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709 related items for PubMed ID: 16684125

  • 1. Effect of stealthy liposomal topotecan plus amlodipine on the multidrug-resistant leukaemia cells in vitro and xenograft in mice.
    Li X, Lu WL, Liang GW, Ruan GR, Hong HY, Long C, Zhang YT, Liu Y, Wang JC, Zhang X, Zhang Q.
    Eur J Clin Invest; 2006 Jun; 36(6):409-18. PubMed ID: 16684125
    [Abstract] [Full Text] [Related]

  • 2. A novel stealth liposomal topotecan with amlodipine: apoptotic effect is associated with deletion of intracellular Ca2+ by amlodipine thus leading to an enhanced antitumor activity in leukemia.
    Li X, Ruan GR, Lu WL, Hong HY, Liang GW, Zhang YT, Liu Y, Long C, Ma X, Yuan L, Wang JC, Zhang X, Zhang Q.
    J Control Release; 2006 May 15; 112(2):186-98. PubMed ID: 16516327
    [Abstract] [Full Text] [Related]

  • 3. Enhanced therapeutic effects on the multi-drug resistant human leukemia cells in vitro and xenograft in mice using the stealthy liposomal vincristine plus quinacrine.
    Liang GW, Lu WL, Wu JW, Zhao JH, Hong HY, Long C, Li T, Zhang YT, Zhang H, Wang JC, Zhang X, Zhang Q.
    Fundam Clin Pharmacol; 2008 Aug 15; 22(4):429-37. PubMed ID: 18705753
    [Abstract] [Full Text] [Related]

  • 4. Anti-tumour effects of HL-37, a novel anthracene derivative, in-vivo and in-vitro.
    Xie SQ, Hu GQ, Zhang ZQ, Xu M, Ji BS.
    J Pharm Pharmacol; 2008 Feb 15; 60(2):213-9. PubMed ID: 18237469
    [Abstract] [Full Text] [Related]

  • 5. Dual-targeting topotecan liposomes modified with tamoxifen and wheat germ agglutinin significantly improve drug transport across the blood-brain barrier and survival of brain tumor-bearing animals.
    Du J, Lu WL, Ying X, Liu Y, Du P, Tian W, Men Y, Guo J, Zhang Y, Li RJ, Zhou J, Lou JN, Wang JC, Zhang X, Zhang Q.
    Mol Pharm; 2009 Feb 15; 6(3):905-17. PubMed ID: 19344115
    [Abstract] [Full Text] [Related]

  • 6. A potential target associated with both cancer and cancer stem cells: a combination therapy for eradication of breast cancer using vinorelbine stealthy liposomes plus parthenolide stealthy liposomes.
    Liu Y, Lu WL, Guo J, Du J, Li T, Wu JW, Wang GL, Wang JC, Zhang X, Zhang Q.
    J Control Release; 2008 Jul 02; 129(1):18-25. PubMed ID: 18466993
    [Abstract] [Full Text] [Related]

  • 7. Antitumor activity of troxacitabine (Troxatyl) against anthracycline-resistant human xenografts.
    Gourdeau H, Genne P, Kadhim S, Bibeau L, Duchamp O, Ouellet F, deMuys JM, Bouffard DY, Attardo G.
    Cancer Chemother Pharmacol; 2002 Dec 02; 50(6):490-6. PubMed ID: 12451476
    [Abstract] [Full Text] [Related]

  • 8. The role of topotecan for extending the platinum-free interval in recurrent ovarian cancer: an in vitro model.
    Horowitz NS, Hua J, Gibb RK, Mutch DG, Herzog TJ.
    Gynecol Oncol; 2004 Jul 02; 94(1):67-73. PubMed ID: 15262121
    [Abstract] [Full Text] [Related]

  • 9. Reversal of multidrug resistance of cancer through inhibition of P-glycoprotein by 5-bromotetrandrine.
    Jin J, Wang FP, Wei H, Liu G.
    Cancer Chemother Pharmacol; 2005 Feb 02; 55(2):179-88. PubMed ID: 15378274
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and evaluation of (2-(4-methoxyphenyl)-4-quinolinyl)(2-piperidinyl)methanol (NSC23925) isomers to reverse multidrug resistance in cancer.
    Duan Z, Li X, Huang H, Yuan W, Zheng SL, Liu X, Zhang Z, Choy E, Harmon D, Mankin H, Hornicek F.
    J Med Chem; 2012 Apr 12; 55(7):3113-21. PubMed ID: 22400811
    [Abstract] [Full Text] [Related]

  • 11. Determination of the optimal combination chemotherapy regimen for treatment of platinum-resistant ovarian cancer in nude mouse model.
    Saucier JM, Yu J, Gaikwad A, Coleman RL, Wolf JK, Smith JA.
    J Oncol Pharm Pract; 2007 Mar 12; 13(1):39-45. PubMed ID: 17621566
    [Abstract] [Full Text] [Related]

  • 12.
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    [No Abstract] [Full Text] [Related]

  • 13. Mitochondrial targeting topotecan-loaded liposomes for treating drug-resistant breast cancer and inhibiting invasive metastases of melanoma.
    Yu Y, Wang ZH, Zhang L, Yao HJ, Zhang Y, Li RJ, Ju RJ, Wang XX, Zhou J, Li N, Lu WL.
    Biomaterials; 2012 Feb 12; 33(6):1808-20. PubMed ID: 22136714
    [Abstract] [Full Text] [Related]

  • 14. Substituted tetrahydroisoquinoline compound B3 inhibited P-glycoprotein-mediated multidrug resistance in-vitro and in-vivo.
    Fang W, Li Y, Cai Y, Kang K, Yan F, Liu G, Huang W.
    J Pharm Pharmacol; 2007 Dec 12; 59(12):1649-55. PubMed ID: 18053326
    [Abstract] [Full Text] [Related]

  • 15. STI571 combined with vincristine greatly suppressed the tumor formation of multidrug-resistant K562 cells in a human-nude mice xenograft model.
    Gao L, Chen L, Fei XH, Qiu HY, Zhou H, Wang JM.
    Chin Med J (Engl); 2006 Jun 05; 119(11):911-8. PubMed ID: 16780770
    [Abstract] [Full Text] [Related]

  • 16. Effective schedules of exposure of medulloblastoma and rhabdomyosarcoma xenografts to topotecan correlate with in vitro assays.
    Pawlik CA, Houghton PJ, Stewart CF, Cheshire PJ, Richmond LB, Danks MK.
    Clin Cancer Res; 1998 Aug 05; 4(8):1995-2002. PubMed ID: 9717830
    [Abstract] [Full Text] [Related]

  • 17. Sanguinarine overcomes P-glycoprotein-mediated multidrug-resistance via induction of apoptosis and oncosis in CEM-VLB 1000 cells.
    Weerasinghe P, Hallock S, Tang SC, Trump B, Liepins A.
    Exp Toxicol Pathol; 2006 Aug 05; 58(1):21-30. PubMed ID: 16735106
    [Abstract] [Full Text] [Related]

  • 18. Targeting therapy with mitosomal daunorubicin plus amlodipine has the potential to circumvent intrinsic resistant breast cancer.
    Zhang Y, Li RJ, Ying X, Tian W, Yao HJ, Men Y, Yu Y, Zhang L, Ju RJ, Wang XX, Zhou J, Chen JX, Li N, Lu WL.
    Mol Pharm; 2011 Feb 07; 8(1):162-75. PubMed ID: 21062083
    [Abstract] [Full Text] [Related]

  • 19. Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines.
    Vanhoefer U, Müller MR, Hilger RA, Lindtner B, Klaassen U, Schleucher N, Rustum YM, Seeber S, Harstrick A.
    Br J Cancer; 1999 Dec 07; 81(8):1304-10. PubMed ID: 10604726
    [Abstract] [Full Text] [Related]

  • 20. Liposomal encapsulation of topotecan enhances anticancer efficacy in murine and human xenograft models.
    Tardi P, Choice E, Masin D, Redelmeier T, Bally M, Madden TD.
    Cancer Res; 2000 Jul 01; 60(13):3389-93. PubMed ID: 10910044
    [Abstract] [Full Text] [Related]

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