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Journal Abstract Search

133 related items for PubMed ID: 16730688

  • 1. Response of human mammary epithelial cells to DNA damage induced by 4-hydroxyequilenin: Lack of p53-mediated G1 arrest.
    Cuendet M, Bolton JL.
    Chem Biol Interact; 2006 Jul 10; 161(3):271-8. PubMed ID: 16730688
    [Abstract] [Full Text] [Related]

  • 2. Equine estrogen metabolite 4-hydroxyequilenin induces anchorage-independent growth of human mammary epithelial MCF-10A cells: differential gene expression.
    Cuendet M, Liu X, Pisha E, Li Y, Yao J, Yu L, Bolton JL.
    Mutat Res; 2004 Jun 04; 550(1-2):109-21. PubMed ID: 15135645
    [Abstract] [Full Text] [Related]

  • 3. A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines.
    Chen Y, Liu X, Pisha E, Constantinou AI, Hua Y, Shen L, van Breemen RB, Elguindi EC, Blond SY, Zhang F, Bolton JL.
    Chem Res Toxicol; 2000 May 04; 13(5):342-50. PubMed ID: 10813650
    [Abstract] [Full Text] [Related]

  • 4. Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models.
    Wang J, Huang S, Xing L, Cui J, Tian Z, Shen H, Jiang X, Yan X, Wang J, Zhang X.
    Arch Toxicol; 2015 Nov 04; 89(11):2015-25. PubMed ID: 25294323
    [Abstract] [Full Text] [Related]

  • 5. Altered apoptotic response in MCF 10A cells treated with the equine estrogen metabolite, 4-hydroxyequilenin.
    Li Y, Yao J, Chang M, Cuendet M, Bolton JL.
    Toxicol Lett; 2004 Dec 30; 154(3):225-33. PubMed ID: 15501614
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of glutathione S-transferase activity by the quinoid metabolites of equine estrogens.
    Chang M, Zhang F, Shen L, Pauss N, Alam I, van Breemen RB, Blond SY, Bolton JL.
    Chem Res Toxicol; 1998 Jul 30; 11(7):758-65. PubMed ID: 9671538
    [Abstract] [Full Text] [Related]

  • 7. Evidence that a metabolite of equine estrogens, 4-hydroxyequilenin, induces cellular transformation in vitro.
    Pisha E, Lui X, Constantinou AI, Bolton JL.
    Chem Res Toxicol; 2001 Jan 30; 14(1):82-90. PubMed ID: 11170511
    [Abstract] [Full Text] [Related]

  • 8. The equine estrogen metabolite 4-hydroxyequilenin causes DNA single-strand breaks and oxidation of DNA bases in vitro.
    Chen Y, Shen L, Zhang F, Lau SS, van Breemen RB, Nikolic D, Bolton JL.
    Chem Res Toxicol; 1998 Sep 30; 11(9):1105-11. PubMed ID: 9760286
    [Abstract] [Full Text] [Related]

  • 9. Catechol estrogen 4-hydroxyequilenin is a substrate and an inhibitor of catechol-O-methyltransferase.
    Yao J, Li Y, Chang M, Wu H, Yang X, Goodman JE, Liu X, Liu H, Mesecar AD, Van Breemen RB, Yager JD, Bolton JL.
    Chem Res Toxicol; 2003 May 30; 16(5):668-75. PubMed ID: 12755597
    [Abstract] [Full Text] [Related]

  • 10. Alkylation of 2'-deoxynucleosides and DNA by the Premarin metabolite 4-hydroxyequilenin semiquinone radical.
    Shen L, Qiu S, Chen Y, Zhang F, van Breemen RB, Nikolic D, Bolton JL.
    Chem Res Toxicol; 1998 Feb 30; 11(2):94-101. PubMed ID: 9511900
    [Abstract] [Full Text] [Related]

  • 11. The major metabolite of equilin, 4-hydroxyequilin, autoxidizes to an o-quinone which isomerizes to the potent cytotoxin 4-hydroxyequilenin-o-quinone.
    Zhang F, Chen Y, Pisha E, Shen L, Xiong Y, van Breemen RB, Bolton JL.
    Chem Res Toxicol; 1999 Feb 30; 12(2):204-13. PubMed ID: 10027800
    [Abstract] [Full Text] [Related]

  • 12. Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha.
    Liu X, Yao J, Pisha E, Yang Y, Hua Y, van Breemen RB, Bolton JL.
    Chem Res Toxicol; 2002 Apr 30; 15(4):512-9. PubMed ID: 11952337
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of cellular enzymes by equine catechol estrogens in human breast cancer cells: specificity for glutathione S-transferase P1-1.
    Yao J, Chang M, Li Y, Pisha E, Liu X, Yao D, Elguindi EC, Blond SY, Bolton JL.
    Chem Res Toxicol; 2002 Jul 30; 15(7):935-42. PubMed ID: 12119004
    [Abstract] [Full Text] [Related]

  • 14. Estrogen Receptor {alpha} Enhances the Rate of Oxidative DNA Damage by Targeting an Equine Estrogen Catechol Metabolite to the Nucleus.
    Wang Z, Wijewickrama GT, Peng KW, Dietz BM, Yuan L, van Breemen RB, Bolton JL, Thatcher GR.
    J Biol Chem; 2009 Mar 27; 284(13):8633-42. PubMed ID: 19158089
    [Abstract] [Full Text] [Related]

  • 15. Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens.
    Wang Z, Chandrasena ER, Yuan Y, Peng KW, van Breemen RB, Thatcher GR, Bolton JL.
    Chem Res Toxicol; 2010 Aug 16; 23(8):1365-73. PubMed ID: 20509668
    [Abstract] [Full Text] [Related]

  • 16. Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity.
    Shen L, Pisha E, Huang Z, Pezzuto JM, Krol E, Alam Z, van Breemen RB, Bolton JL.
    Carcinogenesis; 1997 May 16; 18(5):1093-101. PubMed ID: 9163701
    [Abstract] [Full Text] [Related]

  • 17. Effect of halogenated substituents on the metabolism and estrogenic effects of the equine estrogen, equilenin.
    Liu X, Zhang F, Liu H, Burdette JE, Li Y, Overk CR, Pisha E, Yao J, van Breemen RB, Swanson SM, Bolton JL.
    Chem Res Toxicol; 2003 Jun 16; 16(6):741-9. PubMed ID: 12807357
    [Abstract] [Full Text] [Related]

  • 18. Unexpected hormonal activity of a catechol equine estrogen metabolite reveals reversible glutathione conjugation.
    Peng KW, Chang M, Wang YT, Wang Z, Qin Z, Bolton JL, Thatcher GR.
    Chem Res Toxicol; 2010 Aug 16; 23(8):1374-83. PubMed ID: 20540524
    [Abstract] [Full Text] [Related]

  • 19. F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation.
    Malashicheva AB, Kislyakova TV, Aksenov ND, Osipov KA, Pospelov VA.
    Oncogene; 2000 Aug 10; 19(34):3858-65. PubMed ID: 10951579
    [Abstract] [Full Text] [Related]

  • 20. Resveratrol mediated cell death in cigarette smoke transformed breast epithelial cells is through induction of p21Waf1/Cip1 and inhibition of long patch base excision repair pathway.
    Mohapatra P, Satapathy SR, Das D, Siddharth S, Choudhuri T, Kundu CN.
    Toxicol Appl Pharmacol; 2014 Mar 15; 275(3):221-31. PubMed ID: 24467951
    [Abstract] [Full Text] [Related]

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