
    J Neurochem; 2007 Aug 01; 102(3):848-57. PubMed ID: 17437536
    [Abstract] [Full Text] [Related]

  • 19. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice.
    Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, Younkin LH, DeGasperi R, Gama Sosa MA, Robakis NK, Haroutunian V, Elder GA.
    Exp Neurol; 2004 Aug 01; 188(2):224-37. PubMed ID: 15246822
    [Abstract] [Full Text] [Related]

  • 20. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
    Shirotani K, Tomioka M, Kremmer E, Haass C, Steiner H.
    Neurobiol Dis; 2007 Jul 01; 27(1):102-7. PubMed ID: 17560791
    [Abstract] [Full Text] [Related]

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