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113 related items for PubMed ID: 1674942

  • 1. Replacement of P1 Leu18 by Glu18 in the reactive site of turkey ovomucoid third domain converts it into a strong inhibitor of Glu-specific Streptomyces griseus proteinase (GluSGP).
    Komiyama T, Bigler TL, Yoshida N, Noda K, Laskowski M.
    J Biol Chem; 1991 Jun 15; 266(17):10727-30. PubMed ID: 1674942
    [Abstract] [Full Text] [Related]

  • 2. Turkey ovomucoid third domain inhibits eight different serine proteinases of varied specificity on the same ...Leu18-Glu19 ... reactive site.
    Ardelt W, Laskowski M.
    Biochemistry; 1985 Sep 24; 24(20):5313-20. PubMed ID: 3907700
    [Abstract] [Full Text] [Related]

  • 3. Arg15-Lys17-Arg18 turkey ovomucoid third domain inhibits human furin.
    Lu W, Zhang W, Molloy SS, Thomas G, Ryan K, Chiang Y, Anderson S, Laskowski M.
    J Biol Chem; 1993 Jul 15; 268(20):14583-5. PubMed ID: 8325837
    [Abstract] [Full Text] [Related]

  • 4. Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I.
    Bateman KS, Huang K, Anderson S, Lu W, Qasim MA, Laskowski M, James MN.
    J Mol Biol; 2001 Jan 26; 305(4):839-49. PubMed ID: 11162096
    [Abstract] [Full Text] [Related]

  • 5. Water molecules participate in proteinase-inhibitor interactions: crystal structures of Leu18, Ala18, and Gly18 variants of turkey ovomucoid inhibitor third domain complexed with Streptomyces griseus proteinase B.
    Huang K, Lu W, Anderson S, Laskowski M, James MN.
    Protein Sci; 1995 Oct 26; 4(10):1985-97. PubMed ID: 8535235
    [Abstract] [Full Text] [Related]

  • 6. Binding of amino acid side chains to preformed cavities: interaction of serine proteinases with turkey ovomucoid third domains with coded and noncoded P1 residues.
    Bigler TL, Lu W, Park SJ, Tashiro M, Wieczorek M, Wynn R, Laskowski M.
    Protein Sci; 1993 May 26; 2(5):786-99. PubMed ID: 8495199
    [Abstract] [Full Text] [Related]

  • 7. Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases.
    Qasim MA, Lu SM, Ding J, Bateman KS, James MN, Anderson S, Song J, Markley JL, Ganz PJ, Saunders CW, Laskowski M.
    Biochemistry; 1999 Jun 01; 38(22):7142-50. PubMed ID: 10353824
    [Abstract] [Full Text] [Related]

  • 8. Ionizable P1 residues in serine proteinase inhibitors undergo large pK shifts on complex formation.
    Abul Qasim M, Ranjbar MR, Wynn R, Anderson S, Laskowski M.
    J Biol Chem; 1995 Nov 17; 270(46):27419-22. PubMed ID: 7499197
    [Abstract] [Full Text] [Related]

  • 9. Binding of amino acid side-chains to S1 cavities of serine proteinases.
    Lu W, Apostol I, Qasim MA, Warne N, Wynn R, Zhang WL, Anderson S, Chiang YW, Ogin E, Rothberg I, Ryan K, Laskowski M.
    J Mol Biol; 1997 Feb 21; 266(2):441-61. PubMed ID: 9047374
    [Abstract] [Full Text] [Related]

  • 10. Interscaffolding additivity. Association of P1 variants of eglin c and of turkey ovomucoid third domain with serine proteinases.
    Qasim MA, Ganz PJ, Saunders CW, Bateman KS, James MN, Laskowski M.
    Biochemistry; 1997 Feb 18; 36(7):1598-607. PubMed ID: 9048543
    [Abstract] [Full Text] [Related]

  • 11. Additivity-based design of the strongest possible turkey ovomucoid third domain inhibitors for porcine pancreatic elastase (PPE) and Streptomyces griseus protease B (SGPB).
    Qasim MA, Wang L, Qasim S, Lu S, Lu W, Wynn R, Yi ZP, Laskowski M.
    FEBS Lett; 2013 Sep 17; 587(18):3021-6. PubMed ID: 23892073
    [Abstract] [Full Text] [Related]

  • 12. Probing intermolecular main chain hydrogen bonding in serine proteinase-protein inhibitor complexes: chemical synthesis of backbone-engineered turkey ovomucoid third domain.
    Lu W, Qasim MA, Laskowski M, Kent SB.
    Biochemistry; 1997 Jan 28; 36(4):673-9. PubMed ID: 9020764
    [Abstract] [Full Text] [Related]

  • 13. Subsite mapping of an acidic amino acid-specific endopeptidase from Streptomyces griseus, GluSGP, and protease V8.
    Nagata K, Yoshida N, Ogata F, Araki M, Noda K.
    J Biochem; 1991 Dec 28; 110(6):859-62. PubMed ID: 1794975
    [Abstract] [Full Text] [Related]

  • 14. Refined crystal structure of the molecular complex of Streptomyces griseus protease B, a serine protease, with the third domain of the ovomucoid inhibitor from turkey.
    Fujinaga M, Read RJ, Sielecki A, Ardelt W, Laskowski M, James MN.
    Proc Natl Acad Sci U S A; 1982 Aug 28; 79(16):4868-72. PubMed ID: 6750612
    [Abstract] [Full Text] [Related]

  • 15. Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution.
    Read RJ, Fujinaga M, Sielecki AR, James MN.
    Biochemistry; 1983 Sep 13; 22(19):4420-33. PubMed ID: 6414511
    [Abstract] [Full Text] [Related]

  • 16. Structural and functional study of an Anemonia elastase inhibitor, a "nonclassical" Kazal-type inhibitor from Anemonia sulcata.
    Hemmi H, Kumazaki T, Yoshizawa-Kumagaye K, Nishiuchi Y, Yoshida T, Ohkubo T, Kobayashi Y.
    Biochemistry; 2005 Jul 19; 44(28):9626-36. PubMed ID: 16008348
    [Abstract] [Full Text] [Related]

  • 17. Crystal and molecular structures of the complex of alpha-chymotrypsin with its inhibitor turkey ovomucoid third domain at 1.8 A resolution.
    Fujinaga M, Sielecki AR, Read RJ, Ardelt W, Laskowski M, James MN.
    J Mol Biol; 1987 May 20; 195(2):397-418. PubMed ID: 3477645
    [Abstract] [Full Text] [Related]

  • 18. Purification and amino acid sequence of a bitter gourd inhibitor against an acidic amino acid-specific endopeptidase of Streptomyces griseus.
    Ogata F, Miyata T, Fujii N, Yoshida N, Noda K, Makisumi S, Ito A.
    J Biol Chem; 1991 Sep 05; 266(25):16715-21. PubMed ID: 1679433
    [Abstract] [Full Text] [Related]

  • 19. NMR determination of pKa values for Asp, Glu, His, and Lys mutants at each variable contiguous enzyme-inhibitor contact position of the turkey ovomucoid third domain.
    Song J, Laskowski M, Qasim MA, Markley JL.
    Biochemistry; 2003 Mar 18; 42(10):2847-56. PubMed ID: 12627950
    [Abstract] [Full Text] [Related]

  • 20. NMR chemical shift mapping of the binding site of a protein proteinase inhibitor: changes in the (1)H, (13)C and (15)N NMR chemical shifts of turkey ovomucoid third domain upon binding to bovine chymotrypsin A(alpha).
    Song J, Markley JL.
    J Mol Recognit; 2001 Mar 18; 14(3):166-71. PubMed ID: 11391787
    [Abstract] [Full Text] [Related]

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