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PUBMED FOR HANDHELDS

Journal Abstract Search


89 related items for PubMed ID: 16624245

  • 1. Allosteric modulation of the human P-glycoprotein involves conformational changes mimicking catalytic transition intermediates.
    Ghosh P, Moitra K, Maki N, Dey S.
    Arch Biochem Biophys; 2006 Jun 01; 450(1):100-12. PubMed ID: 16624245
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  • 2. Modulator-induced interference in functional cross talk between the substrate and the ATP sites of human P-glycoprotein.
    Maki N, Moitra K, Silver C, Ghosh P, Chattopadhyay A, Dey S.
    Biochemistry; 2006 Feb 28; 45(8):2739-51. PubMed ID: 16489767
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  • 5. Allosteric modulation bypasses the requirement for ATP hydrolysis in regenerating low affinity transition state conformation of human P-glycoprotein.
    Maki N, Moitra K, Ghosh P, Dey S.
    J Biol Chem; 2006 Apr 21; 281(16):10769-77. PubMed ID: 16505485
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  • 8. Nucleotide binding, ATP hydrolysis, and mutation of the catalytic carboxylates of human P-glycoprotein cause distinct conformational changes in the transmembrane segments.
    Loo TW, Bartlett MC, Clarke DM.
    Biochemistry; 2007 Aug 14; 46(32):9328-36. PubMed ID: 17636884
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  • 10. Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state.
    Ramachandra M, Ambudkar SV, Chen D, Hrycyna CA, Dey S, Gottesman MM, Pastan I.
    Biochemistry; 1998 Apr 07; 37(14):5010-9. PubMed ID: 9538020
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  • 12. Gomisin A alters substrate interaction and reverses P-glycoprotein-mediated multidrug resistance in HepG2-DR cells.
    Wan CK, Zhu GY, Shen XL, Chattopadhyay A, Dey S, Fong WF.
    Biochem Pharmacol; 2006 Sep 28; 72(7):824-37. PubMed ID: 16889754
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  • 14. Stimulation of P-glycoprotein ATPase by analogues of tetramethylrosamine: coupling of drug binding at the "R" site to the ATP hydrolysis transition state.
    Tombline G, Donnelly DJ, Holt JJ, You Y, Ye M, Gannon MK, Nygren CL, Detty MR.
    Biochemistry; 2006 Jul 04; 45(26):8034-47. PubMed ID: 16800628
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  • 15. Catalytic mechanism of P-glycoprotein.
    Senior AE.
    Acta Physiol Scand Suppl; 1998 Aug 04; 643():213-8. PubMed ID: 9789563
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  • 17. Evidence for modulatory sites at the lipid-protein interface of the human multidrug transporter P-glycoprotein.
    Mandal D, Moitra K, Ghosh D, Xia D, Dey S.
    Biochemistry; 2012 Apr 03; 51(13):2852-66. PubMed ID: 22360349
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  • 18. Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Nagy H, Goda K, Fenyvesi F, Bacsó Z, Szilasi M, Kappelmayer J, Lustyik G, Cianfriglia M, Szabó G.
    Biochem Biophys Res Commun; 2004 Mar 19; 315(4):942-9. PubMed ID: 14985103
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  • 20. Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein.
    Dey S, Ramachandra M, Pastan I, Gottesman MM, Ambudkar SV.
    Proc Natl Acad Sci U S A; 1997 Sep 30; 94(20):10594-9. PubMed ID: 9380680
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