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166 related items for PubMed ID: 16673403

  • 1. Metabolic GHB precursor succinate binds to gamma-hydroxybutyrate receptors: characterization of human basal ganglia areas nucleus accumbens and globus pallidus.
    Molnár T, Fekete EK, Kardos J, Simon-Trompler E, Palkovits M, Emri Z.
    J Neurosci Res; 2006 Jul; 84(1):27-36. PubMed ID: 16673403
    [Abstract] [Full Text] [Related]

  • 2. gamma-Hydroxybutyrate binds to the synaptic site recognizing succinate monocarboxylate: a new hypothesis on astrocyte-neuron interaction via the protonation of succinate.
    Molnár T, Barabás P, Héja L, Fekete EK, Lasztóczi B, Szabó P, Nyitrai G, Simon-Trompler E, Hajós F, Palkovits M, Kardos J.
    J Neurosci Res; 2008 May 15; 86(7):1566-76. PubMed ID: 18189322
    [Abstract] [Full Text] [Related]

  • 3. Characterization of specific succinate binding site in brain synaptic membranes.
    Molnár T, Fekete EK, Kardos J, Palkovits M.
    Ideggyogy Sz; 2007 Mar 30; 60(3-4):201-4. PubMed ID: 17451069
    [Abstract] [Full Text] [Related]

  • 4. gamma-Hydroxybutyrate (GHB) induces GABA(B) receptor independent intracellular Ca2+ transients in astrocytes, but has no effect on GHB or GABA(B) receptors of medium spiny neurons in the nucleus accumbens.
    Molnár T, Antal K, Nyitrai G, Emri Z.
    Neuroscience; 2009 Aug 18; 162(2):268-81. PubMed ID: 19446011
    [Abstract] [Full Text] [Related]

  • 5. Binding characteristics of the gamma-hydroxybutyric acid receptor antagonist [(3)H](2E)-(5-hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene) ethanoic acid in the rat brain.
    Mehta AK, Muschaweck NM, Maeda DY, Coop A, Ticku MK.
    J Pharmacol Exp Ther; 2001 Dec 18; 299(3):1148-53. PubMed ID: 11714906
    [Abstract] [Full Text] [Related]

  • 6. Characterization and pharmacology of the GHB receptor.
    Ticku MK, Mehta AK.
    Ann N Y Acad Sci; 2008 Oct 18; 1139():374-85. PubMed ID: 18991884
    [Abstract] [Full Text] [Related]

  • 7. The distribution of gamma-hydroxybutyrate-induced Fos expression in rat brain: comparison with baclofen.
    van Nieuwenhuijzen PS, McGregor IS, Hunt GE.
    Neuroscience; 2009 Jan 23; 158(2):441-55. PubMed ID: 18996447
    [Abstract] [Full Text] [Related]

  • 8. Relation of the [3H] gamma-hydroxybutyric acid (GHB) binding site to the gamma-aminobutyric acidB (GABAB) receptor in rat brain.
    Snead OC.
    Biochem Pharmacol; 1996 Oct 25; 52(8):1235-43. PubMed ID: 8937431
    [Abstract] [Full Text] [Related]

  • 9. The role of GABAB receptors in the discriminative stimulus effects of gamma-hydroxybutyrate in rats: time course and antagonism studies.
    Carter LP, Flores LR, Wu H, Chen W, Unzeitig AW, Coop A, France CP.
    J Pharmacol Exp Ther; 2003 May 25; 305(2):668-74. PubMed ID: 12606639
    [Abstract] [Full Text] [Related]

  • 10. Specific gamma-hydroxybutyrate-binding sites but loss of pharmacological effects of gamma-hydroxybutyrate in GABA(B)(1)-deficient mice.
    Kaupmann K, Cryan JF, Wellendorph P, Mombereau C, Sansig G, Klebs K, Schmutz M, Froestl W, van der Putten H, Mosbacher J, Bräuner-Osborne H, Waldmeier P, Bettler B.
    Eur J Neurosci; 2003 Nov 25; 18(10):2722-30. PubMed ID: 14656321
    [Abstract] [Full Text] [Related]

  • 11. gamma-hydroxybutyrate increases a potassium current and decreases the H-current in hippocampal neurons via GABAB receptors.
    Schweitzer P, Roberto M, Madamba SG, Siggins GR.
    J Pharmacol Exp Ther; 2004 Oct 25; 311(1):172-9. PubMed ID: 15152029
    [Abstract] [Full Text] [Related]

  • 12. Validation of high-affinity binding sites for succinic acid through distinguishable binding of gamma-hydroxybutyric acid receptor-specific NCS 382 antipodes.
    Molnár T, Visy J, Simon A, Moldvai I, Temesvári-Major E, Dörnyei G, Fekete EK, Kardos J.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6290-2. PubMed ID: 18945616
    [Abstract] [Full Text] [Related]

  • 13. The motor-impairing effects of GABA(A) and GABA(B) agonists in gamma-hydroxybutyrate (GHB)-treated rats: cross-tolerance to baclofen but not flunitrazepam.
    Smith MA, Gergans SR, Lyle MA.
    Eur J Pharmacol; 2006 Dec 15; 552(1-3):83-9. PubMed ID: 17026996
    [Abstract] [Full Text] [Related]

  • 14. A tertiary alcohol analog of gamma-hydroxybutyric acid as a specific gamma-hydroxybutyric acid receptor ligand.
    Wu H, Zink N, Carter LP, Mehta AK, Hernandez RJ, Ticku MK, Lamb R, France CP, Coop A.
    J Pharmacol Exp Ther; 2003 May 15; 305(2):675-9. PubMed ID: 12606613
    [Abstract] [Full Text] [Related]

  • 15. Binding characteristics of gamma-hydroxybutyric acid as a weak but selective GABAB receptor agonist.
    Mathivet P, Bernasconi R, De Barry J, Marescaux C, Bittiger H.
    Eur J Pharmacol; 1997 Feb 19; 321(1):67-75. PubMed ID: 9083788
    [Abstract] [Full Text] [Related]

  • 16. Succinic semialdehyde dehydrogenase deficiency: GABAB receptor-mediated function.
    Buzzi A, Wu Y, Frantseva MV, Perez Velazquez JL, Cortez MA, Liu CC, Shen LQ, Gibson KM, Snead OC.
    Brain Res; 2006 May 23; 1090(1):15-22. PubMed ID: 16647690
    [Abstract] [Full Text] [Related]

  • 17. Ethanol does not alter the binding of the gamma-hydroxybutyric acid (GHB) receptor ligand [3H]NCS-382 in the rat brain.
    Mehta AK, Muschaweck NM, Ticku MK.
    Drug Alcohol Depend; 2004 Sep 06; 75(3):323-5. PubMed ID: 15283953
    [Abstract] [Full Text] [Related]

  • 18. Selective gamma-hydroxybutyric acid receptor ligands increase extracellular glutamate in the hippocampus, but fail to activate G protein and to produce the sedative/hypnotic effect of gamma-hydroxybutyric acid.
    Castelli MP, Ferraro L, Mocci I, Carta F, Carai MA, Antonelli T, Tanganelli S, Cignarella G, Gessa GL.
    J Neurochem; 2003 Nov 06; 87(3):722-32. PubMed ID: 14535954
    [Abstract] [Full Text] [Related]

  • 19. Novel radioiodinated {gamma}-hydroxybutyric acid analogues for radiolabeling and Photolinking of high-affinity {gamma}-hydroxybutyric acid binding sites.
    Wellendorph P, Høg S, Sabbatini P, Pedersen MH, Martiny L, Knudsen GM, Frølund B, Clausen RP, Bräuner-Osborne H.
    J Pharmacol Exp Ther; 2010 Nov 06; 335(2):458-64. PubMed ID: 20696866
    [Abstract] [Full Text] [Related]

  • 20. Phenylacetic acids and the structurally related non-steroidal anti-inflammatory drug diclofenac bind to specific gamma-hydroxybutyric acid sites in rat brain.
    Wellendorph P, Høg S, Skonberg C, Bräuner-Osborne H.
    Fundam Clin Pharmacol; 2009 Apr 06; 23(2):207-13. PubMed ID: 19645815
    [Abstract] [Full Text] [Related]

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