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299 related items for PubMed ID: 16682206

  • 1. 4'-Fluorinated carbocyclic nucleosides: synthesis and inhibitory activity against S-adenosyl-L-homocysteine hydrolase.
    Kitade Y, Ando T, Yamaguchi T, Hori A, Nakanishi M, Ueno Y.
    Bioorg Med Chem; 2006 Aug 15; 14(16):5578-83. PubMed ID: 16682206
    [Abstract] [Full Text] [Related]

  • 2. Effects of 4'-modified analogs of aristeromycin on the metabolism of S-adenosyl-L-homocysteine in murine L929 cells.
    Ault-Riché DB, Lee Y, Yuan CS, Hasobe M, Wolfe MS, Borcherding DR, Borchardt RT.
    Mol Pharmacol; 1993 Jun 15; 43(6):989-97. PubMed ID: 8316227
    [Abstract] [Full Text] [Related]

  • 3. Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.
    Ando T, Iwata M, Zulfiqar F, Miyamoto T, Nakanishi M, Kitade Y.
    Bioorg Med Chem; 2008 Apr 01; 16(7):3809-15. PubMed ID: 18295495
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase.
    Ando T, Kojima K, Chahota P, Kozaki A, Milind ND, Kitade Y.
    Bioorg Med Chem Lett; 2008 Apr 15; 18(8):2615-8. PubMed ID: 18374570
    [Abstract] [Full Text] [Related]

  • 5. Synthesis of 5'-methylenearisteromycin and its 2-fluoro derivative with potent antimalarial activity due to inhibition of the parasite S-adenosylhomocysteine hydrolase.
    Takagi C, Sukeda M, Kim HS, Wataya Y, Yabe S, Kitade Y, Matsuda A, Shuto S.
    Org Biomol Chem; 2005 Apr 07; 3(7):1245-51. PubMed ID: 15785814
    [Abstract] [Full Text] [Related]

  • 6. Stereoselective synthesis of sugar-modified enyne analogues of adenosine and uridine. Interaction with S-adenosyl-L-homocysteine hydrolase and antiviral and cytotoxic effects.
    Wnuk SF, Lewandowska E, Sacasa PR, Crain LN, Zhang J, Borchardt RT, De Clercq E.
    J Med Chem; 2004 Oct 07; 47(21):5251-7. PubMed ID: 15456269
    [Abstract] [Full Text] [Related]

  • 7. S-Adenosyl-L-homocysteine hydrolase inhibitor mediates immunosuppressive effects in vivo: suppression of delayed type hypersensitivity ear swelling and peptidoglycan polysaccharide-induced arthritis.
    Saso Y, Conner EM, Teegarden BR, Yuan CS.
    J Pharmacol Exp Ther; 2001 Jan 07; 296(1):106-12. PubMed ID: 11123369
    [Abstract] [Full Text] [Related]

  • 8. Inactivation of S-adenosyl-L-homocysteine hydrolase by 6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine and 6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine. Antiviral and cytotoxic effects.
    Guillerm G, Muzard M, Glapski C, Pilard S, De Clercq E.
    J Med Chem; 2006 Feb 23; 49(4):1223-6. PubMed ID: 16480257
    [Abstract] [Full Text] [Related]

  • 9. Synthesis of 3',4'-epoxynoraristeromycin analogs for molecular labeling probe of S-adenosyl-l-homocysteine hydrolase.
    Kojima H, Kozaki A, Iwata M, Ando T, Kitade Y.
    Bioorg Med Chem; 2008 Jul 01; 16(13):6575-9. PubMed ID: 18515116
    [Abstract] [Full Text] [Related]

  • 10. Inactivation of S-adenosyl-L-homocysteine hydrolase and antiviral activity with 5',5',6',6'-tetradehydro-6'-deoxy-6'-halohomoadenosine analogues (4'-haloacetylene analogues derived from adenosine).
    Robins MJ, Wnuk SF, Yang X, Yuan CS, Borchardt RT, Balzarini J, De Clercq E.
    J Med Chem; 1998 Sep 24; 41(20):3857-64. PubMed ID: 9748360
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and antiviral activities of 3-deaza-3-fluoroaristeromycin and its 5' analogues.
    Chen Q, Liu C, Komazin G, Bowlin TL, Schneller SW.
    Bioorg Med Chem; 2014 Dec 15; 22(24):6961-4. PubMed ID: 25456389
    [Abstract] [Full Text] [Related]

  • 12. Synthesis of novel 4'-modified neplanocin A analogues and their inhibitory activity against S-adenosyl-L-l-homocysteine hydrolase.
    Kumamoto H, Deguchi K, Takahashi N, Tanaka H, Kitade Y.
    Nucleosides Nucleotides Nucleic Acids; 2007 Dec 15; 26(6-7):733-6. PubMed ID: 18066891
    [Abstract] [Full Text] [Related]

  • 13. Open-chain carbocyclic analogs of adenosine with dihalovinyl unit as potential inhibitors of S-adenosyl-L-homocysteine hydrolase.
    Lewandowska E, Lalama J, Yuan CS, Wnuk SF.
    Nucleosides Nucleotides Nucleic Acids; 2003 Sep 15; 22(9):1747-55. PubMed ID: 14533879
    [Abstract] [Full Text] [Related]

  • 14. Stereoselective synthesis of homo-apioneplanocin A as potential inhibitor of S-adenosylhomocysteine hydrolase.
    Chun MW, Lee HW, Kim JH, Kim HO, Lee KM, Pal S, Moon HR, Jeong LS.
    Nucleosides Nucleotides Nucleic Acids; 2007 Sep 15; 26(6-7):729-32. PubMed ID: 18066890
    [Abstract] [Full Text] [Related]

  • 15. Are L-adenosine and its derivatives substrates for S-adenosyl-L-homocysteine hydrolase?
    Wang M, Zhang J, Andrei D, Kuczera K, Borchardt RT, Wnuk SF.
    J Med Chem; 2005 May 19; 48(10):3649-53. PubMed ID: 15887973
    [Abstract] [Full Text] [Related]

  • 16. Structure-activity relationship of 5'-substituted fluoro-neplanocin a analogues as potent inhibitors of S-adenosylhomocysteine hydrolase.
    Moon HR, Lee KM, Lee JH, Lee SK, Park SB, Chun MW, Jeong LS.
    Nucleosides Nucleotides Nucleic Acids; 2005 May 19; 24(5-7):707-8. PubMed ID: 16248019
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of fluorinated cyclopentenyladenine as potent inhibitor of S-adenosylhomocysteine hydrolase.
    Kim HO, Yoo SJ, Ahn HS, Choi WJ, Moon HR, Lee KM, Chun MW, Jeong LS.
    Bioorg Med Chem Lett; 2004 May 03; 14(9):2091-3. PubMed ID: 15080985
    [Abstract] [Full Text] [Related]

  • 18. Anticancer and antiviral effects and inactivation of S-adenosyl-L-homocysteine hydrolase with 5'-carboxaldehydes and oximes synthesized from adenosine and sugar-modified analogues.
    Wnuk SF, Yuan CS, Borchardt RT, Balzarini J, De Clercq E, Robins MJ.
    J Med Chem; 1997 May 23; 40(11):1608-18. PubMed ID: 9171871
    [Abstract] [Full Text] [Related]

  • 19. Enantiomeric 3-deaza-1',6'-isoneplanocin and its 3-bromo analogue: Synthesis by the Ullmann reaction and their antiviral properties.
    Liu C, Chen Q, Schneller SW.
    Bioorg Med Chem Lett; 2016 Feb 01; 26(3):928-930. PubMed ID: 26750250
    [Abstract] [Full Text] [Related]

  • 20. 6'-Fluoro-3-deazaneplanocin: Synthesis and antiviral properties, including Ebola.
    Liu C, Chen Q, Cardinale S, Bowlin TL, Schneller SW.
    Bioorg Med Chem Lett; 2018 Dec 15; 28(23-24):3674-3675. PubMed ID: 30385162
    [Abstract] [Full Text] [Related]

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