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210 related items for PubMed ID: 16685436

  • 1. RNAi-mediated downregulation of urokinase plasminogen activator and its receptor in human meningioma cells inhibits tumor invasion and growth.
    Kondraganti S, Gondi CS, McCutcheon I, Dinh DH, Gujrati M, Rao JS, Olivero WC.
    Int J Oncol; 2006 Jun; 28(6):1353-60. PubMed ID: 16685436
    [Abstract] [Full Text] [Related]

  • 2. RNA interference-mediated targeting of urokinase plasminogen activator receptor and matrix metalloproteinase-9 gene expression in the IOMM-lee malignant meningioma cell line inhibits tumor growth, tumor cell invasion and angiogenesis.
    Tummalapalli P, Gondi CS, Dinh DH, Gujrati M, Rao JS.
    Int J Oncol; 2007 Jul; 31(1):5-17. PubMed ID: 17549400
    [Abstract] [Full Text] [Related]

  • 3. Radiation-inducible silencing of uPA and uPAR in vitro and in vivo in meningioma.
    Rao Gogineni V, Kumar Nalla A, Gupta R, Gorantla B, Gujrati M, Dinh DH, Rao JS.
    Int J Oncol; 2010 Apr; 36(4):809-16. PubMed ID: 20198323
    [Abstract] [Full Text] [Related]

  • 4. uPA/uPAR downregulation inhibits radiation-induced migration, invasion and angiogenesis in IOMM-Lee meningioma cells and decreases tumor growth in vivo.
    Kargiotis O, Chetty C, Gogineni V, Gondi CS, Pulukuri SM, Kyritsis AP, Gujrati M, Klopfenstein JD, Dinh DH, Rao JS.
    Int J Oncol; 2008 Nov; 33(5):937-47. PubMed ID: 18949356
    [Abstract] [Full Text] [Related]

  • 5. Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo.
    Gupta R, Rao Gogineni V, Nalla AK, Chetty C, Klopfenstein JD, Tsung AJ, Mohanam S, Rao JS.
    Int J Oncol; 2011 Apr; 38(4):973-83. PubMed ID: 21290090
    [Abstract] [Full Text] [Related]

  • 6. Intraperitoneal injection of a hairpin RNA-expressing plasmid targeting urokinase-type plasminogen activator (uPA) receptor and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice.
    Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS.
    Clin Cancer Res; 2007 Jul 15; 13(14):4051-60. PubMed ID: 17634529
    [Abstract] [Full Text] [Related]

  • 7. RNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo.
    Pulukuri SM, Gondi CS, Lakka SS, Jutla A, Estes N, Gujrati M, Rao JS.
    J Biol Chem; 2005 Oct 28; 280(43):36529-40. PubMed ID: 16127174
    [Abstract] [Full Text] [Related]

  • 8. Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas.
    Lakka SS, Gondi CS, Dinh DH, Olivero WC, Gujrati M, Rao VH, Sioka C, Rao JS.
    J Biol Chem; 2005 Jun 10; 280(23):21882-92. PubMed ID: 15824107
    [Abstract] [Full Text] [Related]

  • 9. uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma.
    Gupta R, Nalla AK, Gogineni VR, Chetty C, Bhoopathi P, Klopfenstein JD, Tsung AJ, Mohanam S, Rao JS.
    PLoS One; 2011 Feb 11; 6(2):e17123. PubMed ID: 21347260
    [Abstract] [Full Text] [Related]

  • 10. siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells.
    Subramanian R, Gondi CS, Lakka SS, Jutla A, Rao JS.
    Int J Oncol; 2006 Apr 11; 28(4):831-9. PubMed ID: 16525631
    [Abstract] [Full Text] [Related]

  • 11. uPAR and cathepsin B shRNA impedes TGF-β1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway.
    Gogineni VR, Gupta R, Nalla AK, Velpula KK, Rao JS.
    Cell Death Dis; 2012 Dec 06; 3(12):e439. PubMed ID: 23222509
    [Abstract] [Full Text] [Related]

  • 12. Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor.
    Raghu H, Gondi CS, Dinh DH, Gujrati M, Rao JS.
    Mol Cancer; 2011 Oct 17; 10():130. PubMed ID: 22004682
    [Abstract] [Full Text] [Related]

  • 13. Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis.
    Gondi CS, Lakka SS, Yanamandra N, Siddique K, Dinh DH, Olivero WC, Gujrati M, Rao JS.
    Oncogene; 2003 Sep 04; 22(38):5967-75. PubMed ID: 12955075
    [Abstract] [Full Text] [Related]

  • 14. RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.
    Kunigal S, Lakka SS, Gondi CS, Estes N, Rao JS.
    Int J Cancer; 2007 Nov 15; 121(10):2307-16. PubMed ID: 17657740
    [Abstract] [Full Text] [Related]

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  • 16. Downregulation of uPA, uPAR and MMP-9 using small, interfering, hairpin RNA (siRNA) inhibits glioma cell invasion, angiogenesis and tumor growth.
    Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M, Rao JS.
    Neuron Glia Biol; 2004 May 15; 1(2):165-76. PubMed ID: 16804563
    [Abstract] [Full Text] [Related]

  • 17. Targeting of urokinase plasminogen activator receptor in human pancreatic carcinoma cells inhibits c-Met- and insulin-like growth factor-I receptor-mediated migration and invasion and orthotopic tumor growth in mice.
    Bauer TW, Liu W, Fan F, Camp ER, Yang A, Somcio RJ, Bucana CD, Callahan J, Parry GC, Evans DB, Boyd DD, Mazar AP, Ellis LM.
    Cancer Res; 2005 Sep 01; 65(17):7775-81. PubMed ID: 16140945
    [Abstract] [Full Text] [Related]

  • 18. Suppression of uPA and uPAR blocks radiation-induced MCP-1 mediated recruitment of endothelial cells in meningioma.
    Nalla AK, Gogineni VR, Gupta R, Dinh DH, Rao JS.
    Cell Signal; 2011 Aug 01; 23(8):1299-310. PubMed ID: 21426933
    [Abstract] [Full Text] [Related]

  • 19. Amino-terminal fragment of urokinase inhibits tumor cell invasion in vitro and in vivo: respective contribution of the urokinase plasminogen activator receptor-dependent or -independent pathway.
    Li H, Soria C, Griscelli F, Opolon P, Soria J, Yeh P, Legrand C, Vannier JP, Belin D, Perricaudet M, Lu H.
    Hum Gene Ther; 2005 Oct 01; 16(10):1157-67. PubMed ID: 16218777
    [Abstract] [Full Text] [Related]

  • 20. Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth.
    Lakka SS, Gondi CS, Yanamandra N, Dinh DH, Olivero WC, Gujrati M, Rao JS.
    Cancer Res; 2003 May 15; 63(10):2454-61. PubMed ID: 12750266
    [Abstract] [Full Text] [Related]


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