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486 related items for PubMed ID: 16620965

  • 21. Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels.
    Shilling D, Mak DO, Kang DE, Foskett JK.
    J Biol Chem; 2012 Mar 30; 287(14):10933-44. PubMed ID: 22311977
    [Abstract] [Full Text] [Related]

  • 22. [Presenilins as a marker of Alzheimer's disease].
    Scheper W, van Gool WA.
    Ned Tijdschr Geneeskd; 1998 May 30; 142(22):1247-52. PubMed ID: 9749296
    [Abstract] [Full Text] [Related]

  • 23. Is Alzheimer's disease a disorder of mitochondria-associated membranes?
    Schon EA, Area-Gomez E.
    J Alzheimers Dis; 2010 May 30; 20 Suppl 2():S281-92. PubMed ID: 20421691
    [Abstract] [Full Text] [Related]

  • 24. Presenilin 1 deficiency alters the activity of voltage-gated Ca2+ channels in cultured cortical neurons.
    Cook DG, Li X, Cherry SD, Cantrell AR.
    J Neurophysiol; 2005 Dec 30; 94(6):4421-9. PubMed ID: 16148264
    [Abstract] [Full Text] [Related]

  • 25. Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.
    Sato N, Urano F, Yoon Leem J, Kim SH, Li M, Donoviel D, Bernstein A, Lee AS, Ron D, Veselits ML, Sisodia SS, Thinakaran G.
    Nat Cell Biol; 2000 Dec 30; 2(12):863-70. PubMed ID: 11146649
    [Abstract] [Full Text] [Related]

  • 26. Calcium Signaling and Mitochondrial Function in Presenilin 2 Knock-Out Mice: Looking for Any Loss-of-Function Phenotype Related to Alzheimer's Disease.
    Rossi A, Galla L, Gomiero C, Zentilin L, Giacca M, Giorgio V, Calì T, Pozzan T, Greotti E, Pizzo P.
    Cells; 2021 Jan 21; 10(2):. PubMed ID: 33494218
    [Abstract] [Full Text] [Related]

  • 27. The presenilin 2 M239I mutation associated with familial Alzheimer's disease reduces Ca2+ release from intracellular stores.
    Zatti G, Ghidoni R, Barbiero L, Binetti G, Pozzan T, Fasolato C, Pizzo P.
    Neurobiol Dis; 2004 Mar 21; 15(2):269-78. PubMed ID: 15006697
    [Abstract] [Full Text] [Related]

  • 28. Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis.
    Zhang Z, Hartmann H, Do VM, Abramowski D, Sturchler-Pierrat C, Staufenbiel M, Sommer B, van de Wetering M, Clevers H, Saftig P, De Strooper B, He X, Yankner BA.
    Nature; 1998 Oct 15; 395(6703):698-702. PubMed ID: 9790190
    [Abstract] [Full Text] [Related]

  • 29. Presenilin-1 mutations associated with familial Alzheimer's disease do not disrupt protein transport from the endoplasmic reticulum to the Golgi apparatus.
    Tan Y, Hong J, Doan T, McConlogue L, Maltese WA.
    Biochim Biophys Acta; 1998 Jul 01; 1407(1):69-78. PubMed ID: 9639678
    [Abstract] [Full Text] [Related]

  • 30. Familial Alzheimer disease-linked mutations specifically disrupt Ca2+ leak function of presenilin 1.
    Nelson O, Tu H, Lei T, Bentahir M, de Strooper B, Bezprozvanny I.
    J Clin Invest; 2007 May 01; 117(5):1230-9. PubMed ID: 17431506
    [Abstract] [Full Text] [Related]

  • 31. Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse.
    Chen Q, Nakajima A, Choi SH, Xiong X, Tang YP.
    J Neurosci Res; 2008 May 15; 86(7):1615-25. PubMed ID: 18189321
    [Abstract] [Full Text] [Related]

  • 32. Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).
    Kuzuya A, Uemura K, Kitagawa N, Aoyagi N, Kihara T, Ninomiya H, Ishiura S, Takahashi R, Shimohama S.
    J Neurosci Res; 2007 Jan 15; 85(1):153-65. PubMed ID: 17075903
    [Abstract] [Full Text] [Related]

  • 33. Familial Alzheimer's disease presenilin 1 mutation M146V increases gamma secretase cutting of p75NTR in vitro.
    Hatchett CS, Tyler S, Armstrong D, Dawbarn D, Allen SJ.
    Brain Res; 2007 May 25; 1147():248-55. PubMed ID: 17349981
    [Abstract] [Full Text] [Related]

  • 34. Novel role of presenilins in maturation and transport of integrin beta 1.
    Zou K, Hosono T, Nakamura T, Shiraishi H, Maeda T, Komano H, Yanagisawa K, Michikawa M.
    Biochemistry; 2008 Mar 18; 47(11):3370-8. PubMed ID: 18293935
    [Abstract] [Full Text] [Related]

  • 35. Up-regulation of inositol 1,4,5-trisphosphate receptor type 1 is responsible for a decreased endoplasmic-reticulum Ca2+ content in presenilin double knock-out cells.
    Kasri NN, Kocks SL, Verbert L, Hébert SS, Callewaert G, Parys JB, Missiaen L, De Smedt H.
    Cell Calcium; 2006 Jul 18; 40(1):41-51. PubMed ID: 16675011
    [Abstract] [Full Text] [Related]

  • 36. Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.
    Tong BC, Lee CS, Cheng WH, Lai KO, Foskett JK, Cheung KH.
    Sci Signal; 2016 Sep 06; 9(444):ra89. PubMed ID: 27601731
    [Abstract] [Full Text] [Related]

  • 37. Calcium release from the Golgi apparatus and the endoplasmic reticulum in HeLa cells stably expressing targeted aequorin to these compartments.
    Missiaen L, Van Acker K, Van Baelen K, Raeymaekers L, Wuytack F, Parys JB, De Smedt H, Vanoevelen J, Dode L, Rizzuto R, Callewaert G.
    Cell Calcium; 2004 Dec 06; 36(6):479-87. PubMed ID: 15488597
    [Abstract] [Full Text] [Related]

  • 38. Cell cycle-driven neuronal apoptosis specifically linked to amyloid peptide Abeta1-42 exposure is not exacerbated in a mouse model of presenilin-1 familial Alzheimer's disease.
    Malik B, Currais A, Soriano S.
    J Neurochem; 2008 Jul 06; 106(2):912-6. PubMed ID: 18466334
    [Abstract] [Full Text] [Related]

  • 39. Presenilin-2 dampens intracellular Ca2+ stores by increasing Ca2+ leakage and reducing Ca2+ uptake.
    Brunello L, Zampese E, Florean C, Pozzan T, Pizzo P, Fasolato C.
    J Cell Mol Med; 2009 Sep 06; 13(9B):3358-69. PubMed ID: 19382908
    [Abstract] [Full Text] [Related]

  • 40. Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice.
    Wen PH, Shao X, Shao Z, Hof PR, Wisniewski T, Kelley K, Friedrich VL, Ho L, Pasinetti GM, Shioi J, Robakis NK, Elder GA.
    Neurobiol Dis; 2002 Jun 06; 10(1):8-19. PubMed ID: 12079399
    [Abstract] [Full Text] [Related]


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