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Journal Abstract Search

428 related items for PubMed ID: 16724925

  • 1. Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds.
    Reschly EJ, Krasowski MD.
    Curr Drug Metab; 2006 May; 7(4):349-65. PubMed ID: 16724925
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  • 2. Functional evolution of the vitamin D and pregnane X receptors.
    Reschly EJ, Bainy AC, Mattos JJ, Hagey LR, Bahary N, Mada SR, Ou J, Venkataramanan R, Krasowski MD.
    BMC Evol Biol; 2007 Nov 12; 7():222. PubMed ID: 17997857
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  • 7. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
    Moore LB, Parks DJ, Jones SA, Bledsoe RK, Consler TG, Stimmel JB, Goodwin B, Liddle C, Blanchard SG, Willson TM, Collins JL, Kliewer SA.
    J Biol Chem; 2000 May 19; 275(20):15122-7. PubMed ID: 10748001
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  • 9. Ligand recognition by drug-activated nuclear receptors PXR and CAR: structural, site-directed mutagenesis and molecular modeling studies.
    Poso A, Honkakoski P.
    Mini Rev Med Chem; 2006 Aug 19; 6(8):937-47. PubMed ID: 16918499
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  • 10. Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.
    Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT.
    Mol Endocrinol; 2002 May 19; 16(5):977-86. PubMed ID: 11981033
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  • 11. Nuclear receptors PXR and CAR: implications for drug metabolism regulation, pharmacogenomics and beyond.
    Chai X, Zeng S, Xie W.
    Expert Opin Drug Metab Toxicol; 2013 Mar 19; 9(3):253-66. PubMed ID: 23327618
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  • 13. The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.
    Zhang J, Huang W, Qatanani M, Evans RM, Moore DD.
    J Biol Chem; 2004 Nov 19; 279(47):49517-22. PubMed ID: 15358766
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  • 14. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor.
    Kast HR, Goodwin B, Tarr PT, Jones SA, Anisfeld AM, Stoltz CM, Tontonoz P, Kliewer S, Willson TM, Edwards PA.
    J Biol Chem; 2002 Jan 25; 277(4):2908-15. PubMed ID: 11706036
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  • 15. Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands.
    Toell A, Kröncke KD, Kleinert H, Carlberg C.
    J Cell Biochem; 2002 Jan 25; 85(1):72-82. PubMed ID: 11891851
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  • 16. Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR).
    Anderson LE, Dring AM, Hamel LD, Stoner MA.
    Toxicol Lett; 2011 Apr 25; 202(2):148-54. PubMed ID: 21315811
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  • 17. Xenobiotic-sensing nuclear receptors CAR and PXR as drug targets in cholestatic liver disease.
    Kakizaki S, Takizawa D, Tojima H, Yamazaki Y, Mori M.
    Curr Drug Targets; 2009 Nov 25; 10(11):1156-1163. PubMed ID: 19925451
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  • 18. Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR.
    Tolson AH, Wang H.
    Adv Drug Deliv Rev; 2010 Oct 30; 62(13):1238-49. PubMed ID: 20727377
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  • 20. Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio).
    Bainy AC, Kubota A, Goldstone JV, Lille-Langøy R, Karchner SI, Celander MC, Hahn ME, Goksøyr A, Stegeman JJ.
    Aquat Toxicol; 2013 Oct 15; 142-143():447-57. PubMed ID: 24121122
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