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Journal Abstract Search

331 related items for PubMed ID: 16740692

  • 1. Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.
    Toretsky JA, Erkizan V, Levenson A, Abaan OD, Parvin JD, Cripe TP, Rice AM, Lee SB, Uren A.
    Cancer Res; 2006 Jun 01; 66(11):5574-81. PubMed ID: 16740692
    [Abstract] [Full Text] [Related]

  • 2. RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1.
    Erkizan HV, Schneider JA, Sajwan K, Graham GT, Griffin B, Chasovskikh S, Youbi SE, Kallarakal A, Chruszcz M, Padmanabhan R, Casey JL, Üren A, Toretsky JA.
    Nucleic Acids Res; 2015 Jan 01; 43(2):1069-80. PubMed ID: 25564528
    [Abstract] [Full Text] [Related]

  • 3. Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells.
    Tirado OM, Mateo-Lozano S, Villar J, Dettin LE, Llort A, Gallego S, Ban J, Kovar H, Notario V.
    Cancer Res; 2006 Oct 15; 66(20):9937-47. PubMed ID: 17047056
    [Abstract] [Full Text] [Related]

  • 4. A polypeptide from the junction region sequence of EWS-FLI1 inhibits Ewing's sarcoma cells, interacts with the EWS-FLI1 and partner proteins.
    Thangaretnam KP, Gopisetty G, Ramanathan P, Rajkumar T.
    Sci Rep; 2017 Aug 03; 7(1):7172. PubMed ID: 28775288
    [Abstract] [Full Text] [Related]

  • 5. Single-chain antibodies to the EWS NH(2) terminus structurally discriminate between intact and chimeric EWS in Ewing's sarcoma and interfere with the transcriptional activity of EWS in vivo.
    Aryee DN, Kreppel M, Bachmaier R, Uren A, Muehlbacher K, Wagner S, Breiteneder H, Ban J, Toretsky JA, Kovar H.
    Cancer Res; 2006 Oct 15; 66(20):9862-9. PubMed ID: 17047047
    [Abstract] [Full Text] [Related]

  • 6. Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.
    Selvanathan SP, Graham GT, Erkizan HV, Dirksen U, Natarajan TG, Dakic A, Yu S, Liu X, Paulsen MT, Ljungman ME, Wu CH, Lawlor ER, Üren A, Toretsky JA.
    Proc Natl Acad Sci U S A; 2015 Mar 17; 112(11):E1307-16. PubMed ID: 25737553
    [Abstract] [Full Text] [Related]

  • 7. Ewing's sarcoma oncoprotein EWS-FLI1: the perfect target without a therapeutic agent.
    Uren A, Toretsky JA.
    Future Oncol; 2005 Aug 17; 1(4):521-8. PubMed ID: 16556028
    [Abstract] [Full Text] [Related]

  • 8. A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis.
    Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF.
    Dis Model Mech; 2012 Jan 17; 5(1):95-106. PubMed ID: 21979944
    [Abstract] [Full Text] [Related]

  • 9. Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing's sarcoma in vitro.
    Jully B, Vijayalakshmi R, Gopal G, Sabitha K, Rajkumar T.
    BMC Cancer; 2012 Nov 12; 12():513. PubMed ID: 23145994
    [Abstract] [Full Text] [Related]

  • 10. PI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.
    Giorgi C, Boro A, Rechfeld F, Lopez-Garcia LA, Gierisch ME, Schäfer BW, Niggli FK.
    Oncotarget; 2015 Oct 06; 6(30):28895-910. PubMed ID: 26336820
    [Abstract] [Full Text] [Related]

  • 11. Impairment of p53 acetylation by EWS-Fli1 chimeric protein in Ewing family tumors.
    Li Y, Li X, Fan G, Fukushi J, Matsumoto Y, Iwamoto Y, Zhu Y.
    Cancer Lett; 2012 Jul 01; 320(1):14-22. PubMed ID: 22266186
    [Abstract] [Full Text] [Related]

  • 12. Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma.
    Boro A, Prêtre K, Rechfeld F, Thalhammer V, Oesch S, Wachtel M, Schäfer BW, Niggli FK.
    Int J Cancer; 2012 Nov 01; 131(9):2153-64. PubMed ID: 22323082
    [Abstract] [Full Text] [Related]

  • 13. Identification of an inhibitor of the EWS-FLI1 oncogenic transcription factor by high-throughput screening.
    Grohar PJ, Woldemichael GM, Griffin LB, Mendoza A, Chen QR, Yeung C, Currier DG, Davis S, Khanna C, Khan J, McMahon JB, Helman LJ.
    J Natl Cancer Inst; 2011 Jun 22; 103(12):962-78. PubMed ID: 21653923
    [Abstract] [Full Text] [Related]

  • 14. A molecular function map of Ewing's sarcoma.
    Kauer M, Ban J, Kofler R, Walker B, Davis S, Meltzer P, Kovar H.
    PLoS One; 2009 Jun 22; 4(4):e5415. PubMed ID: 19404404
    [Abstract] [Full Text] [Related]

  • 15. Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma.
    Niedan S, Kauer M, Aryee DN, Kofler R, Schwentner R, Meier A, Pötschger U, Kontny U, Kovar H.
    Oncogene; 2014 Jul 24; 33(30):3927-38. PubMed ID: 23995784
    [Abstract] [Full Text] [Related]

  • 16. The Promoter-Associated Noncoding RNA pncCCND1_B Assembles a Protein-RNA Complex to Regulate Cyclin D1 Transcription in Ewing Sarcoma.
    Palombo R, Frisone P, Fidaleo M, Mercatelli N, Sette C, Paronetto MP.
    Cancer Res; 2019 Jul 15; 79(14):3570-3582. PubMed ID: 31072811
    [Abstract] [Full Text] [Related]

  • 17. A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma.
    Erkizan HV, Kong Y, Merchant M, Schlottmann S, Barber-Rotenberg JS, Yuan L, Abaan OD, Chou TH, Dakshanamurthy S, Brown ML, Uren A, Toretsky JA.
    Nat Med; 2009 Jul 15; 15(7):750-6. PubMed ID: 19584866
    [Abstract] [Full Text] [Related]

  • 18. FOXO1 is a direct target of EWS-Fli1 oncogenic fusion protein in Ewing's sarcoma cells.
    Yang L, Hu HM, Zielinska-Kwiatkowska A, Chansky HA.
    Biochem Biophys Res Commun; 2010 Nov 05; 402(1):129-34. PubMed ID: 20933505
    [Abstract] [Full Text] [Related]

  • 19. PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis.
    Abaan OD, Levenson A, Khan O, Furth PA, Uren A, Toretsky JA.
    Oncogene; 2005 Apr 14; 24(16):2715-22. PubMed ID: 15782144
    [Abstract] [Full Text] [Related]

  • 20. GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.
    Beauchamp E, Bulut G, Abaan O, Chen K, Merchant A, Matsui W, Endo Y, Rubin JS, Toretsky J, Uren A.
    J Biol Chem; 2009 Apr 03; 284(14):9074-82. PubMed ID: 19189974
    [Abstract] [Full Text] [Related]

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