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165 related items for PubMed ID: 16734734

  • 1. Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines.
    Kajiguchi T, Yamamoto K, Iida S, Ueda R, Emi N, Naoe T.
    Cancer Sci; 2006 Jun; 97(6):540-5. PubMed ID: 16734734
    [Abstract] [Full Text] [Related]

  • 2. Induction of B-chronic lymphocytic leukemia cell apoptosis by arsenic trioxide involves suppression of the phosphoinositide 3-kinase/Akt survival pathway via c-jun-NH2 terminal kinase activation and PTEN upregulation.
    Redondo-Muñoz J, Escobar-Díaz E, Hernández Del Cerro M, Pandiella A, Terol MJ, García-Marco JA, García-Pardo A.
    Clin Cancer Res; 2010 Sep 01; 16(17):4382-91. PubMed ID: 20534739
    [Abstract] [Full Text] [Related]

  • 3. Arsenic trioxide induces apoptosis in human platelets via C-Jun NH2-terminal kinase activation.
    Wu Y, Dai J, Zhang W, Yan R, Zhang Y, Ruan C, Dai K.
    PLoS One; 2014 Sep 01; 9(1):e86445. PubMed ID: 24466103
    [Abstract] [Full Text] [Related]

  • 4. A combination of sulindac and arsenic trioxide synergistically induces apoptosis in human lung cancer H1299 cells via c-Jun NH2-terminal kinase-dependent Bcl-xL phosphorylation.
    Jin HO, Seo SK, Woo SH, Lee HC, Kim ES, Yoo DH, Lee SJ, An S, Choe TB, Kim JI, Hong SI, Rhee CH, Park IC.
    Lung Cancer; 2008 Sep 01; 61(3):317-27. PubMed ID: 18281123
    [Abstract] [Full Text] [Related]

  • 5. Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.
    Sánchez Y, Simón GP, Calviño E, de Blas E, Aller P.
    J Pharmacol Exp Ther; 2010 Oct 01; 335(1):114-23. PubMed ID: 20605902
    [Abstract] [Full Text] [Related]

  • 6. Ethacrynic acid and a derivative enhance apoptosis in arsenic trioxide-treated myeloid leukemia and lymphoma cells: the role of glutathione S-transferase p1-1.
    Wang R, Liu C, Xia L, Zhao G, Gabrilove J, Waxman S, Jing Y.
    Clin Cancer Res; 2012 Dec 15; 18(24):6690-701. PubMed ID: 23082001
    [Abstract] [Full Text] [Related]

  • 7. Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells.
    Wang R, Xia L, Gabrilove J, Waxman S, Jing Y.
    Leukemia; 2013 Feb 15; 27(2):315-24. PubMed ID: 22751450
    [Abstract] [Full Text] [Related]

  • 8. Novel human neutrophil agonistic properties of arsenic trioxide: involvement of p38 mitogen-activated protein kinase and/or c-jun NH2-terminal MAPK but not extracellular signal-regulated kinases-1/2.
    Binet F, Girard D.
    J Leukoc Biol; 2008 Dec 15; 84(6):1613-22. PubMed ID: 18728151
    [Abstract] [Full Text] [Related]

  • 9. P38 MAPK inhibition enhancing ATO-induced cytotoxicity against multiple myeloma cells.
    Wen J, Cheng HY, Feng Y, Rice L, Liu S, Mo A, Huang J, Zu Y, Ballon DJ, Chang CC.
    Br J Haematol; 2008 Jan 15; 140(2):169-80. PubMed ID: 18173754
    [Abstract] [Full Text] [Related]

  • 10. TG-interacting factor transcriptionally induced by AKT/FOXO3A is a negative regulator that antagonizes arsenic trioxide-induced cancer cell apoptosis.
    Liu ZM, Tseng HY, Cheng YL, Yeh BW, Wu WJ, Huang HS.
    Toxicol Appl Pharmacol; 2015 May 15; 285(1):41-50. PubMed ID: 25791921
    [Abstract] [Full Text] [Related]

  • 11. Epoxyeicosatrienoic acids attenuate reactive oxygen species level, mitochondrial dysfunction, caspase activation, and apoptosis in carcinoma cells treated with arsenic trioxide.
    Liu L, Chen C, Gong W, Li Y, Edin ML, Zeldin DC, Wang DW.
    J Pharmacol Exp Ther; 2011 Nov 15; 339(2):451-63. PubMed ID: 21846841
    [Abstract] [Full Text] [Related]

  • 12. JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells.
    Davison K, Mann KK, Waxman S, Miller WH.
    Blood; 2004 May 01; 103(9):3496-502. PubMed ID: 14701702
    [Abstract] [Full Text] [Related]

  • 13. Sustained activation of c-jun-terminal kinase (JNK) is closely related to arsenic trioxide-induced apoptosis in an acute myeloid leukemia (M2)-derived cell line, NKM-1.
    Kajiguchi T, Yamamoto K, Hossain K, Akhand AA, Nakashima I, Naoe T, Saito H, Emi N.
    Leukemia; 2003 Nov 01; 17(11):2189-95. PubMed ID: 12931215
    [Abstract] [Full Text] [Related]

  • 14. Arsenic trioxide and proteasome inhibitor bortezomib synergistically induce apoptosis in leukemic cells: the role of protein kinase Cdelta.
    Yan H, Wang YC, Li D, Wang Y, Liu W, Wu YL, Chen GQ.
    Leukemia; 2007 Jul 01; 21(7):1488-95. PubMed ID: 17495969
    [Abstract] [Full Text] [Related]

  • 15. Arsenic trioxide-mediated growth inhibition of myeloma cells is associated with an extrinsic or intrinsic signaling pathway through activation of TRAIL or TRAIL receptor 2.
    Wu X, Shi J, Wu Y, Tao Y, Hou J, Meng X, Hu X, Han Y, Jiang W, Tang S, Zangari M, Tricot G, Zhan F.
    Cancer Biol Ther; 2010 Dec 01; 10(11):1201-14. PubMed ID: 20953137
    [Abstract] [Full Text] [Related]

  • 16. Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
    Ramos AM, Fernandez C, Amrán D, Esteban D, de Blas E, Palacios MA, Aller P.
    J Cell Physiol; 2006 Dec 01; 209(3):1006-15. PubMed ID: 16972261
    [Abstract] [Full Text] [Related]

  • 17. Realgar nanoparticles versus ATO arsenic compounds induce in vitro and in vivo activity against multiple myeloma.
    Cholujova D, Bujnakova Z, Dutkova E, Hideshima T, Groen RW, Mitsiades CS, Richardson PG, Dorfman DM, Balaz P, Anderson KC, Jakubikova J.
    Br J Haematol; 2017 Dec 01; 179(5):756-771. PubMed ID: 29048129
    [Abstract] [Full Text] [Related]

  • 18. Arsenic trioxide-induced apoptosis in myeloma cells: p53-dependent G1 or G2/M cell cycle arrest, activation of caspase-8 or caspase-9, and synergy with APO2/TRAIL.
    Liu Q, Hilsenbeck S, Gazitt Y.
    Blood; 2003 May 15; 101(10):4078-87. PubMed ID: 12531793
    [Abstract] [Full Text] [Related]

  • 19. Reactive oxygen species are not required for an arsenic trioxide-induced antioxidant response or apoptosis.
    Morales AA, Gutman D, Cejas PJ, Lee KP, Boise LH.
    J Biol Chem; 2009 May 08; 284(19):12886-95. PubMed ID: 19279006
    [Abstract] [Full Text] [Related]

  • 20. Proteomic and functional analyses reveal a dual molecular mechanism underlying arsenic-induced apoptosis in human multiple myeloma cells.
    Ge F, Lu XP, Zeng HL, He QY, Xiong S, Jin L, He QY.
    J Proteome Res; 2009 Jun 08; 8(6):3006-19. PubMed ID: 19364129
    [Abstract] [Full Text] [Related]

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