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Journal Abstract Search

260 related items for PubMed ID: 16677080

  • 1.
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    [No Abstract] [Full Text] [Related]

  • 2. Site-directed mutagenesis of coumarin-type anticoagulant-sensitive VKORC1: evidence that highly conserved amino acids define structural requirements for enzymatic activity and inhibition by warfarin.
    Rost S, Fregin A, Hünerberg M, Bevans CG, Müller CR, Oldenburg J.
    Thromb Haemost; 2005 Oct; 94(4):780-6. PubMed ID: 16270630
    [Abstract] [Full Text] [Related]

  • 3. Vitamin K epoxide reductase: homology, active site and catalytic mechanism.
    Goodstadt L, Ponting CP.
    Trends Biochem Sci; 2004 Jun; 29(6):289-92. PubMed ID: 15276181
    [Abstract] [Full Text] [Related]

  • 4. VKORC1 and the vitamin K cycle.
    Garcia AA, Reitsma PH.
    Vitam Horm; 2008 Jun; 78():23-33. PubMed ID: 18374188
    [Abstract] [Full Text] [Related]

  • 5. Engineering of a recombinant vitamin K-dependent gamma-carboxylation system with enhanced gamma-carboxyglutamic acid forming capacity: evidence for a functional CXXC redox center in the system.
    Wajih N, Sane DC, Hutson SM, Wallin R.
    J Biol Chem; 2005 Mar 18; 280(11):10540-7. PubMed ID: 15640149
    [Abstract] [Full Text] [Related]

  • 6. Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.
    Rost S, Fregin A, Ivaskevicius V, Conzelmann E, Hörtnagel K, Pelz HJ, Lappegard K, Seifried E, Scharrer I, Tuddenham EG, Müller CR, Strom TM, Oldenburg J.
    Nature; 2004 Feb 05; 427(6974):537-41. PubMed ID: 14765194
    [Abstract] [Full Text] [Related]

  • 7. [New insight in therapeutic anticoagulation by Coumarin derivatives].
    Oldenburg J, Seidel H, Pötzsch B, Watzka M.
    Hamostaseologie; 2008 Feb 05; 28(1-2):44-50. PubMed ID: 18278162
    [Abstract] [Full Text] [Related]

  • 8. Structure and function of vitamin K epoxide reductase.
    Tie JK, Stafford DW.
    Vitam Horm; 2008 Feb 05; 78():103-30. PubMed ID: 18374192
    [Abstract] [Full Text] [Related]

  • 9. Phylogeny of the Vitamin K 2,3-Epoxide Reductase (VKOR) Family and Evolutionary Relationship to the Disulfide Bond Formation Protein B (DsbB) Family.
    Bevans CG, Krettler C, Reinhart C, Watzka M, Oldenburg J.
    Nutrients; 2015 Jul 29; 7(8):6224-49. PubMed ID: 26230708
    [Abstract] [Full Text] [Related]

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  • 11. Two enzymes catalyze vitamin K 2,3-epoxide reductase activity in mouse: VKORC1 is highly expressed in exocrine tissues while VKORC1L1 is highly expressed in brain.
    Caspers M, Czogalla KJ, Liphardt K, Müller J, Westhofen P, Watzka M, Oldenburg J.
    Thromb Res; 2015 May 29; 135(5):977-83. PubMed ID: 25747820
    [Abstract] [Full Text] [Related]

  • 12. VKORC1 deficiency in mice causes early postnatal lethality due to severe bleeding.
    Spohn G, Kleinridders A, Wunderlich FT, Watzka M, Zaucke F, Blumbach K, Geisen C, Seifried E, Müller C, Paulsson M, Brüning JC, Oldenburg J.
    Thromb Haemost; 2009 Jun 29; 101(6):1044-50. PubMed ID: 19492146
    [Abstract] [Full Text] [Related]

  • 13.
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  • 14. Structural and functional insights into enzymes of the vitamin K cycle.
    Tie JK, Stafford DW.
    J Thromb Haemost; 2016 Feb 29; 14(2):236-47. PubMed ID: 26663892
    [Abstract] [Full Text] [Related]

  • 15. Determination of the warfarin inhibition constant Ki for vitamin K 2,3-epoxide reductase complex subunit-1 (VKORC1) using an in vitro DTT-driven assay.
    Bevans CG, Krettler C, Reinhart C, Tran H, Koßmann K, Watzka M, Oldenburg J.
    Biochim Biophys Acta; 2013 Aug 29; 1830(8):4202-10. PubMed ID: 23618698
    [Abstract] [Full Text] [Related]

  • 16. Conserved loop cysteines of vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) are involved in its active site regeneration.
    Tie JK, Jin DY, Stafford DW.
    J Biol Chem; 2014 Mar 28; 289(13):9396-407. PubMed ID: 24532791
    [Abstract] [Full Text] [Related]

  • 17. [Vitamin K epoxide reductase: Fresh blood for oral anticoagulant therapies].
    Loriot MA, Beaune P.
    Rev Med Interne; 2006 Dec 28; 27(12):979-82. PubMed ID: 17070618
    [Abstract] [Full Text] [Related]

  • 18. Identification of the gene for vitamin K epoxide reductase.
    Li T, Chang CY, Jin DY, Lin PJ, Khvorova A, Stafford DW.
    Nature; 2004 Feb 05; 427(6974):541-4. PubMed ID: 14765195
    [Abstract] [Full Text] [Related]

  • 19. VKORC1: molecular target of coumarins.
    Oldenburg J, Watzka M, Rost S, Müller CR.
    J Thromb Haemost; 2007 Jul 05; 5 Suppl 1():1-6. PubMed ID: 17635701
    [Abstract] [Full Text] [Related]

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