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265 related items for PubMed ID: 16648253
1. A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC. Lai JC, Tan W, Benimetskaya L, Miller P, Colombini M, Stein CA. Proc Natl Acad Sci U S A; 2006 May 09; 103(19):7494-9. PubMed ID: 16648253 [Abstract] [Full Text] [Related]
2. Phosphorothioate oligonucleotides reduce mitochondrial outer membrane permeability to ADP. Tan W, Lai JC, Miller P, Stein CA, Colombini M. Am J Physiol Cell Physiol; 2007 Apr 09; 292(4):C1388-97. PubMed ID: 17135295 [Abstract] [Full Text] [Related]
3. Phosphorothioate oligodeoxynucleotides and G3139 induce apoptosis in 518A2 melanoma cells. Lai JC, Benimetskaya L, Khvorova A, Wu S, Hua E, Miller P, Stein CA. Mol Cancer Ther; 2005 Feb 09; 4(2):305-15. PubMed ID: 15713901 [Abstract] [Full Text] [Related]
4. VDAC blockage by phosphorothioate oligonucleotides and its implication in apoptosis. Tan W. Biochim Biophys Acta; 2012 Jun 09; 1818(6):1555-61. PubMed ID: 22236836 [Abstract] [Full Text] [Related]
5. Bcl-2 protein in 518A2 melanoma cells in vivo and in vitro. Benimetskaya L, Ayyanar K, Kornblum N, Castanotto D, Rossi J, Wu S, Lai J, Brown BD, Popova N, Miller P, McMicken H, Chen Y, Stein CA. Clin Cancer Res; 2006 Aug 15; 12(16):4940-8. PubMed ID: 16914583 [Abstract] [Full Text] [Related]
6. Phosphorothioate oligonucleotides block the VDAC channel. Tan W, Loke YH, Stein CA, Miller P, Colombini M. Biophys J; 2007 Aug 15; 93(4):1184-91. PubMed ID: 17483171 [Abstract] [Full Text] [Related]
7. Combined effect of G3139 and TSPO ligands on Ca(2+)-induced permeability transition in rat brain mitochondria. Azarashvili T, Krestinina O, Baburina Y, Odinokova I, Grachev D, Papadopoulos V, Akatov V, Lemasters JJ, Reiser G. Arch Biochem Biophys; 2015 Dec 01; 587():70-7. PubMed ID: 26498031 [Abstract] [Full Text] [Related]
8. Closure of VDAC causes oxidative stress and accelerates the Ca(2+)-induced mitochondrial permeability transition in rat liver mitochondria. Tikunov A, Johnson CB, Pediaditakis P, Markevich N, Macdonald JM, Lemasters JJ, Holmuhamedov E. Arch Biochem Biophys; 2010 Mar 15; 495(2):174-81. PubMed ID: 20097153 [Abstract] [Full Text] [Related]
9. The voltage-dependent anion channel (VDAC): function in intracellular signalling, cell life and cell death. Shoshan-Barmatz V, Israelson A, Brdiczka D, Sheu SS. Curr Pharm Des; 2006 Mar 15; 12(18):2249-70. PubMed ID: 16787253 [Abstract] [Full Text] [Related]
10. VDAC regulation: role of cytosolic proteins and mitochondrial lipids. Rostovtseva TK, Bezrukov SM. J Bioenerg Biomembr; 2008 Jun 15; 40(3):163-70. PubMed ID: 18654841 [Abstract] [Full Text] [Related]
11. Induction of apoptosis by G3139 in melanoma cells. Benimetskaya L, Lai JC, Khvorova A, Wu S, Miller P, Stein CA. Ann N Y Acad Sci; 2005 Nov 15; 1058():235-45. PubMed ID: 16394140 [Abstract] [Full Text] [Related]
12. Relative Bcl-2 independence of drug-induced cytotoxicity and resistance in 518A2 melanoma cells. Benimetskaya L, Lai JC, Khvorova A, Wu S, Hua E, Miller P, Zhang LM, Stein CA. Clin Cancer Res; 2004 Dec 15; 10(24):8371-9. PubMed ID: 15623615 [Abstract] [Full Text] [Related]
13. Comparison of d-g3139 and its enantiomer L-g3139 in melanoma cells demonstrates minimal in vitro but dramatic in vivo chiral dependency. Lai JC, Brown BD, Voskresenskiy AM, Vonhoff S, Klussman S, Tan W, Colombini M, Weeratna R, Miller P, Benimetskaya L, Stein CA. Mol Ther; 2007 Feb 15; 15(2):270-8. PubMed ID: 17235304 [Abstract] [Full Text] [Related]
14. Essential role of the voltage-dependent anion channel (VDAC) in mitochondrial permeability transition pore opening and cytochrome c release induced by arsenic trioxide. Zheng Y, Shi Y, Tian C, Jiang C, Jin H, Chen J, Almasan A, Tang H, Chen Q. Oncogene; 2004 Feb 12; 23(6):1239-47. PubMed ID: 14647451 [Abstract] [Full Text] [Related]
15. G3139 (oblimersen) may inhibit prostate cancer cell growth in a partially bis-CpG-dependent non-antisense manner. Lai JC, Benimetskaya L, Santella RM, Wang Q, Miller PS, Stein CA. Mol Cancer Ther; 2003 Oct 12; 2(10):1031-43. PubMed ID: 14578468 [Abstract] [Full Text] [Related]
16. VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis. Veenman L, Shandalov Y, Gavish M. J Bioenerg Biomembr; 2008 Jun 12; 40(3):199-205. PubMed ID: 18670869 [Abstract] [Full Text] [Related]